Two postdoctoral positions are open in the laboratory of Dr. Mihaela Serpe, NICHD, NIH. We study mechanisms of synapse assembly and homeostasis using Drosophila neuromuscular junction as model for glutamatergic synapse development. We previously found that fly receptors require an essential auxiliary protein, Neto, for their synaptic recruitment and function. We are currently examining how Neto-mediated interactions control synapse assembly and plasticity. We are also investigating how signaling by BMPs coordinates synapse growth and activity. We address the mechanisms underlying these processes using multidisciplinary approaches, including genetics, molecular and cellular biology, single cell RNA-seq and electrophysiology recordings in live animals and reconstituted systems.
Applicants must have a Ph.D. and/or M.D. degree with less than five years of postdoctoral experience. A strong background in cell biology, biochemistry or electrophysiology is required. Electrophysiologists interested in receptor gating mechanisms are particularly encouraged to apply. Salary is competitive, commensurate with experience.
Inquiries regarding these positions should be directed to Dr. Serpe (firstname.lastname@example.org). To apply, please submit statement of research interests, CV and the names of three or more references.
The NIH is dedicated to building a diverse community in its training and employment programs.