Proneural bHLH transcription factors are master regulators of neural cell fate determination and differentiation and important components of neuronal reprogramming strategies in mammals. It is not well understood how the activities and functions of proneural bHLH proteins are controlled post-transcriptionally. We will use Drosophila eye development to identify and characterize novel regulators of proneural bHLH proteins, in a multidisciplinary approach that may involve developmental genetic studies, protein biochemistry, and genetic screens coupled to modern whole-genome sequencing approaches.
Send CV, research interests, and reference contact information: Dr. Nicholas Baker (firstname.lastname@example.org)
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