Three NIH Funding Opportunities to support the Cellular Senescence Network (SenNet) program

Posted 1/13/2021

The NIH Common Fund has issued three funding opportunity announcements (FOAs) to support the new Cellular Senescence Network (SenNet) program. The program aims to catalyze the development of a framework for mapping cellular senescence and its associated secretory phenotype at high resolution, and to provide atlases of cellular senescence in multiple tissues across various states of human health, and across the lifespan. In addition, it is expected that the SenNet will provide comprehensive sets of biomarkers describing heterogenous senescent cell states.  Applications for each FOA are due March 8, 2021. Additional details about the program will be posted on the SenNet webpage as they become available.

In these FOAs, NIH is calling for applications in the following areas:

Tissue Mapping Centers (U54 - Clinical Trial Not Allowed): RFA RM-21-008

  • This opportunity is to support the generation of extensive data from high-content, high-throughput imaging, omics, and other technologies as appropriate, to build, benchmark, standardize, and validate senescent cell maps at high resolution.

Technology Development and Application (UG3/UH3 - Clinical Trial Not Allowed): RFA RM-21-009

  • The purpose of this FOA is to solicit projects that will establish proof of principle and validation of the next generation of tools, techniques and methods that can be implemented by the consortium for studying cellular senescence and their Senescence Associated Secretory Phenotype (SASP).

Consortium Organization and Data Coordinating Center (U24 - Clinical Trial Not Allowed): RFA RM-21-010

  • This FOA is to support a Consortium Organization and Data Coordinating Center that will serve as the organizational hub and collect, store, curate, and disseminate all data, metadata, analysis and visualization tools, computational models, and aggregate data generated by the consortium into a searchable database.

Pre-application Webinar: NIH Common Fund staff will host an interactive pre-application webinar to discuss frequently asked questions as well as any other applicant queries on January 22, 2021, from 12:00-1:30pm (EDT). A recording of the webinar will not be posted online, but the slides and resultant Frequently Asked Questions (FAQs) will be posted on the SenNet webpage. Please direct inquiries to
Webinar details are below:
Meeting number: 126 463 3177
Password: Senescence

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Access code: 126 463 3177

About the NIH Common Fund: The NIH Common Fund encourages collaboration and supports a series of exceptionally high-impact, trans-NIH programs. Common Fund programs are managed by the Office of Strategic Coordination in the Division of Program Coordination, Planning, and Strategic Initiatives in the NIH Office of the Director in partnership with the NIH Institutes, Centers, and Offices. More information is available at the Common Fund website:

Last Updated 01/13/2021