Rac1

Nakamura, T., et al. (2017). Novel role of Rac-Mid1 signaling in medial cerebellar development. Development 144(10): 1863-1875. PubMed ID: 28512198

Nakaya, Y., Kuroda, S., Katagiri, Y. T., Kaibuchi, K. and Takahashi Y. (2004). Mesenchymal-epithelial transition during somitic segmentation is regulated by differential roles of Cdc42 and Rac1. Dev Cell. 7(3): 425-38. 15363416

Newsome, T. P., Schmidt, S., Dietzl, G., Keleman, K., Asling, B., Debant, A., and Dickson, B. J. (2000). Trio combines with Dock to regulate Pak activity during photoreceptor axon pathfinding in Drosophila. Cell 101: 283-94. PubMed Citation: 10847683

Ng, J., et al. (2002). Rac GTPases control axon growth, guidance and branching. Nature 416: 442-447. 11919635

Ng, J. and Luo, L. (2004). Rho GTPases regulate axon growth through convergent and divergent signaling pathways. Neuron 44: 779-793. 15572110

Ng, J. (2008). TGF-β signals regulate axonal development through distinct Smad-independent mechanisms. Development 135(24): 4025-35. PubMed Citation: 19004854

Nikolic, M., et al. (1998). The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activity. Nature 395(6698): 194-8. PubMed Citation: 9744280

Nisimoto, Y., et al. (1997). Rac binding to p67(phox). Structural basis for interactions of the Rac1 effector region and insert region with components of the respiratory burst oxidase. J. Biol. Chem. 272(30): 18834-18841. PubMed Citation: 9228059

Nobes, C. D. and Hall, A. (1995a). Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia. Cell 81 (1): 53-62. PubMed Citation: 7536630

Nobes, C. D., et al. (1995b). Activation of the small GTP-binding proteins rho and rac by growth factor receptors. J. Cell Sci. 108 ( Pt 1): 225-233. PubMed Citation: 7738099

Nola, S., et al. (2008). Scrib regulates PAK activity during the cell migration process. Hum. Mol. Genet. 17: 3552-3565. PubMed Citation: 18716323

Nolan, K. M., et al. (1998). Myoblast city, the Drosophila homolog of DOCK180/CED-5, is required in a Rac signaling pathway utilized for multiple developmental processes. Genes Dev. 21: 3337-3342. PubMed Citation: 9808621

Norman, J. C., et al. (1996). The small GTP-binding proteins, Rac and Rho, regulate cytoskeletal organization and exocytosis in mast cells by parallel pathways. Mol Biol Cell 7 (9): 1429-1442. PubMed Citation: 8885237

Obermeier, A., et al. (1998). PAK promotes morphological changes by acting upstream of Rac. EMBO J. 17: 4328-4339. PubMed Citation: 9687501

Olofsson, B. and Page, D. T. (2005). Condensation of the central nervous system in embryonic Drosophila is inhibited by blocking hemocyte migration or neural activity. Dev. Biol. 279(1): 233-43. 15708571

Olson, M. F., Ashworth, A., and Hall, A. (1995). An essential role for Rho, Rac, and Cdc42 GTPases in cell cycle progression through G1. Science 269: 1270-1272. PubMed Citation: 7652575

Ostrowski, D., Kahsai, L., Kramer, E. F., Knutson, P. and Zars, T. (2015). Place memory retention in Drosophila. Neurobiol Learn Mem 123: 217-224. PubMed ID: 26143995

Paglini, G., et al. (1998). Evidence for the participation of the neuron-specific CDK5 activator P35 during laminin-enhanced axonal growth. J Neurosci 18(23): 9858-9869. PubMed Citation: 9822744

Palamidessi, A., et al. (2008). Endocytic trafficking of Rac is required for the spatial restriction of signaling in cell migration. Cell 134(1): 135-47. PubMed Citation: 18614017

Patel, M., Margaron, Y., Fradet, N., Yang, Q., Wilkes, B., Bouvier, M., Hofmann, K. and Cote, J. F. (2010). An evolutionarily conserved autoinhibitory molecular switch in ELMO proteins regulates Rac signaling. Curr Biol 20: 2021-2027. PubMed ID: 21035343

Patrick, G. N., et al. (1998). p35, the neuronal-specific activator of cyclin-dependent kinase 5(Cdk5) is degraded by the ubiquitin-proteasome pathway. J. Biol. Chem. 273(37): 24057-64. PubMed Citation: 9727024

Penzes, P., et al. (2003). Rapid induction of dendritic spine morphogenesis by trans-synaptic EphrinB-EphB receptor activation of the Rho-GEF Kalirin. Neuron 37: 263-274. 12546821

Perona, R., et al. (1997). Activation of the nuclear factor-KB by Rho, CDC42, and Rac-1 proteins. Genes Dev. 11: 463-475. PubMed Citation: 9042860

Perpelescu, M., Nozaki, N., Obuse, C., Yang, H. and Yoda, K. (2009). Active establishment of centromeric CENP-A chromatin by RSF complex. J. Cell Biol. 185: 397-407. PubMed Citation: 19398759

Pirraglia, C., Jattani, R. and Myat, M. M. (2006). Rac function in epithelial tube morphogenesis. Dev. Bio. 290: 435-446. 16412417

Potempa, S. and Ridley, A. J. (1998). Activation of both MAP kinase and Phosphatidylinositide 3-kinase by Ras Is required for Hepatocyte growth factor/Scatter factor-induced adherens junction disassembly. Mol. Biol. Cell 9(8): 2185-2200. PubMed Citation: 9693375

Price, L. S., et al. (1998). Activation of rac and cdc42 by integrins mediates cell spreading. Mol. Biol. Cell 9(7): 1863-1871. PubMed Citation: 9658176

Qi, Z., et al. (1998). Association of neurofilament proteins with neuronal Cdk5 activator. J. Biol. Chem. 273(4): 2329-35. PubMed Citation: 9442078

Qiu, R.-G., Abo, A. and Martin, G. S. (2000). A human homolog of the C. elegans polarity determinant Par-6 links Rac and Cdc42 to PKCzeta signaling and cell transformation. Curr. Biol. 10: 697-707. PubMed Citation: 10873802

Quinn, C. C., Pfeil, D. S. and Wadsworth, W. G. (2008). CED-10/Rac1 mediates axon guidance by regulating the asymmetric distribution of MIG-10/lamellipodin. Curr. Biol. 18(11): 808-13. PubMed Citation: 18499456

Raymond, K., et al. (2004). A screen for modifiers of RacGAP(84C) gain-of-function in the Drosophila eye revealed the LIM kinase Cdi/TESK1 as a downstream effector of Rac1 during spermatogenesis. J. Cell Sci. 117(Pt. 13): 2777-2789. 15169836

Reddien, P. W. and Horvitz, H. R. (2000). CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans. Nat. Cell Biol. 2(3): 131-6. 10707082

Reif, K., et al. (1996). Phosphatidylinositol 3-kinase signals activate a selective subset of Rac/Rho-dependent effector pathways. Curr Biol 6: 1445-1455. PubMed Citation: 8939609

Ricos, M. G., et al. (1999). Dcdc42 acts in TGF-beta signaling during Drosophila morphogenesis: distinct roles for the Drac1/JNK and Dcdc42/TGF-beta cascades in cytoskeletal regulation. J. Cell Sci. 112: 1225-35. PubMed Citation: 10085257

Ridley, A. J. and Hall, A. (1992a). The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors. Cell 70(3), 389-399. PubMed Citation: 1643657

Ridley, A. J., et al. (1992b). The small GTP-binding protein rac regulates growth factor-induced membrane ruffling. Cell 70 (3): 401-410. PubMed Citation: 1643658

Risher, W. C., Kim, N., Koh, S., Choi, J. E., Mitev, P., Spence, E. F., Pilaz, L. J., Wang, D., Feng, G., Silver, D. L., Soderling, S. H., Yin, H. H. and Eroglu, C. (2018). Thrombospondin receptor alpha2delta-1 promotes synaptogenesis and spinogenesis via postsynaptic Rac1. J Cell Biol 217(10): 3747-3765. PubMed ID: 30054448

Roux, P., et al. (1997). The small GTPases Cdc42Hs, rac1 and RhoG delineate raf-independent pathways that cooperate to transform NIH3T3 cells. Curr. Biol. 7(9): 629-637. PubMed Citation: 9285711

Rui, M., Qian, J., Liu, L., Cai, Y., Lv, H., Han, J., Jia, Z. and Xie, W. (2017). The neuronal protein Neurexin directly interacts with the Scribble-Pix complex to stimulate F-actin assembly for synaptic vesicle clustering. J Biol Chem 292(35):14334-14348. PubMed ID: 28710284

Sailem, H., Bousgouni, V., Cooper, S. and Bakal, C. (2014). Cross-talk between Rho and Rac GTPases drives deterministic exploration of cellular shape space and morphological heterogeneity. Open Biol 4: 130132. PubMed ID: 24451547

Saneyoshi, T., et al. (2008). Activity-dependent synaptogenesis: regulation by a CaM-kinase kinase/CaM-kinase I/βPIX signaling complex. Neuron 57(1): 94-107. PubMed citation: 18184567

Santy, L. C., et al. (2005). The DOCK180/Elmo complex couples ARNO-mediated Arf6 activation to the downstream activation of Rac1. Curr. Biol. 15: 1749-1754. PubMed Citation: 16213822

Sanui, T., et al. (2003). DOCK2 regulates Rac activation and cytoskeletal reorganization through interaction with ELMO1. Blood 102: 2948-2950. PubMed Citation: 12829596

Sarkar, A., et al. (2007). Antagonistic roles of Rac and Rho in organizing the germ cell microenvironment. Curr. Biol. 17(14): 1253-8. PubMed citation: 17629483

Schenck, A., Bardoni, B., Langmann, C., Harden, N., Mandel, J. L. and Giangrande, A. (2003). CYFIP/Sra-1 controls neuronal connectivity in Drosophila and links the Rac1 GTPase pathway to the fragile X protein. Neuron 38: 887-898. 12818175

Schreij, A. M., Chaineau, M., Ruan, W., Lin, S., Barker, P. A., Fon, E. A. and McPherson, P. S. (2014). LRRK2 localizes to endosomes and interacts with clathrin-light chains to limit Rac1 activation. EMBO Rep 16(1):79-86. PubMed ID: 25427558

Sells, M. A., Boyd, J. T. and Chernoff, J. (1999). p21-activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts. J. Cell Biol. 145(4): 837-849. PubMed Citation: 10330410

Sepp, K. J. and Auld, V. J. (2003). RhoA and Rac1 GTPases mediate the dynamic rearrangement of actin in peripheral glia. Development 130: 1825-1835. 12642488

Sharma, P., et al. (1998). Site-specific phosphorylation of Lys-Ser-Pro repeat peptides from neurofilament H by cyclin-dependent kinase 5: structural basis for substrate recognition. Biochemistry 37(14): 4759-66. PubMed Citation: 9537991

Shaw, R. J., et al. (2001). The Nf2 tumor suppressor, merlin, functions in rac-dependent signaling. Dev. Cell 1: 63-72. PubMed Citation: 11703924

Shivalkar, M. and Giniger, E. (2012). Control of dendritic morphogenesis by Trio in Drosophila melanogaster. PLoS One 7: e33737. PubMed ID: 22438988

Shuai, Y., Lu, B., Hu, Y., Wang, L., Sun, K. and Zhong, Y. (2010). Forgetting is regulated through Rac activity in Drosophila. Cell 140: 579-589. PubMed ID: 20178749

Shuai, Y., Hu, Y., Qin, H., Campbell, R. A. and Zhong, Y. (2011). Distinct molecular underpinnings of Drosophila olfactory trace conditioning. Proc. Natl. Acad. Sci. 108(50): 20201-6. PubMed Citation: 22123966

Shuang, R., et al. (1998). Regulation of Munc-18/syntaxin 1A interaction by cyclin-dependent kinase 5 in nerve endings. J. Biol. Chem. 273(9): 4957-66. PubMed Citation: 9478941

Sini, P., Cannas, A., Koleske, A. J., Di Fiore, P. P. and Scita, G. (2004). Abl-dependent tyrosine phosphorylation of Sos-1 mediates growth-factor-induced Rac activation. Nat. Cell. Biol. 6: 268-274. 15039778

Skorski, T., et al. (1998). BCR/ABL-mediated leukemogenesis requires the activity of the small GTP-binding protein Rac. Proc. Natl. Acad. Sci. 95(20): 11858-62. PubMed Citation: 9751755

Soba, P., Han, C., Zheng, Y., Perea, D., Miguel-Aliaga, I., Jan, L. Y. and Jan, Y. N. (2015). The Ret receptor regulates sensory neuron dendrite growth and integrin mediated adhesion. Elife 4. PubMed ID: 25764303

Socodato, R., Portugal, C. C., Canedo, T., Rodrigues, A., Almeida, T. O., Henriques, J. F., Vaz, S. H., Magalhaes, J., Silva, C. M., Baptista, F. I., Alves, R. L., Coelho-Santos, V., Silva, A. P., Paes-de-Carvalho, R., Magalhaes, A., Brakebusch, C., Sebastiao, A. M., Summavielle, T., Ambrosio, A. F. and Relvas, J. B. (2020). Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration. Cell Rep 31(12): 107796. PubMed ID: 32579923

Sone, M., et al. (1997). Still life, a protein in synaptic terminals of Drosophila homologous to GDP-GTP exchangers. Science 275(5299): 543-547. PubMed Citation: 9072802

Sone, M., et al. (2000). Synaptic development is controlled in the periactive zones of Drosophila synapses. Development 127: 4157-4168. PubMed Citation: 10976048

Sotillos, S. and Campuzano, S. (2000). DRacGAP, a novel Drosophila gene, inhibits Egfr/Ras signaling in the developing imaginal wing disc. Development 127: 5427-5438.. PubMed Citation: 17032066

Stappenbeck, T. S. and Gordon, J. I. (2000). Rac1 mutations produce aberrant epithelial differentiation in the developing and adult mouse small intestine. Development 127: 2629-2642. PubMed Citation: 10821761

Stappenbeck, T. S. and Gordon, J. I. (2001). Extranuclear sequestration of phospho-Jun N-terminal kinase and distorted villi produced by activated Rac1 in the intestinal epithelium of chimeric mice. Development 128: 2603-2614. 11493576

Steffen, A., Rottner, K., Ehinger, J., Innocenti, M., Scita, G., Wehland, J. and Stradal, T. E. (2004). Sra-1 and Nap1 link Rac to actin assembly driving lamellipodia formation. EMBO J. 23: 749-759. 14765121

Stavoe, A. K., Nelson, J. C., Martinez-Velazquez, L. A., Klein, M., Samuel, A. D. and Colon-Ramos, D. A. (2012). Synaptic vesicle clustering requires a distinct MIG-10/Lamellipodin isoform and ABI-1 downstream from Netrin. Genes Dev 26: 2206-2221. PubMed ID: 23028145

Steven, R., et al. (1998). UNC-73 activates the Rac GTPase and is required for cell and growth cone migrations in C. elegans. Cell 92(6): 785-795. PubMed Citation: 9529254

Storey, N. M., O'Bryan, J. P. and Armstrong, D. L. (2002). Rac and Rho mediate opposing hormonal regulation of the ether-a-go-go-related potassium channel. Curr. Biol. 12: 27-33. 11790300

Struckhoff, E. C. and Lundquist, E. A. (2003). The actin-binding protein UNC-115 is an effector of Rac signaling during axon pathfinding in C. elegans. Development 130: 693-704. 12506000

Su, Y.-C. Treisman, J. E. and Skolnik, E. Y. (1998). The Drosophila Ste20-related kinase misshapen is required for embryonic dorsal closure and acts through a JNK MAPK module on an evolutionarily conserved signaling pathway. Genes Dev. 12: 2371-2380. PubMed Citation: 9694801

Sun, M., Liu, L., Zeng, X., Xu, M., Liu, L., Fang, M. and Xie, W. (2009). Genetic interaction between Neurexin and CAKI/CMG is important for synaptic function in Drosophila neuromuscular junction. Neurosci Res 64(4): 362-371. PubMed ID: 19379781

Tahinci, E. and Symes, K. (2003). Distinct functions of Rho and Rac are required for convergent extension during Xenopus gastrulation. Dev. Biol. 259: 318-335. 12871704

Takahashi, K., et al. (1998). Direct binding between two PDZ domain proteins Canoe and ZO-1 and their roles in regulation of the Jun N-terminal kinase pathway in Drosophila morphogenesis. Mech. Dev. 78(1-2): 97-111. PubMed Citation: 9858699

Takano, H., et al. (1998). The Rho family G proteins play a critical role in muscle differentiation. Mol. Cell. Biol. 18(3): 1580-1589. PubMed Citation: 9488475

Takesono, A., et al. (2004). Requirement for tec kinases in chemokine-induced migration and activation of Cdc42 and Rac. Curr. Biol. 14: 917-922. 15186750

Tang, Y., et al. (1997). Kinase-deficient Pak1 mutants inhibit Ras transformation of Rat-1 fibroblasts. Mol. Cell. Biol. 17: 4454-4464. PubMed Citation: 9234703

Tang, Y., Yu, J. and Field, J. (1999). Signals from the ras, rac, and rho GTPases converge on the pak protein kinase in rat-1 fibroblasts. Mol. Cell. Biol. 19(3): 1881-91. PubMed Citation: 10022875

Taniguchi, K., et al. (2007). D-JNK signaling in visceral muscle cells controls the laterality of the Drosophila gut. Dev. Biol. 311(1): 251-63. PubMed Citation: 17915206

Tapon, N, and Hall, A. (1997). Rho, Rac and Cdc42 GTPases regulate the organization of the actin cytoskeleton. Curr. Opin. Cell Biol. 9: 86-92. PubMed Citation: 9013670

Tapon, N., Nagata, K., Lamarche, N. and Hall, A. (1998). A new rac target POSH is an SH3-containing scaffold protein involved in the JNK and NF-kappaB signalling pathways. EMBO J. 17(5): 1395-404. 9482736

Teramoto, H., et al. (1996). Signaling from the small GTP-binding proteins Rac1 and Cdc42 to the c-Jun N-terminal kinase/stress-activated protein kinase pathway. A role for mixed lineage kinase 3/protein-tyrosine kinase 1, a novel member of the mixed lineage kinase family. J Biol Chem 271 (44): 27225-27228. PubMed Citation: 8910292

Timpson, P., et al. (2001). Coordination of cell polarization and migration by the Rho family GTPases requires Src tyrosine kinase activity. Curr. Biol. 11: 1836-1846. 11728306

Tolias, K. F., Cantley, L. C. and Carpenter, C. L. (1995). Rho family GTPases bind to phosphoinositide kinases. J. Biol. Chem. 270(30): 17656-9. PubMed Citation: 7629060

Tolias, K. F., et al. (1998). Characterization of a Rac1- and RhoGDI-associated lipid kinase signaling complex. Mol. Cell. Biol. 18(2): 762-770. PubMed Citation: 9447972

Tolias, K. F., et al. (2000). Type Ialpha phosphatidylinositol-4-phosphate 5-kinase mediates Rac-dependent actin assembly. Curr. Biol. 10: 153-156. PubMed Citation: 10679324

Tolias, K. F., et al. (2005). The Rac1-GEF Tiam1 couples the NMDA receptor to the activity-dependent development of dendritic arbors and spines. Neuron 45(4): 525-38. 15721239

Tolkacheva, T., et al. (1997). Cooperative transformation of NIH3T3 cells by G alpha12 and Rac1. Oncogene 15(6): 727-735. PubMed Citation: 9264413

Toure, A., et al. (1998). MgcRacGAP, a new human GTPase-activating protein for Rac and Cdc42 similar to Drosophila rotund RacGAP gene product, is expressed in male germ cells. J. Biol. Chem. 273(11): 6019-6023. PubMed Citation: 9497316

Trogden, K. P. and Rogers, S. L. (2015). TOG proteins are spatially regulated by Rac-GSK3β to control interphase microtubule dynamics. PLoS One 10: e0138966. PubMed ID: 26406596

Tunggal, J. A. et al. (2005). E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions. EMBO J. 24: 1146-1156. 15775979

Turner, C. M. and Adler, P. N. (1998). Distinct roles for the actin and microtubule cytoskeletons in the morphogenesis of epidermal hairs during wing development in Drosophila. Mech. Dev. 70(1-2): 181-192. PubMed Citation: 9510034

Tzou, F. Y., Su, T. Y., Lin, W. S., Kuo, H. C., Yu, Y. L., Yeh, Y. H., Liu, C. C., Kuo, C. H., Huang, S. Y. and Chan, C. C. (2021). Dihydroceramide desaturase regulates the compartmentalization of Rac1 for neuronal oxidative stress. Cell Rep 35(2): 108972. PubMed ID: 33852856

Um, K., Niu, S., Duman, J. G., Cheng, J. X., Tu, Y. K., Schwechter, B., Liu, F., Hiles, L., Narayanan, A. S., Ash, R. T., Mulherkar, S., Alpadi, K., Smirnakis, S. M. and Tolias, K. F. (2014). Dynamic control of excitatory synapse development by a Rac1 GEF/GAP regulatory complex. Dev Cell 29: 701-715. PubMed ID: 24960694

Van Aelst, L., Joneson, T. and Bar-Sagi, D. (1996). Identification of a novel Rac1-interacting protein involved in membrane ruffling. EMBO J 15 (15): 3778-3786. PubMed Citation: 8670882

Vanderzalm, P. J., et al. (2009). C. elegans CARMIL negatively regulates UNC-73/Trio function during neuronal development. Development 136(7): 1201-10. PubMed Citation: 19244282

van Impel, A., et al. (2009). Regulation of the Rac GTPase pathway by the multifunctional Rho GEF Pebble is essential for mesoderm migration in the Drosophila gastrula. Development 136(5): 813-22. PubMed Citation: 19176590

van Leeuwen, F. N., et al. (1999). Rac regulates phosphorylation of the myosin-II heavy chain, actinomyosin disassembly and cell spreading. Nat. Cell Biol. 1: 242-248. PubMed Citation: 10559923

Veltman, D. M. and Insall, R. H. (2010). WASP family proteins: their evolution and its physiological implications. Mol Biol Cell 21: 2880-2893. PubMed ID: 20573979

Vikis, H. G., Li, W. and Guan, K.-L. (2002). The Plexin-B1/Rac interaction inhibits PAK activation and enhances Sema4D ligand binding. Genes Dev. 16: 836-845. 11937491

Vincent, S., Settleman, J. (1997). The PRK2 kinase is a potential effector target of both Rho and Rac GTPases and regulates actin cytoskeletal organization. Mol. Cell. Biol. 17 (4): 2247-2256. PubMed Citation: 9121475

Wada, Y., et al. (1998). Microtubule-stimulated phosphorylation of tau at Ser202 and Thr205 by cdk5 decreases its microtubule nucleation activity. J. Biochem. (Tokyo) 124(4): 738-746. PubMed Citation: 9756618

Wan, P., Wang, D., Luo, J., Chu, D., Wang, H., Zhang, L. and Chen, J. (2013). Guidance receptor promotes the asymmetric distribution of exocyst and recycling endosome during collective cell migration. Development 140(23): 4797-806. PubMed ID: 24198275

Waterman-Storer, C. M. (1999). Microtubule growth activates Rac1 to promote lamellipodial protrusion in fibroblasts. Nat. Cell Biol. 1: 45-50. PubMed Citation: 10559863

Weed, S. A., Du, Y. and Parsons, J. T. (1998). Translocation of cortactin to the cell periphery is mediated by the small GTPase Rac1. J. Cell Sci. 111( Pt 16): 2433-2443. PubMed Citation: 9683637

Wegmeyer, H., et al. (2007). EphA4-dependent axon guidance is mediated by the RacGAP α2-Chimaerin. Neuron. 55: 756-767. Medline abstract: 17785182

Wellington, A., et al. (1999). Spire contains actin binding domains and is related to ascidian posterior end mark-5. Development 126: 5267-5274. PubMed Citation: 10556052

Werner, L. A. and Manseau, L. J. (1997). A Drosophila gene with predicted rhoGEF, a pleckstrin homology and SH3 domains is highly expressed in morphogenic tissues. Gene 187: 107-114. PubMed Citation: 9073073

West, M. A., et al. (2000). Rac is required for constitutive macropinocytosis by dendritic cells but does not control its downregulation. Curr. Biol. 10: 839-848. PubMed Citation: 10899002

Weston, C., et al. (2000). Agrin-induced Acetylcholine receptor clustering is mediated by the small guanosine triphosphatases Rac and Cdc42. J. Cell Bio. 150: 205-212. 10893268

Wong, L. and Adler, P. (1993). Tissue polarity genes of Drosophila regulate the subcellular loation of prehair initiation in pupal wing cells. J. Cell Biol. 123: 209-221. PubMed Citation: 8408199

Wu, Y. C. and Horvitz, H. R. (1998). C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180. Nature 392: 501-504. PubMed Citation: 9548255

Wu, Y.-C., et al. (2002). Distinct Rac activation pathways control Caenorhabditis elegans cell migration and axon outgrowth. Dev. Bio. 250: 145-155. 12297102

Wu, Y. I., et al. (2009). A genetically encoded photoactivatable Rac controls the motility of living cells. PubMed Citation: 19693014

Xavier, M. J. and Williams, M. J. (2011). The Rho-family GTPase Rac1 regulates integrin localization in Drosophila immunosurveillance cells. PLoS One 6(5): e19504. PubMed Citation: 21603603

Xu, Y. and Quinn, C. C. (2012). MIG-10 functions with ABI-1 to mediate the UNC-6 and SLT-1 axon guidance signaling pathways. PLoS Genet 8: e1003054. PubMed ID: 23209429

Xu, Z., Kukekov, N. V. and Greene, L. A. (2003). POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis. EMBO J. 22(2): 252-61. 12514131

Yang, L. and Bashaw, G. J. (2006). Son of sevenless directly links the Robo receptor to rac activation to control axon repulsion at the midline. Neuron 52(4): 595-607. Medline abstract: 17114045

Yang, N., et al. (1998). Cofilin phosphorylation by LIM-kinase 1 and its role in Rac-mediated actin reorganization. Nature 393: 809-812. PubMed Citation: 9655398

Yang, Q., Zhou, J., Wang, L., Hu, W., Zhong, Y. and Li, Q. (2023). Spontaneous recovery of reward memory through active forgetting of extinction memory. Curr Biol. PubMed ID: 36731465

Zhang, H., Webb, D. J., Asmussen, H., Niu, S., and Horwitz, A. F. (2005) A GIT1/PIX/Rac/PAK signaling module regulates spine morphogenesis and synapse formation through MLC. J. Neurosci. 25, 3379-3388. PubMed ID: 15800193

Zhang, S., et al. (1995). Rho family GTPases regulate p38 mitogen-activated protein kinase through the downstream mediator Pak1. J. Biol. Chem. 270 (41): 23934-23936. PubMed Citation: 7592586

Zhang, Y., Chen, K., Tu, Y. and Wu, C. (2004). Distinct roles of two structurally closely related focal adhesion proteins, alpha-parvins and beta-parvins, in regulation of cell morphology and survival. J. Biol. Chem. 279(40): 41695-705. 15284246

Zhao, Z. S., et al. (1998). A conserved negative regulatory region in alphaPAK: inhibition of PAK kinases reveals their morphological roles downstream of Cdc42 and Rac1. Mol. Cell. Biol. 18(4): 2153-2163. PubMed Citation: 9528787

Zheng, M., Leung, C. L. and Liem, R. K. (1998). Region-specific expression of cyclin-dependent kinase 5 (cdk5) and its activators, p35 and p39, in the developing and adult rat central nervous system. J. Neurobiol. 35(2): 141-59. PubMed Citation: 9581970

Zhou, G. L. et al. (2006). Opposing roles for Akt1 and Akt2 in Rac/Pak signaling and cell migration. J. Biol. Chem. 281: 36443-36453. PubMed Citation: 17012749

Zhou, Q., et al. (2010). 14-3-3 coordinates microtubules, Rac, and myosin II to control cell mechanics and cytokinesis. Curr Biol. 20(21): 1881-9. PubMed Citation: 20951045

Zhou, Z., et al. (2001). The C. elegans PH domain protein CED-12 regulates cytoskeletal reorganization via a Rho/Rac GTPase signaling pathway. Dev. Cell 1: 477-489. 11703939

Return: Rac References part 1/2

date revised:   5 October 2020
 

Home page: The Interactive Fly © 1997 Thomas B. Brody, Ph.D.

The Interactive Fly resides on the
Society for Developmental Biology's Web server.