Rac1

EVOLUTIONARY HOMOLOGS
Table of Contents

page 1

The Rac and Rho family of GTPases
Rac2 in Drosophila
Activation of Rac
RAC GTPase-activating proteins (GAPs)
Regulation of Rho GTPases by crosstalk

page 2

Proteins interacting with Rac: Rac GEFs
Proteins interacting with Rac: RAC GTPase-activating proteins (GAPs)

page 3

Proteins interacting with Rac: PAK

page 4

Proteins interacting with Rac: PI 3-kinase
Proteins interacting with Rac: DOCK180

page 5

Proteins interacting with Rac: Cdk5
Rac interacts with a protein complex involved in the generation of reactive oxygen species
Other signaling upstream of Rac

page 6

Microtubules interact with Rac
Miscellaneous proteins interacting with Rac
Rac pathway targets JNK

page 7

Sra-1 and Nap1 link Rac and Nck to actin assembly driving lamellipodia formation
SCAR/WAVE functions downstream of Rac signaling
A Trio-Rac1-Pak1 signalling axis drives invadopodia disassembly
Epithelial cell-cell contacts regulate SRF-mediated transcription via Rac-actin-MAL signalling
The SWI/SNF protein BAF60b is ubiquitinated through a signalling process involving Rac GTPase and the RING finger protein Unkempt
Other downstream targets and components of Rac signaling
Rac involvement in adhesion, cell spreading, and cell migration
Rac and cell cycle progression
Rac regulates meiotic spindle stability and anchoring in mammalian oocytes

page 8

Rac and cytoskeletal rearrangement
Rac and cell polarity
Rac and cerebellar development
Rac and axon guidance
Rac and synapses
Rac and junctions
Rac and differentiation
Rac and apoptosis
Rac and photoreceptor response
Rac and learning, memory and forgetting
Rac and cellular oncogenic transformation

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