The Interactive Fly

Genes involved in tissue and organ development Genes expressed in eye morphogenesis Genes expressed in antennal morphogenesis Bolwig's Organ, the Hofbauer-Buchner Eyelet and Ocelli Structure of the eye Development of the eye Image: Specification of the eye disc primordium and establishment of dorsal/ventral asymmetry Eye-antenna disc Specification of the eye versus the antenna 5D imaging via light sheet microscopy reveals cell dynamics during the eye-antenna disc primordium formation in Drosophila Transformation of eye to antenna by misexpression of a single gene Genes expressed in antennal differentiation Notch-dependent epithelial fold determines boundary formation between developmental fields in the Drosophila antenna Identification of genomic enhancers through spatial integration of single-cell transcriptomics and epigenomics Avalanches during epithelial tissue growth; Uniform Growth and a Drosophila eye disc model Eye development The Drosophila Adult Ommatidium Atonal and EGFR signalling orchestrate rok- and Drak-dependent adherens junction remodelling during ommatidia morphogenesis Mapping gene regulatory networks in Drosophila eye development by large-scale transcriptome perturbations and motif inference Stochastic spineless expression creates the retinal mosaic for colour vision Binary cell fate decisions and fate transformation in the Drosophila larval eye The spatiotemporal order of signaling events unveils the logic of development signaling Single-base pair differences in a shared motif determine differential Rhodopsin expression Polycomb group genes are required to maintain a binary fate choice in the Drosophila eye Wingless mediated apoptosis: How cone cells direct the death of peripheral ommatidia in the developing Drosophila eye Proteasome, but not autophagy, disruption results in severe eye and wing dysmorphia: a subunit- and regulator-dependent process in Drosophila A population of G2-arrested cells are selected as sensory organ precursors for the interommatidial bristles of the Drosophila eye The mir-279/996 cluster represses receptor tyrosine kinase signaling to determine cell fates in the Drosophila eye The phosphoinositide phosphatase Sac1 regulates cell shape and microtubule stability in the developing Drosophila eye Cellular homeostasis in the Drosophila retina requires the lipid phosphatase Sac1 Lipidome unsaturation affects the morphology and proteome of the Drosophila eye Motif 1 Binding Protein suppresses wingless to promote eye fate in Drosophila Buffered EGFR signaling regulated by spitz-to-argos expression ratio is a critical factor for patterning the Drosophila eye Herzog is not required for mushroom body development or courtship learning & memory but is required for eye development in Drosophila melanogaster Cell Cycle Regulation by NF-YC in Drosophila Eye Imaginal Disc: Implications for Synchronization in the Non-Proliferative Region Peripodial adherens junctions regulate Ajuba-Yorkie signaling to preserve fly eye morphology A deficiency screen of the 3rd chromosome for dominant modifiers of the Drosophila ER integral membrane protein, Jagunal Medioapical contractile pulses coordinated between cells regulate Drosophila eye morphogenesis Photoreceptors The actomyosin machinery is required for Drosophila retinal lumen formation Ire1 supports normal ER differentiation in developing Drosophila photoreceptors Past1 modulates Drosophila eye development Cell surface molecule, Klingon, mediates the refinement of synaptic specificity in the Drosophila visual system Integrins are required for synchronous ommatidial rotation in the Drosophila eye linking planar cell polarity signalling to the extracellular matrix Nonsynaptic Transmission Mediates Light Context-Dependent Odor Responses in Drosophila melanogaster Exploring the molecular makeup of support cells in insect camera eyes Drosophila Phosphatase of Regenerating Liver Is Critical for Photoreceptor Cell Polarity and Survival during Retinal Development Blimp-1/PRDM1 and Hr3/RORβ specify the blue-sensitive photoreceptor subtype in Drosophila by repressing the hippo pathway Orthogonal coupling of a 3D cytoskeletal scaffold coordinates cell morphogenesis and maintains tissue organization in the Drosophila pupal retina Establishing the contribution of active histone methylation marks to the aging transcriptional landscape of Drosophila photoreceptors Identification of genes regulating stimulus-dependent synaptic assembly in Drosophila using an automated synapse quantification system Transcriptional Feedback Links Lipid Synthesis to Synaptic Vesicle Pools in Drosophila Photoreceptors Glia Exploring the molecular makeup of support cells in insect camera eyes Vision Contribution of photoreceptor subtypes to spectral wavelength preference in Drosophila Color discrimination with broadband photoreceptors Genetic dissection reveals two separate retinal substrates for polarization vision in Drosophila Identifying functional connections of the inner photoreceptors in Drosophila using Tango-Trace Loss of Na/K-ATPase in Drosophila photoreceptors leads to blindness and age-dependent neurodegeneration Proteins involved in visual signal transduction Anatomical reconstruction and functional imaging reveal an ordered array of skylight polarization detectors in Drosophila Circuit mechanisms underlying chromatic encoding in Drosophila photoreceptors

Progression of the morphogenetic furrow across the eye disc

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