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- Wednesday, June 7
- Meeting Registration: 1-5 PM
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- Education Symposium:Improving Science Teaching, 2-5 PM
Chair: Richard Nuccitelli (SDB Education Committee Chair)
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2:00 |
The Science Squad: University Scientists in K-12 Classrooms. J. Graf., S. Messier, D. McDonough, A. Monterossa. Hughes Initiative, Univ. of Colorado, Boulder. |
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2:35 |
Placing undergraduate science majors in K-12 classrooms: teaching to learn and learning to teach. R. Nuccitelli. UC Davis. |
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3:00 |
Break |
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3:20 |
Research experiences for K-12 teachers and classroom implementation. S. Oppenheimer. Cal. State Northridge. |
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3:50 |
Improving undergraduate science education. Y. Cruz and S. Singer. Oberlin Col., Carleton Col. and Natl. Sci. Fndn. |
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4:20 |
Discussion groups: How these changes can be accomplished at your institution |
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Opening Reception: 5:30-7 PM
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- Thursday, June 8, The origins of embryonic patterning
- Meeting Registration: 8 AM-5 PM
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- Funding Opportunities in Developmental Biology, 8-9 AM
Moderator: Ida Chow (SDB)
- Presentations by representatives of Federal and private funding gencies: NSF, NIH, NASA, March of Dimes Birth Defects Foundation
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Plenary Session I The Origins of Embryonic Patterning, 9:00-11:00 AM
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9:00 |
Is there a germ line determinant? Ruth Lehmann. HHMI and Skirball Inst., NYU Med. Ctr. |
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9:30 |
Development of polarity in the oocyte. Allan C. Spradling. Carnegie Inst. of Washington, Baltimore. |
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10:00 |
TGF-beta signaling pathways controlling polarity of the early mouse embryo. Elizabeth J. Robertson. Harvard Univ. |
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10:30 |
Origins of pattern in plants. Kathy Barton. Univ. of Wisconsin, Madison. |
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11:00-11:30 AM |
Break |
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- Parallel Symposia 1-3, 11:30 AM-4:00 PM
- Talks by invited speakers (30 min) and selections from contributed abstracts (15 min), with lunch break 12:30-2 P.M.
- * - Presenting author of contributed abstracts
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- Symposium 1: Maternal Determinants, 11:30 A.M.-4:00 P.M.
Chair: Ruth Lehmann
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11:30 |
Mitotic spindle orientation during asymmetric cell divisions in the early C. elegans embryo. Bruce Bowerman. Univ. of Oregon. |
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12:00 |
Establishment of Drosophila embryonic polarity by RNA localization and translational control. Anne Ephrussi. EMBL, Heidelberg, Germany. |
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12:30 |
Lunch |
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2:00 |
The C. elegans gene nos-2, required for germline development, encodes a P granule associated mRNA that may be regulated at the translational level. Kuppuswamy Subramaniam* and G. Seydoux. Johns Hopkins Univ. Sch. of Med. |
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2:15 |
Zebrafish vasa RNA but not its protein is a component of the germ plasm and segregates asymmetrically prior to germ-line specification. Holger. Knaut*, F. Pelegri, K. Bohmann, H. Schwarz and C. Nüsslein-Volhard,. Max-Planck Institut für Entwicklungsbiologie, Tübingen, Germany. |
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2:30 |
Maternal cytoplasmic information and cell specification in the ascidian embryo. N. Satoh. Kyoto Univ., Japan. |
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3:00 |
Germ plasm components XDAZL, XCAT2, and DEADSouth are required for primordial germ cell formation in Xenopus. Mary Lou King*, D.W. Houston and M. Mora. Univ. Miami Sch. of Med. |
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3:15 |
The putative Wnt receptor Xenopus frizzled-7 is required for vertebrate axis induction. Saulius Sumanas*, P. Strege, J. Heasman and S.C. Ekker. Univ. of Minnesota. |
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3:30 |
Patterning by Nodal signals. A. Schier. New York Univ. |
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- Symposium 2: Oocyte and Egg Polarity, 11:30 A.M.-4:00 P.M.
Chair: Allan Spradling
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11:30 |
Polarity and patterning in early embryogenesis of Arabidopsis. Gerd J�rgens. T�bingen Univ., Germany. |
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12:00 |
DWnt-4 provides two functions during Drosophila ovarian development and oogenesis. Elizabeth L. Wilder* and R.H. Wallace. Univ. of Pennsylvania Sch. of Med. |
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12:15 |
The alphaBbetaC integrin is expressed on the surface of the sea urchin egg and removed at fertilization. Robert D. Burke*, G. Murray, C. Reed, M. Marsden, M. Rise and D. Wang. Univ. of Victoria, Canada. |
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12:30 |
Lunch |
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2:00 |
Distal tip cell control of germline stem cells in C. elegans. Judith Kimble. Univ. of Wisconsin, Madison. |
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2:30 |
Embryonic polarity and asymmetric division in C. elegans. Bob Goldstein. Univ. of North Carolina-Chapel Hill. |
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3:00 |
A genetic pathway for control of embryonic polarity in C. elegans. Craig P. Hunter* and A. Kay. Harvard Univ. |
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3:15 |
A role for microtubules in the establishment of anterior/posterior polarity in C. elegans. Matthew R. Wallenfang* and G. Seydoux. Johns Hopkins Univ. Sch. of Med. |
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3:30 |
Par-1 and polarity in Drosophila. Daniel St. Johnson. Univ. of Cambridge, UK. |
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- Symposium 3: Origin of Polarity in Mouse and Other Non-Polar Systems, 11:30 A.M.-4:00 P.M.
Chair: Elizabeth J. Robertson
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11:30 |
Early asymmetry and development of polarity in the mouse embryo. Magdalena Zernicka-Goetz. Univ. of Cambridge, U.K. |
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12:00 |
The mesoderm development gene is essential for establishing A/P polarity and maintaining early patterning in the mouse embryo. M. Wines, C. DeRossi, K. Brown, S. Wefer and Bernadette Holdener*. SUNY at Stony Brook. |
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12:15 |
Induction of the mammalian node and derivative tissues requires the function of the novel RING domain gene Arkadia. Vasso Episkopou*, R. Arkell, P. Timmons, J. Walsh and D. Swan. MRC Clin. Sci. Ctr., London, MRC, Harwell and Univ. of Edinburgh, U.K. |
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12:30 |
Lunch |
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2:00 |
Symmetry breaking in the chick embryo. Claudio D. Stern. Columbia Univ. |
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2:30 |
Multiple pathways in the midline regulate concordant brain, heart and gut left-right asymmetry. Brent W. Bisgrove*, J.J. Essner and H.J. Yost. Univ. of Utah. |
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2:45 |
The oak ridge polycystic kidney disease gene is required for left-right axis determination. Noel S. Murcia*, W.G. Richards, B.K. Yoder, M.L. Mucenski, J.R. Dunlap and R.P. Woychik. Case Western Reserve Univ., Amgen, Inc., Univ. of Alabama, Birmingham, Children's Hosp. Med. Ctr., Cincinnati, Univ. of Tennessee and Parke-Davis Lab. for Molec. Genet. |
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3:00 |
Identifying genes involved in pattern formation using Arabidopsis genetraps. Andrew T. Groover* and R.M. Martienssen. Cold Spring Harbor Lab. |
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3:15 |
The cloning of a novel candidate gene for the Amnionless mutation. Sundeep Kalantry*, S. Manning, C. Tomihara-Newberger, O. Haub, H-G. Lee, K. Manova and E. Lacy. Mem. Sloan-Kettering Cancer Ctr. |
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3:30 |
Embryonic polarity, asymmetric division, and cell fate determination in Volvox. David L. Kirk. Washington Univ., St. Louis. |
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- Workshops 1 and 2, 7:00-9:00 P.M.
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Workshop 1: Career Options for the Ph.D. Biologist
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Chair:
Richard Nuccitelli
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7:00 |
Teaching AND research at a liberal arts college?! Y. Cruz. Oberlin Col. |
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7:30 |
From codons to concepts: science writing and editing. P. Hines. AAAS/Science. |
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8:00 |
Life outside academia: biology in the business world. R. Lundquist. Law Firm of Fish & Richardson, P.C. |
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8:30 |
High school teaching as a rewarding career option. A. Monterrosa. Manual High School |
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Workshop 2: Advanced Technologies in Biology
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Chair:
Lee Niswander
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7:00 |
In vivo applications of electroporation. L. Niswander. HHMI and Sloan-Kettering Inst., NY. |
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7:20 |
Developing a neurovascular relationship. Damien Bates*, D.F. Newgreen and G.I. Taylor. Royal Children's Hosp., Parkville, Australia and Jack Brockhoff Inst., RMH, Melbourne, Australia. |
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7:40 |
Two lineage boundaries and En1 coordinate AER formation. Alexandra L. Joyner. HHMI, Skirball Inst., New York Univ. Sch. of Med. |
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8:00 |
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8:15 |
Too much interference: injection of double stranded RNA does not have specific effects in the zebrafish embryo. Robert K. Ho. Princeton Univ. |
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8:30 |
Open forum on RNA interference in vertebrates and invertebrates -- successes, problems and controversies |
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- Parallel Symposia 4-6 11:30 AM-4:00 PM
- Talks by invited speakers (30 min) and selections from contributed abstracts (15 min), with lunch break 12:30-2 P.M.
- * - Presenting author of contributed abstracts
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- Symposium 4: Transcriptional Regulation, 11:30 A.M.-4:00 P.M.
Chair:
Mike Levine
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11:30 |
RNA-based information superhighway in plants. Bill J. Lucas. UC Davis. |
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12:00 |
Encoding regulatory information processing in development. Eric Davidson. Caltech. |
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12:30 |
Lunch |
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2:00 |
Ordered assembly of the MSL dosage compensation complex at roX RNA genes and subsequent spreading into flanking chromatin. Rick Kelley. Baylor Col. of Med. |
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2:25 |
Creating endoderm and mesoderm in C. elegans. Joel H. Rothman. UC Santa Barbara. |
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2:50 |
The TBP-like factor CeTLF is required to activate RNA polymerase II transcription during C. elegans embryogenesis. Linda S. Kaltenbach*, M.A. Horner and S.E. Mango. Univ. of Utah. |
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3:05 |
Initial transcriptional regulators of cell fates in the sea urchin embryo. E.W. Howard, A.P. Kenny, L.A. Newman, D.J. Oleksyn, R.C. Angerer and Lynne M. Angerer*. Univ. Rochester. |
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3:20 |
Hey genes form a novel family of Notch target genes with Hey2 as an independent component of the somitogenesis clock. Manfred Gessler*, M. Maier, C. Steidl, A. Fischer, K. Dale, O. Pourquié and C. Leimeister. Univ. of Wurzburg, Germany. |
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3:35 |
Signaling and transcriptional control of pituitary development. Geoff Rosenfeld. UCSD. |
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- Symposium 5: Cell Signaling, 11:30 A.M.-4:00 P.M.
Chair: Gail Martin
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11:30 |
Signaling pathway establishing left-right asymmetry. Hiroshi Hamada. Osaka Univ., Japan. |
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12:00 |
Casein kinase I transduces Wnt signals. John Peters*, R. McKay, J. McKay and J. Graff. Univ. of Texas Southwestern Med. Ctr. |
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12:15 |
Fgf8 is required for patterning of the cranial neural crest. Henry Roehl* and C. Nüsslein-Volhard. Max-Planck-Inst., Tübingen. |
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12:30 |
Lunch |
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2:00 |
Bioactive lipid signaling and cell migration during vertebrate development. Didier Stainier. UCSF. |
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2:30 |
Does T (Brachyury) play a role in limb development? Chunqiao Liu*, S. Hunter, V. Knezevic, K. Thompson and S. Mackem. NCI, NIH. |
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2:45 |
SHH is necessary for cell survival in both the neural tube and paraxial mesoderm in the early avian embryo. Jean-Baptiste Charrier*, M-A. Teillet and N.M. Le Douarin. CNRS FRE, France. |
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3:00 |
Cell architecture in Drosophila: signalling, polarity, and tumor supressors. David Bilder. Harvard Med. Sch. |
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3:30 |
Molecular aspects of cell signaling by chordin. Eddy de Robertis. UCLA. |
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- Symposium 6: Cell Motility and Guidance, 11:30 A.M.-4:00 P.M.
Chair: Corey Goodman
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11:30 |
Developmental regulation of cell motility. Denise Montell. Johns Hopkins Univ. |
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12:00 |
Differentiation-induced changes in trophoblast cell motility and cytoskeleton. Sean Aeder*, M. Parast and A. Sutherland. Univ. of Virginia. |
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12:15 |
One-eyed pinhead dependent cell motility in the zebrafish blastula. Rachel M. Warga* and D.A. Kane. Univ. of Rochester. |
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12:30 |
Lunch |
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2:00 |
Eph receptor activation triggers the assembly of actin structures via Rho family GTPases. Catherine D. Nobes. Univ. College London, U.K. |
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2:30 |
Molecular mechanisms of axon guidance in C. elegans. Joe Culotti. SLRI, Canada. |
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3:00 |
Axon guidance in the periphery. J. Eberhart, M. Swartz, M. Ekong, S.A. Koblar, E.B. Pasquale and Catherine E. Krull*. Univ. of Missouri-Columbia, Univ. of Adelaide, and The Burnham Inst. |
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3:15 |
Roles of the leech rPTP HmLAR2 in growth cone collapse and self-avoidance. Eduardo R. Macagno* and M.W. Baker. Columbia Univ. |
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3:30 |
Shot coordinates actin and microtubule dynamics during neuronal and tracheal morphogenesis. S. Lee and Peter Kolodziej*. HHMI and Vanderbilt Univ. Med. Ctr. |
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3:45 |
Study the function of mouse slit genes. Wenlin Yuan* and D.M. Ornitz. Washington Univ. |
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- Workshops 3 and 4, 7:00-9:00 P.M.
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Workshop 3: Genomics/Proteomics/Informatics
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Co-chairs:
Stuart Kim and Joe Ecker
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7:00 |
Genes blossom from a weed: the Arabidopsis genome initiative. Joe Ecker. Univ. of Pennsylvania. |
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7:30 |
C. elegans functional genomics: profiling gene expression patterns with DNA microarrays. Stuart K. Kim. Stanford Univ. |
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8:00 |
Protein interaction mapping in C. elegans. Marc Vidal. Harvard Univ. |
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8:20 |
Functional genomics: from David to Goliath. Julie Baker. Stanford Univ. |
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8:40 |
Probing the expressed genome of Arabidopsis for protein localization information in a live, multicellular context. David Ehrhardt. Stanford Univ. |
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Workshop 4: Regeneration
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Co-chairs: Alejandro Sanchez Alvarado and Brigitte Galliot
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7:00 |
Early genetic regulations during hydra regeneration. Brigitte Galliot. Univ. of Geneva, Switzerland. |
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7:25 |
Planarian regeneration: revisiting a classic problem using modern methodologies. Phillip A. Newmark*, S. Saha, R. Juste and A. S�nchez Alvarado. Carnegie Inst. of Washington, Baltimore. |
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7:40 |
A serum activity that induces cell cycle re-entry from the differentiated state. Elly M. Tanaka. Max Planck Inst. for Molec. Cell Biol, Germany. |
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8:05 |
Plasticity of postmitotic myotubes in adult regeneration. Anoop Kumar*, C.P. Velloso and J.P. Brockes. Univ. Col. London, U.K. |
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8:20 |
Molecular mechanisms of zebrafish fin regeneration. Alexei Nechiporuk, K. Poss, S. Johnson and M. Keating. Univ. of Utah and HHMI and Washington Univ. Sch. of Med. |
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8:35 |
Metazoan regeneration. Alejandro Sanchez Alvarado. Carnegie Inst. of Washington, Baltimore. |
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- Parallel Symposia 7-9 11:30 AM-4:00 PM
- Talks by invited speakers (30 min) and selections from contributed abstracts (15 min), with lunch break 12:30-2 P.M.
- * - Presenting author of contributed abstracts
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- Symposium 7: Ectodermal Organs, 11:30 A.M.-4:00 P.M.
Chair: Thomas Jessell
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11:30 |
Genetic control of developmental timing in C. elegans. Victor Ambros. Dartmouth Univ. |
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12:00 |
Compartments, boundaries, and signaling in the wing of Drosophila. Seth Blair. Univ. of Wisconsin, Madison. |
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12:30 |
Lunch |
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2:00 |
Genetic analysis of forebrain patterning in zebrafish. Steve W. Wilson. Univ. Col. London, U.K. |
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2:30 |
Formation of the zona limitans intrathalamica: a putative diencephalic organizer. Lori M. Zeltser*, C.W. Larsen, A. Hornbruch and A.G.S. Lumsden. Columbia Univ. and King's Col. London, U.K. |
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2:45 |
Notch activation instructs rapid glial differentiation by multipotent neural crest stem cells. Sean J. Morrison*, S.E. Perez, J.M. Verdi, C. Hicks, G. Weinmaster and D.J. Anderson. Univ. of Michigan, Caltech, UCLA and Univ. of Western Ontario, Canada. |
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3:00 |
Characterization of neural stem cells in the adult mammalian brain. Jonas Frisen. Karolinska Inst., Sweden. |
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3:30 |
Beauty is skin deep: mechanisms of growth and differentiation in the skin. Elaine Fuchs. Univ. of Chicago. |
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- Symposium 8: Mesodermal Organs 11:30 A.M.-4:00 P.M.
Chair: Mark Fishman
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11:30 |
Dissecting ventral mesoderm and hematopoietic development using the Zebrafish. Leonard Zon. Harvard Univ. |
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12:00 |
Notch signalling and the synchronisation of the somite segmentation clock. Yun-Jin Jiang*, L. Smithers, B. Aerne, C. Haddon, D. Ish-Horowicz and J. Lewis. Imperial Cancer Res. Fund, U.K. |
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12:15 |
Mutation of the Tg737 gene reveals an important role in the development and patterning of the mammalian embryo. Bradley K. Yoder*, P.D. Taulman, C.J. Haycraft, S.M. Krum, N.S. Murcia, W.G. Richards and R.P. Woychik. Univ. of Alabama at Birmingham, Case Western Reserve Univ., Amgen and Parke-Davis Lab. for Molec. Genet. |
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12:30 |
Lunch |
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2:00 |
The early steps of development of the hemopoietic and vascular systems in the avian embryo. Nicole Le Douarin. CNRS, France. |
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2:30 |
Co-ordination of early kidney development by Wnt signaling. SeppoVainio. Univ. of Oulu, Finland. |
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3:00 |
Murine Hox11 paralogs are required for metanephric kidney development. Deenen M. Wellik* and M.R. Capecchi. Univ. of Utah. |
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3:15 |
Notch and serrate specify cell fates in the Xenopus heart field. Melissa S. Rones*, K.A. McLaughlin and M. Mercola. Harvard Med Sch. |
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3:30 |
Control of heart and limb development by dHAND. Eric Olson. Univ. Texas Southwestern Med. Ctr. |
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- Symposium 9: Endodermal 11:30 A.M.-4:00 P.M.
Chair: Doug Melton
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11:30 |
Development of the C. elegans intestine. Jim D. McGhee. Univ. of Calgary. |
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12:00 |
Zygotic functions of pal-1, the C. elegans caudal homolog, in posterior embryonic patterning. Lois G. Edgar* and W.B. Wood. Univ. of Colorado. |
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12:15 |
Coordinate signaling by two BMPs in the regional specification of the Drosophila endoderm. Kristi A. Wharton*, C. Savery and R.P. Ray. Brown Univ. |
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12:30 |
Lunch |
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2:00 |
From simple to complex: endoderm formation and embryonic patterning in Xenopus. Janet Heasman. Univ. of Minnesota. |
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2:30 |
Hedgehog signaling in morphogenesis of the gut and a gut derivative. Andy McMahon. Harvard U |
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3:00 |
Anterior endoderm specification and the development of taste buds. Linda A. Barlow*. Univ. of Denver. |
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3:15 |
Controlled differentiation of human embryonic stem cells. Meri T. Firpo*, J.J. Meneses, J. Wu and R.A. Pedersen. UCSF. |
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