shaggy

EVOLUTIONARY HOMOLOGS
Table of Contents

page 1

Plant Shaggy homologs
Shaggy homologs in C. elegans
Multiple Wnt signaling pathways converge to orient the mitotic spindle in early C. elegans embryos:
        GSK-3 functions downstream of three Dishevelled homologs
Other invertebrate Shaggy homologs
Regulation of GSK-3ß
GSK-3ß position in the Wnt pathway
Axin and GSK3-β control Smad3 protein stability and modulate TGF-β signaling
GSK-3ß and the insulin pathway
The endosomal protein Appl1 mediates Akt substrate specificity towards GSK3-β

page 2

GSK-3ß in Fish
GSK-3ß in Xenopus
Signaling downstream of mammalian GSK-3ß

page 3

GSK-3ß, APC and Axin
Crystal structure of Glycogen synthase kinase 3ß

page 4

GSK-3ß targets Dishevelled in neurons
GSK-3ß targets gamma secretase
Other GSK-3ß interactions
GSK-3ß and photoperiod response
GSK-3ß and adipogenesis
GSK-3ß and osteoblast lineage differentiation
GSK-3ß and hair morphogenesis
GSK-3ß and ocular development
GSK-3ß and neuronal polarity
GSK-3ß and brain morphogenesis
GSK-3ß and segmentation
GSK-3ß, glutamate receptors and LTP
Shaggy and transformation

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