Ecdysone receptor

Evolutionary homologs

page 1

Evolution of the nuclear receptor superfamily
Transfer of insect hormone responsiveness to mammals
Ecdysone responses in other insects
Ligand binding of Ecdysone receptors

page 2

Thyroid receptor: a model for Ecdysone receptor in vertebrates

page 3

Thyroid hormone receptor coactivators
Chromatin mediated activation and repression of thyroid hormone responsive genes

page 4

Retinoic acid receptor RAR: a model for Ecdysone receptor in vertebrates - Roles of RAR in development
RAR and cell proliferation

page 5

Retinoic acid receptor RAR: a model for Ecdysone receptor in vertebrates - Transcriptional targets of RAR

page 6

Retinoic acid receptor RAR: a model for Ecdysone receptor in vertebrates - RAR-RXR interaction and binding to DNA
Degradation of RAR

page 7

Chromatin mediated activation and silencing of retinoic acid responsive genes: SMRT and
N-CoR
Chromatin mediated activation and silencing of retinoic acid responsive genes: CBP
Chromatin mediated activation and silencing of retinoic acid responsive genes: PCAF
Chromatin mediated activation and silencing of retinoic acid responsive genes: NSD1
Co-activator complexes: Transcriptional intermediary factor (TIF)and Thyroid hormone receptor-associated protein (TRAP)
Other co-activator complexes

page 8

Nuclear receptor corepressors - interaction with other nuclear receptors and other
transcription factors

Chromatin mediated activation and silencing of retinoic acid responsive genes: Histone
acetylation

Interaction of RAR with Polycomb protein complexes
RAR and long-term potentiation and depression

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