dacapo
Interaction of Dacapo homologs with the cyclin/cdk complex
Interaction of Dacapo homologs with the cyclin/cdk complex: Promotion of the G1/S transition
Interaction of CDK inhibitors with PCNA
Transcriptional regulation of CDK inhibitors
CDK inhibitors, cell cycle arrest and differentiation (part 1/2)
CDK inhibitors, cell cycle arrest and differentiation (part 2/2)
Home page: The Interactive Fly © 1995, 1996 Thomas B. Brody, Ph.D.
The Interactive Fly resides on the
Table of Contents
Subcellular location of CDK inhibitors
Regulation of CDK inhibitors by phosphorylation
Interaction of CDK inhibitors with RB family proteins
CDK inhibitor p27 interacts with RhoA to modulate cell migration
C. elegans CUL-4 prevents rereplication by promoting the nuclear export of CDC-6 via a CDK inhibitor=dependent pathway
Other interactions of CDK inhibitors
CDK inhibitors as targets of the Ras pathway
CDK inhibitors and G2 arrest
A role for Chk1 in blocking transcriptional elongation of p21 RNA
Post-transcriptional regulation of CDK inhibitors
p21 is a negative transcriptional regulator of Wnt4 expression
Degradation of CDK inhibitors
The CRL4Cdt2 ubiquitin ligase targets the degradation of p21Cip1 to control replication licensing
Phenotypic effects of CDK inhibitor mutations
CDK inhibitors and stem cells
The proliferation-quiescence decision is controlled by a bifurcation in CDK2 activity at mitotic exit
CDK inhibitors and senescence
CDK inhibitors and transformation
CDK function in the cytoplasm to regulate cytoskeletal dynamics
dacapo:
Biological Overview
| Regulation
| Developmental Biology
| Effects of Mutation
| References
Society for Developmental Biology's Web server.