eyeless

EVOLUTIONARY HOMOLOGS
Table of Contents

page 1

Pax domain proteins
Phosphorylation and dephosphorylation of Pax-6
Invertebrate Eyeless homologs

page 2

Vertebrate Eyeless homologs
Pax-6 in fish
Pax-6 in Xenopus

page 3

Regulation of avian Pax-6
Transcriptional targeting by avian Pax-6

page 4

Mutations in mammalian Pax-6 homologs: General
Dual requirement for Pax6 in retinal progenitor cells
Mutations in mammalian Pax-6 homologs: Pax-6 role in cortical and sub-cortical development
Identification of positionally distinct astrocyte subtypes whose identities are specified by a homeodomain code
Molecular dissection of Pax6 function: the specific roles of the paired domain and homeodomain in brain development
Mutations in mammalian Pax-6 homologs: Pax-6 role in cerebellar development
Meis2 is a Pax6 co-factor in neurogenesis and dopaminergic periglomerular fate specification

page 5

Mutations in mammalian Pax-6 homologs: Pax-6 role in eye development
Mutations in mammalian Pax-6 homologs: Pax-6 role in neural patterning
Mutations in mammalian Pax-6 homologs: Effects on cell migration
Mutations in mammalian Pax-6 homologs: Pax-6 role in pancreas development
Mutations in mammalian Pax-6 homologs: Pax-6 role in development of other glands

page 6

Regulation of Pax-6 in mammals
Pax-6 transcriptional targets
Pax-6 misexpression produces ectopic eyes
Pax6 is essential for lens fiber cell differentiation

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