Drosophila as
a Model for Human Diseases
- Adams-Oliver syndrome
- Adenoid cystic carcinoma (ACC)
- Adrenoleukodystrophy
- Adult-onset
inherited myopathy
- Aging
and lifespan
- Alcoholism
- alpha-Synucleinopathies
- Alzheimer's
disease - a chronic neurodegenerative disease
- Amyloidosis
- Amyotrophic
Lateral Sclerosis - a motor neuron disease
- Angelman syndrome - a neurogenetic disorder caused by defective ubiquitination
- Ataxia
- Azoospermia/Cryptozoospermia
- Autism spectrum disorder - a genetic disease with modulating environmental and epigenetic factors
- Barth
syndrome - a disease of impaired fatty-acid metabolism
- lipotoxic cardiomyopathy - Obesity- and
type-2-diabetes-related disorders
- Berardinelli-Seip congenital lipodystrophy type 2
- Birt-Hogg-Dubé syndrome
- Cardiac lipotoxicity
- Cachexia or wasting syndrome - organ wasting of adipose, muscle, and gonadal tissue that represents a major obstacle to cancer therapy
- Cardiomyopathy
- a collection of myocardial disorders in which the heart muscle
is structurally and functionally abnormal
- Cerebellar hypoplasia and dysplasia
- CerTra syndrome
- Chediak-Higashi syndrome
- chronic kidney disease
- Ciliopathy
- Charcot-Marie-Tooth
Disease
- Chronic Obstructive Pulmonary Disease
- Cocaine Use Disorder
- Coffin-Lowry syndrome - an X-linked dominant genetic disorder
- Colorectal cancer - cancer of the large intestine
- Congenital disorders of glycosylation
- Cornelia de Lange syndrome - a congenital developmental disorder
- Covid
- Creutzfeldt-Jakob Disease and Prion Disease
- Cystic fibrosis
- Diabetes
- Epilepsy and seizure disorders
- ER stress and unfolded protein response (UPR) associated diseases
- Fanconi Syndrome
- 5q35-microduplication
- Fatty acid hydroxylase-associated neurodegeneration (FAHN)
- Floating-Harbor syndrome
- Fragile X Syndrome - the most common form of intellectual disability
- Freeman Sheldon Syndrome, a skeletal muscle contracture syndromes
- Galactosemia - a genetic disorder of galactose metabolism
- Galloway-Mowat syndrome - a severe, inherited kidney-neurological disease
- Gaucher's disease - a lysosomal storage disease
- Glioma and Glioblastoma
- Heart Disease
- Hereditary neuropathy
- Human papillomavirus E6-induced malignancy
- Huntington's
disease - a neurodegenerative genetic disorder that
affects muscle coordination and leads to mental decline and
behavioral symptoms
- Hypertrophic cardiomyopathy
- Hyperuricemia
- Hypotonia
- Inclusion body myopathy type 3
- Inflammatory Gut Diseases
- Insomnia
- Intellectual
Disability associated with WAC
- Jacobsen syndrome, an 11q terminal deletion developmental disorder
- Kohlschutter-Tonz syndrome
- Laminopathy
- Leigh Syndrome
- Limb-girdle muscular dystrophy D2
- Lysosomal storage disease
- Maple syrup urine disease
- Meier-Gorlin syndrome
- Microcephly
- Mitochondrial disease
- Mucopolysaccharidosis
- Muscular
dystrophy - a group of diseases that cause progressive
weakness and loss of muscle mass
- Myeloproliferative neoplasms
- Myopathy
- Myotonic Dystrophy
- Nephrotic Syndrome
- Neurofibromatosis - an autosomal dominant condition
associated with a high possibility of tumor formation
- Diabetic Neuropathy
- Neurodegeneration
associated with PLA2G6, a phospholipase A2 beta enzyme
that selectively hydrolyses glycerophospholipids
- Neurological disorder with regression, abnormal movements, loss of speech, and seizures (NEDAMSS)
- Neuronal ceroid lipofuscinoses
- Nicotine addiction
- N-Glycanase 1 deficiency - A congenital disorder of deglycosylation
- Niemann-Pick
disease - an early childhood disease exhibiting
progressive neurological degeneration, marked by lipid
accumulation
- Nonalcoholic fatty liver disease
- Noonan syndrome
- Obesity
- Oculopharyngeal muscular dystrophy
- Parkinson's disease - a degenerative disorder of the central nervous
system mainly affecting the motor system
- Peripheral neuropathy
- Peroxisome biogenesis disorders
- Perry syndrome - a progressive brain disease resulting from mutation in the DCTN1 gene which codes for dynactin-1
- Pitt-Hopkins syndrome - a rare, multi-symptomatic neurogenetic disorder
- Polycystic kidney disease
- Polyglutamine
(polyQ) disorders
- Pontocerebellar Hypoplasia
- Primary Ciliary Dyskinesia
- Robinow syndrome
- Renal Fibrosis
- Retinitis
pigmentosa
- Rett
Syndrome - a neurodevelopmental disease caused by
alterations in the expression of Methyl-CpG-binding protein 2
- Rhabdomyosarcoma
- a cancer made up of cells that normally develop into skeletal
muscles
- Ribosomopathies
- Sarcopenia
- Schizophrenia
- Shwachman-Diamond syndrome
- 16p12.1 deletion
- Schizophrenia
- Skin cancer and nucleotide excision repair
- Snyder-Robinson Syndrome
- Spastic paraplegia - a group of inherited neural disorders
characterized by lower limb spasticity
- Spinal muscular atrophy - A neuromuscular disorder resulting from insufficient levels of the survival motor neuron protein
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- Spliceosomopathy
- Spondyloarthritis
- Squamous
cell carcinoma
- Steatosis
- TANGO2 deficiency disease
- Tauopathy
- Traumatic Brain Injury
- Tuberous Sclerosis Complex
- Trichohepatoenteric syndrome
- Triosephosphate isomerase deficiency
- Ultraviolet Damage
- von
Hippel-Lindau (VHL) disease caused by mutation in VHL
protein (pVHL) which regulates Hypoxia inducible factor 1α
- Warburg micro syndrome a hereditary autosomal neuromuscular disorder in humans caused by mutations in Rab18, Rab3GAP1, or Rab3GAP2
- Werner syndrome
- Williams-Beuren Syndrome
- Wilms' tumour
- Wolfram syndrome
- Zika
Additional
Resources
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