POSTER SESSIONS I and II

Session I: 6/8 - 4:00-5:30 P.M. and 9:00-11:00 P.M.

Session II: 6/9 - 4:00-5:30 P.M. and 9:00-11:00 P.M.

All posters are displayed at both sessions.

The authors should be present at respective boards according to the following schedule:

Odd # Boards: Session I (6/8) - 4:00-5:30 pm.

Even # Boards: Session II (6/9) - 4:00-5:30 pm.

B numbers = Board number

Categories

Education

Genomics/Informatics

Medicine and Development

Developmental Timing

Animal Models

Development and Evolution

Plant Development

Gametogenesis and Fertilization

Cell Lineage

Morphogenesis

Organogenesis

Neural Development

Patterning

Body Plan

Metamorphosis

Signaling Pathways

Gene Expression

Cell Biology of Development

Education

B1 Breaking out of the model paradigm: using the comparative approach in undergraduate investigative labs. M.K. Montgomery. Macalester Col.

B2 Investigating genes and development in the biology curriculum. J.T. Warren, Jr., M.A. Campbell, P.E. Barney, L. Eckroat, D.M. McKinstry, J. Patel, K. Wellejus and R.L. Gill, Jr. Pennsylvania State Univ., The Behrend Col.

B3 Undergradutate laboratory exercises in axis specification. J.A. Emerson, St. Louis Univ.

B4 Teaching undergraduates the fundamentals of amphibian mesoderm induction through class discussion and laboratory experimentation. E.R. McCain. Muhlenberg Col.

B5 A method for teaching controls. D.S. Adams. Smith Col.

B6 K-12 science teaching internship program. R. Nuccitelli, T. Rost and G. Lusebrink. UC Davis.

Genomics/Informatics

B7 The gene expression database: a different kind of computer mouse. D.P. Hill, D.A. Begley, J.P. Corradi, J.T. Eppig, J.A. Kadin, R.P. Pazola, J.E. Richardson and M. Ringwald. The Jackson Lab.

B8 Genomic, transcriptional, and mutational analysis of the mouse microphthalmia locus. J.H. Hallsson, J. Favor, G.J. Gunnarsson, N.G. Copeland, N.A. Jenkins and E. Steingrimsson. Univ. of Iceland, NCI-FCRF, and GSF-Inst. of Mammalian Genet., Germany.

Medicine and Development

B9 Aberrant craniofacial development in endothelian-1 knockout mice: emergence of bilateral mandibular protrusions and ectopic maxillo-mandibular fusion. Y. Taya, Y. Soeno, Y. Kurihara, H. Kurihara and T. Aoba. Nippon Dent. Univ. and Univ. of Tokyo, Japan.

Developmental Timing

B10 The C. elegans developmental timing protein LIN-42: a link to circadian rhythms. H.F. Gardner, M. Jeon, J.E. Abrahante and A.E. Rougvie. Univ. of Minnesota.

Animal Models

B11 Pax3/FKHR fusion affects development of the mouse heart. I. Lagutina, J. Sublett, C. McPherson, S. Conway and G. Grosveld. St. Jude Children's Res. Hosp. and Med. Col. of Georgia.

B12 Identification of a genetic interaction between LMX1B and PITX2. C.L. Pressman, J. Martin and R.L. Johnson. M.D. Anderson Cancer Ctr., Univ. of Texas and Texas A&M Univ.

Development and Evolution

B13 Jellyfish striated muscle: a model for the evolutionary origin of myogenic factors? P. M�ller, M. Stierwald, N. Yanze, J. Spring and V. Schmid. Univ. of Basel, Switzerland

B14 The D-quadrant organizer in spiralian development. E. Edsinger-Gonzales, W.J.A.G. Dictus and J.A.M. van den Biggelaar. Smithsonian Marine Sta., Ft. Pierce, FL and Univ. Utrecht, The Netherlands.

B15 Evidence for the conservation of mesodermal determinaltion in molluscs. S.M. Moshel-Lynch, D.R. Lindberg and J.R. Collier. UC Berkeley and Effie Lab., LA.

B16 Mechanisms of sex determination evolution in Caenorhabditis. E. Haag, T.Schedl and J.Kimble. Univ. of Wisconsin and Washington Univ. Sch. of Med.

B17 Using RNAi to study SKN-1 and other homologs governing early nematode development. J. Norman and M.K. Montgomery. Macalester Col.

B18 Mechanisms of segment formation in polychaete annelids. E.C. Seaver and S.D. Hill. Univ. of Hawaii and Michigan State Univ.

B19 Evolution of anteroposterior axis formation in insects: the role of hunchback and nanos in the grasshopper. S. Lall, M.Z. Ludwig and N.H. Patel. Univ. of Chicago.

B20 The evolution of Hox function and arthropod morphological diversity. M.R. Ronshaugen and W. McGinnis. UCSD.

B21 Evolution of arthropod appendage development. M.W. Giorgianni, N.R. Gleich D. DiPietro, M. Averof and N.H. Patel. Univ. of Chicago and Vassilika Vouton, Greece.

B22 Distinct roles for Ubx and Abd-A in the beetle embryonic abdominal appendage development. R.L. Bennett, D.L. Lewis and M.A. Decamillis. Brigham Young Univ. and Univ. of Wisconsin.

B23 The role of Pax group III genes in short-germ segmentation. C.A. Jaramillo, G.K. Davis and N.H. Patel. Univ. of Chicago.

B24 Fringe benefits in arthropods. A.L. Price, M. Hunter, C. Josefowicz and N.H. Patel. Univ. of Chicago and HHMI.

B25 Experimental evolution of development: changes in wing vein phenotypes across compartment boundaries in "hot" and "cold" adapted lab populations of Drosophila melanogaster. D.M. Rand, A. Fry and L. DiChiaro. Brown Univ.

B26 Phylogenetic analysis and expression of amphioxus Wnt genes: a possible ancient function for Wnt1 during gastrulation. M. Schubert, L.Z. Holland, D.K. Jacobs and N.D. Holland. Scripps Inst. of Oceanography and UCLA.

B27 Urochordate cornichon homologue may play a role in metamorphic EGF signalling. B.J. Davidson, W. Moody and B.J. Swalla. Univ. of Washington.

B28 Lamprey Dlx genes and early vertebrate evolution. J.A. Langeland, A.H. Neidert, V. Virupannavar and G.W. Hooker. Kalamazoo Col.

B29 Lens cell death regulates the eyeless phenotype of the cave fish. A.G. Strickler and W.R. Jeffery. Univ. of Maryland.

B30 The lens is a regulator of craniofacial development and evolution in the teleost Astyanax. W.R. Jeffery and Y. Yamamoto. Univ. of Maryland.

B31 Midline signaling in evolutionary regression of vertebrate eye development. Y. Yamamoto, A.G. Strickler, D.W. Stock and W.R. Jeffrey. Univ. of Maryland and Univ. of Colorado, Boulder.

B32 Regressive evolution of melanogenesis in the cavefish astyanax Astyanax. D.W. McCauley and W.R. Jeffery. CalTech and Univ. of Maryland.

B33 The role of the trimolecular complex-MT1-MMP/TIMP2/MMP2 in zebrafish embryogenesis. J. Zhang, S. Bai and M.P. Sarras, Jr. Univ. of Kansas Med. Ctr.

B34 Hoxgene patterning and fish evolution. J.M. McClintock, C. Jozefowicz and V.E. Prince. Univ. of Chicago.

B35 Hoxgene function and regulation during teleost hindbrain and pharyngeal arch development. M. Hunter, J.L. Scemama, E.J. Stellwag and V.E. Prince. Univ. of Chicago and East Carolina Univ.

B36 Toward understanding the evolution of skeletogenesis. B.F. Eames and J.A. Helms. UCSF.

B37 A subtractive hybridization identifies chick-cripto, a novel EGF-CFC ortholog expressed during gastrulation, neurulation, and early cardiogenesis. J-F. Colas and G.C. Schoenwolf. Univ. of Utah Sch. of Med.

Plant Development

B38 Computational development: two examples in plant development--apical/basal cell differentiation in fern gametophytes; and linking concentration pattern to growth in three dimensions. D.M. Holloway and L.G. Harrison. Univ. of British Columbia, Canada.

B39 High throughput analysis of zygote development and putative transformants of the giant unicell acetabularia. L. Krueger and D.F. Mandoli. Univ. of Washington.

B40 Possible roles of one-carbon metabolism in the development of Acetabularia acetabulum. C.L. Richmond and D.F. Mandoli. Univ. of Washington.

B41 Whorls of variable numbers of parts: trying to correlate experiment and theory for Acetabularia and for conifer somatic embryos. L.G. Harrison. Univ. of British Columbia, Canada.

Gametogenesis and Fertilization

B42 Derivatized bead binding to live cells and cells fixed with two fixatives. V.M. Navarro, M.I. Abundis, S.L. Walker, L.L. Ngo, G. Weerasinghe, M. Barajas, O.A. Badali, G. Zem, J.P. Taitz and S.B. Oppenheimer. California State Univ., Northridge.

B43 Dissociation of pH and charge effects on sea urchin fertilization. G.R. Weerasinghe, M. Barajas, E.H. Yamoah, M. Grigorian and S.B. Oppenheimer. California State Univ., Northridge.

B44 Strongylocentrotus drobachiensis oocytes maintain their polarity throughout oogenesis. A.L. Egana, J.A. Boyle and S.G. Ernst. Tufts Univ.

B45 The scattershot mutation disrupts germ cell migration in Drosophila. C.R. Coffman, D. Przychodzin, R.C. Strohm, F.D. Oakley and R.E. Boswell. Iowa State Univ. and Univ. of Colorado.

B46 Using reverse genetics to screen for glh mutants E.A. Coberly, R.A. Montgomery, K.A. Kuznicki, A.W.M. Leung-Chiu and K.L. Bennett. Univ. of Missouri.

B47 Combinatorial RNA interference indicates P granule components GLH-1 and GLH-4 are critical for fertility in Caenorhabditis elegans. K.A. Kuznicki, P.A. Smith, A.W.M. Leung-Chiu and K.L. Bennett. Univ. of Missouri.

B48 Designing integrin-binding peptides by secondary structure analysis. J.W. Norris and R.L. Nuccitelli. UC Davis.

B49 Fertilization and lipid signaling in Xenopus laevis. B.J. Stith, P. Medina, D. Petcoff, W. Holland and K. Savi. Univ. of Colorado, Denver.

B50 Nuclear export and modification of An3p, a DEAD-box RNA helicase in Xenopus laevis. V.M. Ogniewski, L.B. Sutherland and D.L. Weeks. Univ. of Iowa.

Cell Lineage

B51 Erythroid differentiation in vitro is blocked by cyclopamine, an inhibitor of hedgehog signaling. K. Detmer, A.N. Walker, T.M. Jenkins, T.A. Steele and H. Dannawi. Mercer Univ. Sch. of Med., Univ. of Georgia Col. of Agr. and Envrn. Sci. and Med. Ctr. of Central Georgia.

B52 FGF signaling in mouse trophoblast stem cells. T. Kunath, S. Tanaka and J. Rossant. Mount Sinai Hosp., Toronto.

B53 Characterization of the zebrafish nacre/MiT family of bHLH/ZIP proteins. J.A. Lister, J. Close and D.W. Raible. Univ. of Washington.

B54 A role for protein degradation in the asymmetric localization of PIE-1 and other germline factors in C. elegans embryos. K.J. Reese, M.A. Dunn and G. Seydoux. Johns Hopkins Univ. Sch. of Med.

B55 A new gene required for C. elegans tail morphogenesis. T.M. Ratliff and M.A. Herman. Kansas State Univ.

B56 MES-1, a protein required for unequal divisions of the germline in early C. elegans embryos, resembles receptor tyrosine kinases and is localized to the boundary between the germline and gut cells. L.A. Berkowitz and S. Strome. Indiana Univ.

B57 Novel cell-cell interactions determine cleavage plane and eye-forming potential in early Ilyanassa embryos. M.B. Goulding. Univ. of Texas at Austin.

Morphogenesis

B58 Quantitative analyses of zebrafish morphogenesis. R.J. Adams. Univ. of Bath, UK.

B59 Mechanical and geometric determinants of pattern formation during cell rearrangements in embryos. E.M. Munro and G.M. Odell. Univ. of Washington.

B60 Analyses of excision mutants near Imp-L1 of Drosophila. S. Kedia, J.E. Natzle and L.A. Abbott. Univ. of Colorado, Boulder and UC Davis.

B61 Each C. elegans laminin a subunit mediates distinct aspects of morphogenesis. C-C. Huang, P.D. Yurchenco and W.G. Wadsworth. Robert Wood Johnson Med. Sch.

B62 SMA-1 spectrin is required for embryonic morphogenesis in C. elegans. V. Praitis and J. Austin. Univ. of Chicago.

B63 A novel gene, ram-5, is required specifically in structural cell of ray for it proper morphogenesis in Caenorhabditis elegans. R.Y.L. Yu and K.L. Chow. Hong Kong Univ. of Sci. and Technol., PRC

B64 dpy-11 mutations implicate the requirement of protein modification for normal sensory organ morphogenesis in C. elegans. F.C.F. Ko and K.L. Chow. Hong Kong Univ. of Sci. and Technol., PRC

B65 Cell commitment in the zebrafish blastula. D.A. Kane and R. M Warga. Univ. of Rochester.

B66 Genetic control of convergence and extension movements during zebrafish gastrulation. L. Solnica-Krezel, J. Topczewski, D. Sepich, D. Myers, F. Marlow, A. Amores, C. Walker and J. Postlethwait. Vanderbilt Univ. and Univ. of Oregon.

B67 A gradient of BMP activity coordinates the gastrulation movements of convergence and extension. D. Myers, D. Sepich and L. Solnica-Krezel. Vanderbilt Univ.

B68 The localization of focal adhesion kinase (FAK) indicates a role for FAK in cellular intercalation and boundary formation. C.A. Henry, M.S. Cooper and M.B. Hille. Univ. of Washington and Univ. of Oregon.

B69 Somites in knypek;trilobite zebrafish form without mesenchymal internal cells or compaction of the presomitic mesoderm. C.A. Henry, L.A. Hall, L. Solnica-Krezel and M.S. Cooper. Univ. of Washington and Vanderbilt Univ.

B70 Essential role of intact hyaluronan matrix for the elongation of gastrulating mesoderm. G. Lepperdinger and J. Müllegger. Austrian Acad. of Sci., Austria

B71 Neural fold formation and morphogenesis in the chick embryo. A. Lawson, H. Anderson and G. Schoenwolf. Univ. of Utah.

B72 Bone morphogenetic protein-1 (BMP-1) related metalloproteases regulate cartilage formation and BMP growth factor activity in the embryonic chick limb. S.A. Maas, R.D. Dahn, I.C. Scott, J.F. Fallon and D.S. Greenspan. Univ. of Wisconsin Med. Sch.

B73 Hoxa-13 mutant expression downregulates Bapx1 homeodomain gene and leads to hindgut and tail malformations in chicken. P. de Santa Barbara and D.J. Roberts. Massachusetts Gen. Hosp.

B74 Delta-Notch signalling in gut epithelium. M. Skipper, A. Morrison, Y. Jiang and J. Lewis. Imperial Cancer Res. Fund, U.K.

B75 Sonic hedgehog regulates morphogenesis, cell proliferation and differentiation in developing tooth germs. T. Ohmori, M. Iwamoto, H. Okada, M.J. Tabata, K. Kurisu, M. Pacifici and E. Koyama. Osaka Univ. Fac. of Dent., Japan and Univ. of Pennsylvania Sch. of Dent. Med.

B76 Opposing roles of BMP4 and Fgf10 during branching morphogenesis. M. Weaver, N.R. Dunn and B.L.M. Hogan. Vanderbilt Med. Ctr.

B77 Segmentor: an activity that induces boundary formation during somite segmentation. Y. Takahashi and Y. Satou. Nara Inst. of Sci. and Technol., Japan.

Organogenesis

B78 A subtractive screen for Pax6 target genes. K. Coulter and T. Glaser. Univ. of Michigan Med. Ctr.

B79 Molecular mechanism of the chicken Rx/rax underlying neural retina formation. K. Sakagami and K. Yasuda. Natl. Inst. of Sci. Technol., Japan.

B80 Tbx12 function in vertebrate development. B.A. Parr and C.T. Carson. Univ. of Colorado.

B81 Notch regulates Xath5 function during neural plate and retinal stages. M.L. Schneider, D.L. Turner and M.L. Vetter. Univ. of Utah and Univ. of Michigan.

B82 XFz3 promotes ectopic eye formation in Xenopus. J.T. Rasmussen, M.A. Deardorff, M.S. Rao, P.S. Klein and M.L. Vetter. Univ. of Utah and Univ. of Pennsylvania.

B83 Forkhead gene FoxE3 has an important role in vertebrate lens development. I. Brownell and M. Jamrich. Baylor Col. of Med.

B84 Bmp4 is essential for lens induction in the mouse embryo. Y. Furuta. Univ. of Texas, M.D. Anderson Cancer Ctr.

B85 Confocal laser scanning microscopy of Xenopus inner ear organs during larval development. E.E. Serrano and Q.A. Quick. New Mexico State Univ.

B86 Bone morphogenetic proteins regulate morphogenesis of otic membrane, otic capsule chondrogenesis, and their interactions during chicken inner ear development. W. Chang and D. Wu. NIDCD, NIH.

B87 The role of Dlx genes in avian inner ear development. S.T. Brown and A.K. Groves. House Ear Inst., Los Angeles.

B88 Defining genes involved in mammalian inner ear development. M. Ficker N.S. Powles and M.K. Maconochie. MRC, Harwell, U.K.

B89 The developing mouse hearing and balance systems require the orphan nuclear receptor COUP-TFI. F.A. Pereira, C. Shope, W.E. Brownell, S.Y. Tsai and M. Tsai. Baylor Col. of Med.

B90 The consequences of expression of Nkx2.5 truncation mutants on Xenopus heart development. L.B. Sutherland, S.J. Kolker, V.M. Ogniewski, U. Tajchman, J.M. Dagle, C. Greaves and D.L. Weeks. Univ. of Iowa.

B91 Transcriptional regulation of the BMP-induced chick cardiac homeobox gene, Nkx-2.5. K.-H. Lee and A.B. Lassar. Children's Hosp. and Harvard Med. Sch.

B92 Analysis of blood vessel development using transgenic zebrafish. B.M. Weinstein and N.D. Lawson. NICHD, NIH.

B93 Sex-specific mechanisms of vascular development in the mouse gonad. J. Brennan and B. Capel. Duke Univ. Med. Ctr.

B94 Sry and the control of testis organogenesis. B. Capel, J. Karl, C. Tilmann, J. Schmahl, J. Brennan and J. Guille. Duke Univ. Med. Ctr.

B95 Cell proliferation is necessary for the induction of the testis pathway in the XY gonad. J.P. Schmahl and B. Capel. Duke Univ.

B96 Genetics of prepattern formation in the C. elegans gonad. K.R. Siegfried and J. Kimble. HHMI and Univ. of Wisconsin, Madison.

B97 Upregulation of the GDNF receptors in the ectopic ureteric buds induced by GDNF. M.K. Hyt�nen, K. Sainio and H. Sariola. Univ. of Helsinki, Finland.

B98 Kidney cell lines from Hoxa 11-SV40 Tag transgenic mice identify putative targets of the Hoxa 11 gene. M.T. Valerius, L.T. Patterson and S.S. Potter. Children's Hosp. Med. Ctr., Cincinnati.

B99 Leukemia inhibitory factor induces epithelial tubule formation in metanephric mesenchyme through activation of Wnt signaling. A.O. Perantoni, S. Plisov, L.F. Dove, K.G. Higinbotham and K.Yoshino. NCI, NIH.

B100 Patterning the pronephros: a role for notch signaling in kidney organogenesis. K.A. McLaughlin, M.S. Rones and M. Mercola. Harvard Med. Sch.

B101 Mutations affecting the form and function of the zebrafish pronephros. F.C. Serluca and M.C. Fishman. Massachusetts Gen. Hosp.

B102 The role of TNF signaling in the morphogenesis of epithelial appendages: expression and regulation of tabby and downless in mouse teeth. J. Laurikkala, M. Mikkola, T. Mustonen and I. Thesleff. Univ. of Helsinki, Finland

B103 Functional analysis of the A33 antigen. H.E. Abud, C.N. Johnstone, N.C. Tebbutt, S.H. Cody, B. Catimel, E.C. Nice and J.K. Heath. Ludwig Inst. for Cancer Res., Royal Melbourne Hosp., Australia.

B104 Pituitary gland development and hormone production are sensitive to Pitx2 dosage. H. Suh, S.A. Camper and P.J. Gage. Univ. of Michigan.

B105 In vitro development of organogenesis-stage embryos of Sminthopsis macroura (Marsupialia:Dasyuridae). Y.P. Cruz, D. Hickford and L. Selwood. Oberlin Col. and La Trobe Univ., Australia.

B106 Development of the follicle-associated epithelium and bursal secretory dendritic cells in the guinea fowl (Numida meleagris). I. Ol�h, N. Nagy, A. Magyar, Cs. D�vid and M.K. Gumati. Fac. of Med., Semmelweis Univ., Hungary.

B107 SHH signaling is required for feather bud development. V.C. Oropeza, A.A. Ligas and J.A. Cebra-Thomas. Franklin and Marshall Col.

B108 Novel monoclonal antibody identifies avian early myogenic and differentiated smooth muscle cells. N. Nagy, A. Magyar, Cs. D�vid and I. Ol�h. Fac. of Med., Semmelweis Univ., Hungary.

B109 Function of Gdf11 during chick limb development. L. Gamer, K. Cox and V. Rosen. Genet. Inst.

B110 A high-throughput method to identify and characterize novel hematopoietic genes. S.D. Marty and S. Lin. Med. Col. of Georgia.

B111 A novel transcriptional regulator is a candidate for the zebrafish moonshine gene. D.G. Ransom, N. Bahary, B.A. Barut, W.J. Saganic and L.I. Zon. HHMI, Children's Hosp., Boston.

B113 A hedgehog homolog regulates gut formation in leech. D. Kang, D. Li, M. Shankland, W. Gaffield and D. Weisblat. UC Berkeley, Univ. of Texas, Austin and ARS, USDA.

B114 Drosophila salivary gland morphogenesis, a tale of two transcription factors. M.M. Myat and D.J. Andrew. Johns Hopkins Univ. Sch. of Med.

B115 Identification and characterization of failure to fuse, a novel gene required for muscle formation in Drosophila. V. Corbin, J. Rusconi, S. Gordon, P. Bajaj and J. Aracena. Univ. of Kansas, Univ. of Kansas Med. Sch. and Mississippi Univ. for Women.

B116 The homeobox gene Pdx1 is sufficient for endoderm cells to initiate pancreas formation. A. Grapin-Botton and D.A. Melton. HHMI and Harvard Univ.

B117 Pancreatic islet-like cells derived from mouse ES cells. B.W. Kahan, L.M. Jacobson, D.A. Hullett and J.S. Odorico. Univ. of Wisconsin Med. Sch.

Neural Development

B118 C. elegans UNC-4 targets ACR-5 and DEL-1: are they determinants of synaptic choice? S.E. Von Stetina and D.M. Miller III. Vanderbilt Univ.

B119 Ecdysteroid coordinates optic lobe neurogenesis via a nitric oxide signaling pathway. D.T. Champlin and J.W. Truman. Univ. of Washington.

B120 nerfin-1, a new Pan-neural Zn-finger gene is required for proper nervous system development in Drosophila. C. Stivers, A. Kuzin, T. Brody and W.F. Odenwald. NINDS, NIH.

B121 Talin: a conserved cytoskeletal linker protein expressed in a subset of CNS neurons. T. Brody, C. Stivers and W.F. Odenwald. NINDS, NIH.

B122 Cell fate determination mechanisms in the insect central nervous system. B.C. Lear, J.B. Skeath and N.H. Patel. Univ. of Chicago and Washington Univ.

B123 Migration of cranial motor neurons is eliminated in the zebrafish gastrulation mutant trilobite. A. Chandrasekhar and S. Bingham. Univ. of Missouri.

B124 Development of epibranchial placodes in Ambystoma mexicanum. J.B. Gross and L.A. Barlow. Univ. of Denver and Univ. of Colorado Hlth. Sci. Ctr.

B125 Establishing neuronal identity in vertebrate neurogenic placodes. C.V.H. Baker and M. Bronner-Fraser. Caltech.

B126 The sensory-deprived^w15 mutation is required for development of the dorsal root ganglia in zebrafish. J.M. Ungos, T. Linbo and D.W. Raible. Univ. of Washington.

B127 Curly fry, a neural crest deficient mutant. A.E. Davidson, J.C. Shaffer, C. Saunders, D. Mohn, P.D. Henion, P.B. Hackett and S.C. Ekker. Univ. of Minnesota and Ohio State Univ.

B128 CD44-ERBB receptor interactions facilitate neural crest cell differentiation. L. Sherman, M. Bevers and H. Horn. Univ. of Cincinnati.

B129 Concurrent expression of recombination activating genes 1 and 2 in the zebrafish olfactory system. J.R. Jessen, T.N. Jessen and S. Lin. Med. Col. of Georgia.

B130 The spatiotemporal expression order limits the potential of Brn-3 factors to promote retinal ganglion cell differentiation. W. Liu, S.L. Khare, X. Liang, X. Liu, M.A. Peters, C.L. Cepko and M. Xiang. UMDNJ-Grad. Sch. of Biomed. Sci.

B131 The role of histone deacetylase in the regulation of notch signaling in the mammalian cochlea. P.J. Lanford and M.W. Kelley. NIDCD, NIH.

B132 Transcriptional regulators of MATH1. P.J. Ebert and J.E. Johnson. Univ. of Texas Southwestern Med. Ctr.

B133 Neuroligin 3 is expressed in a wide range of glia during development. M.M. Gilbert, J. Smith, A. Roskams and V.J. Auld. Univ. of British Columbia, Canada.

B134 Heparan sulphate plays a role in closure of the neural tube in the mouse embryo. G.W. Yip, P. Ferretti and A.J. Copp. University Col. London, U.K. and Univ. of Singapore, Singapore

B135 Metabolism of choline in neurulating mouse embryos. M.C. Fisher, K.M. Denno, M.H. Mar, S.H. Zeisel and T.W. Sadler. Univ. of North Carolina-Chapel Hill.

B136 Sonic hedgehog regulation of midbrain pattern formation. S. Agarwala and C.W. Ragsdale. Univ. of Chicago.

B137 Ectopic BMPs disrupts chick telencephalic development through the repression of Shh and FGF8 gene expression and the regulation of apoptosis. Y. Ohkubo and J.L.R. Rubenstein. UCSF.

B138 Patterning of midbrain and hindbrain by isthmic FGF8. I. Mason, D. Chambers, C. Irving, H. Shamim and J. Walshe. King's Col. London, U.K.

B139 Analysis of Fgf8 function in the development of the mouse midbrain and anterior hindbrain. C.L. Chi, S. Martinez, W. Wurst and G.R. Martin. Sch. of Med., UCSF, Fac. of Med., Univ. Murcia, Spain and GSF-Res. Ctr., Inst. for Mammalian Genet., Germany.

B140 zpl4, a zebrafish gene expressed in an fgf8-dependent manner, may play a role in patterning the rostral hindbrain. M.E. Lane, A.P. Runko and C.G. Sagerstrom. Univ. of Massachusetts Med. Ctr.

B141 A novel Pbx family member expressed during early zebrafish embryogenesis forms trimeric complexes with Meis3 and Hoxb1b. N. Vlachakis, D.R. Ellstrom and C.G. Sagerstrom. Univ. of Massachusetts Med. Sch.

B142 Role of muscle segment homeobox-B in zebrafish neural development. B.B. Riley, B.T. Phillips and A. Fritz. Texas A&M Univ. and Emory Univ.

B144 Cloning and characterization of GABA transporter genes in Xenopus L. August, K.Hoke, D.Solomon, N.Madden and M. Saha. Col. of William and Mary.

B145 Xrx1 in neural plate differentiation. M. Andreazzoli. NICHD, NIH and Univ. of Pisa, Italy.

B146 XHMG4, a novel Xenopus member of the HMG1/2 family, is expressed in the developing nervous system. C. Prothmann, C. Vorbach and R.A.W. Rupp. Max-Planck Gesellschaft, T�bingen.

B147 Identification of XSIP1, a zinc finger/homeodomain transcription factor expressed during early neural development. L. van Grunsven, C. Papin, K. Opdecamp, B. Avalosse, D. Huylenbroeck, J. Smith and E. Bellefroid. Flanders Interuniv. Inst. for Biotechnol., Belgium and NIMR,U.K.

B148 The maternal gene product, tumorhead, induces cell proliferation and regulates neural differentiation in Xenopus embryos. C. Fen Wu and L.D. Etkin. Univ. of Texas, M.D. Anderson Cancer Ctr.

B150 XEbf3 functions as an effector of XNeuroD during neurogenesis. O. Pozzoli, A. Bosetti, L. Croci, G.G. Consalez and M.L. Vetter. HSR Sci. Inst., Milan, Italy and Univ. of Utah.

Patterning

B151 A role for the Exd/PBC homolog CEH-20 in C. elegans embryogenesis? Q.F. Boese and W.B. Wood. Univ. of Colorado.

B152 C. elegans embryonic axial patterning requires two recently discovered posterior-group Hox genes and a homothorax homolog. K. Van Auken, D.C. Weaver, B. Robertson, U. Elling, L.G. Edgar and W.B. Wood. Univ. of Colorado, Boulder.

B153 MEX-3 interacting proteins required to regulate pal-1 translation. N.N. Huang, A.J. Walhout, M. Vidal and C.P. Hunter. Harvard Univ. and Dana Farber Cancer Inst.

B154 Head regeneration of an aquatic oligochaete, Lumbriculus variegatus, is precisely regulated and correlated to engrailed gene expression. K. Crawford, D.R. Backof, D.R. Angelini, H. Hatcher and R.L. Beach. St. Mary's Col. of Maryland and Hollins Univ.

B155 Sea urchin fringe: identification and preliminary functional analysis. R.E. Peterson and D.R. McClay. Duke Univ.

B156 Patterning the Drosophila eggshell: a role for 18-wheeler. S.K. Syed and E.D. Eldon. Univ. of Notre Dame.

B157 dSmurf1, a ubiquitin-protein ligase that modulates BMP signaling in Drosophila. S.D. Podos and E.L. Ferguson. Univ. Chicago.

B158 Drosophila sulfatase1 regulates developmental signaling during development. D.M. Standiford, W. Tao Sun and C.P. Emerson, Jr. Univ. of Pennsylvania.

B159 Localized protein degradation regulates Paired protein expression in Drosophila development. P. Vivekanand, L. Raj, M. Fernandes, S.D. Hanes, L.F. Appel and M. Weir. Wesleyan Univ. and SUNY Albany.

B160 arrow encodes an LDL receptor related protein essential for reception of the wingless signal in Drosophila. M. Wehrli, A. Rives and S. DiNardo. Univ. of Pennsylvania Med. Ctr.

B161 The effect of the proteoglycan Syndecan on the development of Drosophila. T.R. Heslip and J.L. Marsh. Fac. of Med., Univ. of Calgary and UC Irvine.

B162 Identification and analysis of two new genes involved in the control of cell polarity during C. elegans development. X. Zhao and M.A. Herman. Kansas State Univ.

B163 Determining the function of the planar cell polarity gene strabismus in vertebrate development. M. Park and R.T. Moon. Univ. of Washington Sch. of Med. and Ctr. for Develop. Biol.

B164 Patterning the vertebrate gastrointestinal tract. D. Smith, R.C. Grasty, N.M. Nascone-Yoder and C.J. Tabin. Harvard Med. Sch. and Eckerd Col.

B165 mRNA localization patterns in zebrafish oocytes. C.E. Howley and R.K. Ho. Princeton Univ.

B166 A mutagenesis screen to identify maternal factors specifically required in early development of the zebrafish. D.S. Wagner, K.A. Mintzer, R. Dosch and M.C. Mullins. Univ. of Pennsylvania.

B167 Roles of chameleon in midline signaling. A. Kawakami, W.S. Talbot and A.F. Schier. NYU Sch. of Med., Stanford Univ. Sch. of Med. and Natl. Inst. of Genet., Mishima, Japan.

B168 Delta-Notch mediated regulation of midline cell fate. A.J. Latimer and B. Appel. Vanderbilt Univ.

B169 Isolation and characterisation of two Mab21 gene family members in Danio rerio. Y.M. Wong and K.L.Chow. Hong Kong Univ. of Sci. and Technol., PRC

B170 The role of one-eyed pinhead and Nodal signaling in left-right axis determination. R.D. Burdine, K. Gritsman, J. Corrales, W.S. Talbot and A.F. Schier. NYU Sch. of Med. and Stanford Univ. Sch. of Med.

B171 Reticulospinal-less: a zebrafish mutant defective in hindbrain, head periphery, and mesodermal patterning. L. Maves and C.B. Kimmel. Univ. of Oregon.

B172 Genetic analysis reveals a role for FGF signaling in the production of posterior mesoderm in zebrafish. B.W. Draper, D.W. Stock and C.B. Kimmel. Univ. of Oregon and Univ. of Colorado.

B173 The role of Hedgehog signaling in patterning the zebrafish sclerotome. S.H. Devoto, M.J.F. Barresi, J. D'Angelo and H.L. Stickney. Wesleyan Univ.

B174 Hedgehog signal transduction is required for early, but not late, slow muscle development in zebrafish. M.J. Barresi, H.L. Stickney and S.H. Devoto. Wesleyan Univ.

B175 Is Chordin a long-range or short-range acting factor? Roles for BMP1-related metalloproteases in regulating chordin action during early Xenopus embryogenesis. I.L. Blitz, O. Shimmi, K. Wuennenberg-Stapleton, M.B. O'Connor and K.W.Y. Cho. UC Irvine and Univ. of Minnesota.

B176 BMP binding modules in Chordin: new clues on the molecular mechanism that regulates dorsoventral patterning. J.A. Larrain, M. Oelgeschlager, D. Geissert and E.M. De Robertis. UCLA.

B177 Investigating the molecular interactions of chordin and BMP-1/TLD-like proteases in regulating TGF?-like growth factor activities. W.N. Pappano, I.C. Scott, I.L. Blitz, K.W.Y. Cho and D.S. Greenspan. Univ. of Wisconsin Med. Sch. and UC Irvine.

B178 Voltage sensitive calcium channels participate in the dorsalization of the mesoderm in Xenopus laevis. V.A. Palma, R. Mayor and M. Kukuljan. Univ. of Chile.

B179 Regulation of anterior/posterior development by Spemann's organizer. M.C. Lane, T. Smith and M.D. Sheets. Univ. of Wisconsin.

B180 Pitx1: the next regeneration. S. Perry, W.Y. Chang and M.J. Crawford. Univ. of Windsor.

B181 Involvement of xPitx genes in cement gland formation and head development F. Khosrowshahian, W.Y. Chang, M.J. Crawford. Univ. of Windsor, Canada.

B182 Anterior ectodermal patterning in Xenopus laevis: the role of the homeobox genes Pitx1 and Pitx2. A. Schweickert, H. Steinbeisser and M. Blum. Forschungszentrum Karlsruhe and Max-Planck-Institut, Germany.

B183 Embryonic expression of Xenopus Mab21l2 is required for neural tube closure, eye development and posterior structure formation. G.T.C. Lau, O.G.W. Wong, P.M.Y. Chan, K.H. Kok, R.L.Y. Wong, K.T. Chin, M.C.M. Lin, H.F. Kung and K.L. Chow. Hong Kong Univ. of Sci. and Technol. and Hong Kong Univ., PRC

B184 Mesendoderm induction by Hfh2. D.S. Kessler, M.J. Engleka, E. Brown, V. Cluzet, E. Craig, R. Foreman and P.A. Labosky. Univ. of Pennsylvania.

B185 Maternal VegT initiates Xenopus endoderm formation. J. Xanthos, C. Wylie and J. Heasman. Univ. of Minnesota Sch. of Med.

B187 Bapx1, Bmp4, and Nkx2.5 are involved in patterning regions of the chick gut. C.M. Nielsen, L.C. Murtaugh and D.J. Roberts. Massachusetts Gen. Hosp. and Harvard Med. Sch.

B188 Patterning of the chick pronephric kidney. R.G. James and T.M. Schultheiss. Beth Israel Hosp., Harvard Med. Sch.

B189 Hedgehog signaling during mouse ES cell embryoid body development. P. Maye, L. Kasameyer, S. Becker, N. Byrd and L. Grabel. Wesleyan Univ.

B190 Genetic control of the nodal locus. D.P. Norris and E.J. Robertson. Harvard Univ.

B191 Establishment of region specific knockout for gastrulation stage mouse embryo. S. Miura and Y. Mishina. NIEHS, NIH.

B192 The role of mouse Mab21 genes in embryonic turning, neural tube, and notochord differentiation. R.L.Y. Wong and K.L. Chow. Hong Kong Univ. of Sci. and Technol., PRC

B193 A fate MAP of rhombomere 4 and its derived neural crest in normal and hoxb-1 mutant mice. S. O'Gorman, E.A. Barcarse, T. Trieu and C.-W. Liu. The Salk Inst. for Biol. Studies.

B195 A role for Gbx2 in repression of Otx2 and positioning the mid/hindbrain organizer. S. Millet, K. Campbell,D.J. Epstein, K. Losos, E. Harris and A.L. Joyner. HHMI, Skirball Inst., New York.

B196 The antagonistic relationship between open brain and Sonic Hedgehog in patterning the mouse neural tube. J.T. Eggenschwiler and K.V. Anderson. Sloan Kettering Inst.

B197 Pattern formation in the mammalian optic vesicle. M.T. Nguyen and H. Arnheiter. NINDS, NIH.

B198 Mouse endoderm development. J.M. Wells and D. Melton. Harvard Univ.

B199 Distal most limb structures develop despite absence of Shh signaling in mouse. P. Kraus, D. Fraidenraich, C. Basilico and C.A. Loomis. NYU Sch. of Med.

B200 Left-right patterning of the developing cardiovascular system. E.N. Meyers. Duke Univ.

B201 The role of pumilio in patterning and germ cell development in the mouse embryo. D.M. Boucher, Y. Ruan, M.L. Flannery, Y-N. Jan and R.A. Pedersen. UCSF.

Body Plan

B202 Synergistic interactions between T-box transcription factors, FGF8 and one-eyed pinhead in posterior mesoderm formation. K.J.P. Griffin and D. Kimelman. Univ. of Washington.

B203 Functional analysis of a new bHLH family, hesr-1, -2, and -3: potential regulators of vertebrate. H. Kokubo, Y. Lun, L. Gan and R.L. Johnson. Univ. of Texas M.D. Anderson Cancer Ctr.

B204 Orphan receptor germ cell nuclear factor is required for somitogenesis and correct anterior-posterior development of mouse embryos. A.J. Cooney, F.A. Pereira and A.C-K. Chung. Baylor Col. of Med.

B205 The mouse Vg1-related gene, mGDF3 affects left-right axis formation in Xenopus. M. Li, J. Yost, J. McGrath and M. Brueckner. Yale Univ. and Univ. of Utah.

B206 The EGF-CFC gene Cryptic is essential for left-right axis formation in mouse development. Y-T. Yan, J. Ding, S.M. Price and M.M. Shen. Robert Wood Johnson Med. Sch.-UMDNJ.

B207 The proprotein convertases SPC1/Furin and SPC4/PACE4 establish the balance between mutually antagonistic TGFbeta signaling pathways required for left-right axis formation. D.B. Constam and E.J. Robertson. Harvard Univ. and Swiss Inst. for Exptl. Cancer Res.

B208 Vertebrate left-right asymmetry: the rabbit embryo as a new mammalian model system. A. Fischer. Forschungszentrum Karlsruhe and Univ. of Bonn, Germany.

Metamorphosis

B209 Regulation of metamorphosis in ascidians. C.D. Bishop, W.R. Bates and B.P. Brandhorst. Simon Fraser Univ., Canada, Bamfield Marine Sta., and Okanagan Univ. Col., Canada.

B210 Role of Nkx-2.3 homeobox gene in skin differentiation of Xenopus laveis. C.M Ma and L. Miller. University of Illinois-Chicago.

Signaling Pathways

B211 The Hedgehog signaling pathway in early mouse development. X. Zhang, M. Ramalho-Santos and A.P. McMahon. Harvard Univ.

B212 Structure/function studies of the Hedgehog receptor J.E. Hooper and R.A. Young. Univ. of Colorado Hlth. Sci. Ctr.

B213 Genetic separation of the Hh signaling pathway into three discrete branches Q.T. Wang and R.A. Holmgren. Northwestern Univ.

B214 Characterization of habanero: a gene that is involved in dorsal-ventral patterning in Drosophila. A.E. Scherer and J.B. Duffy. Indiana Univ.

B215 Activation of Toll signaling in Drosophila involves Pelle autophosphorylation. B. Shen and J.L. Manley. Columbia Univ.

B216 A molecular basis for competence and for the specificity of ras signaling in mesoderm development. M.S. Halfon, A. Carmena, M. Baylies and A.M. Michelson. HHMI and Brigham and Women's Hosp. and Mem. Sloan-Kettering Cancer Inst.

B217 Ras and Notch signaling pathways interact to generate specific cell fates during Drosophila mesoderm differentiation. A. Carmena, E. Buff, F. Jim�nez, M. Baylies and A. Michelson. Mem. Sloan-Kettering Cancer Ctr., Brigham & Women's Hosp., and Univ. Miguel Hern�ndez, Spain.

B218 Analysis of the function of the Scw prodomain. M.Q. Nguyen and K. Arora. UC Irvine.

B219 The IMP-E1 gene is independently regulated by ecdysteroids and the hemipterous/JNK pathway during Drosophila embryogenesis. J.E. Natzle, K.E. Clark and G.D. Vesenka. UC Davis.

B220 Conventional and unconventional roles for POP-1/Tcf function in C. elegans. M.A. Herman. Kansas State Univ.

B221 Eph signaling is required for gastrulation and prechordal plate movement. J. Chan, J.D. Mably, J.N. Chen, N.B. Goldstein, M. Thomas, J. Cleary, M.C. Fishman and T.M. Roberts. Dana-Farber Cancer Inst. and Massachusetts Gen. Hosp.

B222 The regulation of organizer function by the FGF signaling pathway. T.M. Smith and M.D. Sheets. Univ. of Wisconsin-Madison.

B223 Maternal Xaxin is essential for normal dorsal axis formation in Xenopus. M. Kofron, P. Klein and J. Heasman. Univ. of Minnesota and Univ. of Pennsylvania Sch. of Med.

B224 Direct physical interaction among Lef/Tcf, B-catenin and Smad4 transcription factors in formation of Spemann's organizer. M.K. Hashimoto, M. Nishita, S. Ogata, M.N. Laurent, N. Ueno, H. Shibuya and K.W.Y. Cho. UC Irvine and Natl. Inst. for Basic Biol., Japan.

B225 A novel cleavage site within the pro domain of the BMP-4 precursor regulates the signaling range and biological activity of mature BMP-4. Y. Cui, V. Anthony and J. Christian. Oregon Hlth. Sci. Univ.

B226 Overlapping and distinct functions of GDF6 and BMPs. C. Chang and A. Hemmati-Brivanlou. Rockefeller Univ.

B227 Collagen XVIII is essential for early kidney tubulogenesis: evidence from Wnt signalling pathway induced by lithium chloride. Y. Lin, S. Zhang, R. Heljasvaara, M. Rehn, R. Pihlajaniemi and S. Vainio. Univ. of Oulu, Finland.

B228 Multiple roles for activated LEF/TCF/beta-catenin transcription complexes during hair organogenesis. R. Dasgupta and E. Fuchs. HHMI and Univ. of Chicago.

B229 Notch signaling is required for ephrinB2 expression and proper vascular development. N.D. Lawson, C.-H. Kim, A. Chitnis and B.M. Weinstein. NICHD, NIH.

B230 Homocysteine-induced disruption of vascular development. K.S. Eastep and T.H. Rosenquist. Univ. of Nebraska Med. Ctr.

B231 PI3 kinase activity affects formation and expansion of the amniotic membrane in avian embryos. T.E. Macdonald and B. Holton. Univ. of Wisconsin, Oshkosh.

B232 FGF and TGFbeta regulate different aspects of skeletal muscle development in vivo. H. Flanagan-Steet and B.B. Olwin. Univ. of Colorado, Boulder.

B233 Known and novel phosphatases expressed in the developing chick limb. D.D.W. Cornelison and B.B. Olwin. Univ. of Colorado, Boulder.

B234 Sonic Hedgehog-mediated regulation of myogenesis. Y. Bren and B.B. Olwin. Univ. of Colorado, Boulder.

B235 Profile of protein kinase C isozymes in preimplantation mouse development. H. Dehghani and A.C. Hahnel. Univ. of Guelph, Canada.

B236 Germ cell nuclear factor is critical for the left-right asymmetry in mouse embryos. A.C.-K. Chung, F.A. Pereira and A.J. Cooney. Baylor Col. of Med.

B237 Transcriptional regulation of mouse trophoblast development. C. Mao, D. Strumpf, B. Ciruna, L. Schwartz and J. Rossant. Samuel Lunenfeld Res. Inst., Mount Sinai Hosp., Canada

B238 Smad1 is required for chorioallantoic placenta formation during murine development. J. Ryan, L. Garrett, C. Deng, X-F. Wang, A. Wynshaw-Boris, A. Roberts and R. Lechleider. Uniformed Serv. Univ. of the Hlth. Sci., NCHGR, NIDDK, NIH, Duke Univ. and NCI, NIH.

B239 Dissection of the roles of wingless pathway members in hair morphogenesis and in hair tumor development. U. Gat, E. Chan, L. Degenstein and E. Fuchs. HHMI, Univ. of Chicago.

B240 Studies of the role of mNotch1 phosphorylation in signal transduction. D.R. Foltz and J.S. Nye. Northwestern Univ. Med. Sch.

B241 Cell density-dependent signaling in malignant cells. M.V. Agrez. Univ. of Newcastle, Australia.

B242 SIP2, an RNA-binding Smad-interacting protein, may identify a new mechanism of Smad function in TGF-b signal transduction. C. Collart, J.E. Remacle, L. Van Grunsven, K. Verschueren and D. Huylebroeck. Flanders Interuniv. Inst. for Biotechnol. and Univ. of Leuven, Belgium.

Gene Expression

B243 Enabling developmental genomics: representative mRNA amplification. L.R. Baugh, A.A. Hill, E.L. Brown and C.P. Hunter. Harvard Univ. and Genetics Inst.

B244 Microarray analysis reveals genes potentially functionally involved in specific vascular SMC growth phenotype. M.C.M. Weiser-Evans, P. Mourani, B.E. Quinn and K.R. Stenmark. Univ. of Colorado Hlth. Sci. Ctr.

B246 PITX2 expression and activity in a tooth epithelial cell line. T.A. Hjalt, L.B. Sutherland, E.V. Semina, J.C. Murray, M.L. Snead and B.A. Amendt. Univ. of Iowa, USC Sch. of Dent. and Univ. of Tulsa.

B247 Up-regulation of a fatty acid transporter in adipocyte differentiation and alcoholic fatty liver. M.W. Bradbury, X. Fan and P.D. Berk. Mt. Sinai Sch. of Med.

B248 Retinoic acid altered expression of BMP2. K.L. Abrams and M.B. Rogers. Univ. of South Florida.

B249 Isolation of early cardiomyocyte cell lines from Nkx2.5/simian virus 40 large tumor antigen transgenic mice E. Brunskill, D. Witte, K. Yutzey and S. Potter. Childrens' Hosp. Med. Ctr., Cincinnati.

B250 Immunocytochemical localization of Hex in cultured cells and mouse embryo. B. Ghosh, G.R. Ganea, H.C. Jacobs and C.W. Bogue. Yale Univ. Sch. of Med.

B251 Regulation of AP-2? in the developing frontal nasal mass. A.L. Donner and T. Williams. Yale Univ.

B252 Analysis of fibroblast growth factors in ear development. T.J. Wright and S.L. Mansour. Univ. of Utah.

B253 Transcriptional regulation of two putative corneal enzyme-crystallins in the rabbit: ALDH1 and TKT. R.B. Hough and J. Piatigorsky. NEI, NIH.

B254 A differential screen to identify genes during gastrulation in mouse embryos. C.C. Poncet and R.L. Johnson. Univ. of Texas M.D. Anderson Cancer Ctr.

B255 Expression patterns of Wnts and Sfrp family members suggest interaction during neural crest specification. M. Baranski, H. Magan, K. Terry, E. Berduogo, J. Sandler, L.M. Galli and L.W. Burrus. San Francisco State Univ.

B256 Mechanisms of gene regulation by the Msx1 homeoprotein in vitro and in vivo. A.J. Bendall, G. Hu, J. Ding, M.M. Shen and C. Abate-Shen. Ctr. for Adv. Biotechnol. and Med. and UMDNJ-Robert Wood Johnson Med. Sch.

B257 A novel RNA containing a potential promoter domain corrects the cardiac mutation in Mexican axolotls, Ambystoma mexicanum. C. Zhang, D. Foster, X. Huang, S. Lemanski, F. Meng, D. Dube and L. Lemanski. Texas A&M Hlth. Sci. Ctr. and SUNY, Syracuse.

B258 Xenopus MRF4 gene regulation. S.S. Dirscherl and T.J. Hinterberger. Univ. of Alaska Anchorage.

B259 Xenopus six1 gene is expressed broadly throughout all neurogenic cranial placodes and is maintained in the differentiating lateral lines. P.D. Pandur, S.A. Brugman and S.A. Moody. George Washington Univ.

B260 A novel family of retrotransposons in Xenopus with a developmentally regulated expression. S.Shim and J.K. Han. Pohang Univ. of Sci. and Technol., South Korea.

B261 The regulation of Rpx/Hesx1 gene in early embryonic development. S-J. Chou, H. El-Hodiri, E. Hermesz and K. Mahon. Baylor Col. of Med.

B262beta-catenin regulates the early expression of the Xenopus anti-neural factor DIx3. M.J. Beanan, J.A. Feledy and T.D. Sargent. NICHD, NIH.

B263 The role of HIF genes and hypoxia in early Xenopus development. E.J. Gruber, N. Sadjadi and M.S. Saha. Col. of William and Mary.

B264 Transgenic analysis of the zebrafish chordin promoter. V. Miller-Bertoglio and M.E. Halpern. Carnegie Inst. of Washington.

B265 Cloning and expression of zebrafish homolog of human Ring 3/Drosophila fsh/rat mud-6 gene. T.D. Ebert, J. Guinto and A.J. DiBenedetto. Villanova Univ.

B266 Distribution of polycomb protein during embryogenesis in zebrafish. R.I. Achong, D. Greene, G. Packert, Y-W.P. Lin and T. Petrino. Barry Univ., FL.

B267 Insertional mutagenesis and gene tagging with the sleeping beauty transposon system in zebrafish. P.B. Hackett, K. Clark, A. Davidson, A. Dupay, D. Largaspaeda and S.C. Ekker. Univ. of Minnesota.

B268 Partner of Paired is part of a protein degradation complex. T.K. Das, L. Raj and M. Weir. Wesleyan Univ.

B269 A protein with many faces: the functions of Cap 'n' collar B in anterior-posterior diversification of the Drosophila head. A. Veraksa, N. McGinnis, X. Li, J. Mohler and W. McGinnis. UCSD and Barnard Col., New York.

B270 Aryl hydrocarbon receptor signaling in C. elegans. J.A. Powell-Coffman, H. Jiang and R. Guo. Iowa State Univ.

B271 Transcriptional control of the C. elegans hox gene ceh-13. A. Streit, R. Kohler, T. Marty, M. Belfiore, C. Stoyanov, M. Affolter, R. Schnabel and F. M�ller. Univ. of Fribourg, Univ. of Basel and TU Braunschweig, Switzerland

B272 mab-21 expression is required for sensory ray 6 differentiation and is dynamically regulated during postembryonic C. elegans development. S. Ho and K. Chow. Hong Kong Univ. of Sci. and Technol., PRC

B273 Characterization of the Cnidarian daughterless/E12 hololog Cnda. A. Grens. Indiana Univ.

Cell Biology of Development

B274 Analysis and characterization of two conserved domains in the Drosophila split ends gene. K.A. Mace and W. McGinnis. UCSD.

B275 In vivo functional cooperation of insulin-like growth factor I and leukemia inhibitory factor studied in mutant mice. F. de Pablo, C. Ferandez-Moreno, C. Vicario-Abejon, P.H. Patterson and J.G. Pichel. Ctr. of Investigaciones Biologicas, CSIC, Spain and Caltech.

B276 A hairy homolog in leech. M.H. Song and D. Weisblat. UC Berkeley.

B277 A nanos-homolog in Helobdella (leech) germline precursors. D.A. Weisblat, M. Pilon and D. Kang. UC Berkeley.

B278 Intracellular motility genes and asymmetric cell division in the nematode C. elegans. R.J. Cheeks and B. Goldstein. Univ. of North Carolina.

B279 Chromosome segregation during embryonic mitosis requires importin alpha-2. K.G. Geles and S.A. Adam. Northwestern Univ. Med. Sch.

B280 Kinesins in the early Xenopus laevis embryo. A. Moran, C. de la Cova, J. Heasman and C.C. Wylie. Univ. of Minnesota Sch. of Med.

B281 Cell polarity and microtubules: the PAR-1 connection? R. Benton, J. Shulman and D. St. Johnston. Univ. of Cambridge, U.K.

B282 Expression of PAR-6 in Xenopus laevis. S.C. Choi, J.Kim and J.K. Han. Pohang Univ. of Sci. and Technol., South Korea.

B283 Membrane dynamics during cytokinesis in Xenopus embryos. M.V. Danilchik, E.E. Brown and K. Ray. Oregon Hlth. Sci. Univ.

B284 Role of p53 family members in the early development of Xenopus laevi. P. Lu, J. Wallingford and P. Vize. Univ. of Texas, Austin.

B285 Modulation of N1 protein levels by intracellular antibody transfection inhibits the initial heartbeating in Mexican axolotl. F. Meng, X. Huang, R. Zadjel, S. Lemanski, C. Zhang, D. Foster, D. Dube and L. Lemanski. Texas A&M Univ. Hlth. Sci. Ctr. and SUNY Hlth. Sci. Ctr.

B286 The regulation of apoptosis in the endocardial cushions of the developing chick heart. W.M. Keyes, D.W. Li and E.J. Sanders. Univ. of Alberta, Canada.

B287 Transcription factor ERG variants and functional diversification of chondrocytes during limb skeletogenesis. M. Iwamoto, Y. Higuchi, E. Koyama, M. Enomoto-Iwamoto, K. Kurisu, H. Yeh, W.R. Abrams, J. Rosenbloom and M. Pacifici. Osaka Univ. Fac. of Dent., Japan and Univ. of Pennsylvania Sch. of Dent. Med.

B288 Analysis of the molecular clock implicated in somitogenesis. K.J. Dale, J. Dubrulle, C. Jouve, M. Maroto, M. McGrew and O. Pourquie. CNRS, Campus de Luminy, France

B289 Identification of new satellite cell markers and their role in signaling in satellite cells on intact myofibers. B.B. Olwin, H. Stenley, D. Cornelison, M. Filla and A.C. Rapraeger. Univ. of Colorado and Univ. of Wisconsin-Madison.

B290 Characterization of focal adhesion kinase in the sea urchin embryo. M. Guadalupe Garc�a and M.B. Hille. Univ. of Washington.

B291 Disruption of cell contacts alters the development of amphibian taste buds. M.A. Parker and L.A. Barlow. Univ. of Denver and Univ. of Colorado Hlth. Sci. Ctr.

B292 Isolation, characterization, and functional studies of rac, rho, and cdc42 in Xenopus development. J.M. Lucas, R. Ren and M.D. Hens. Univ. of North Carolina Greensboro.

B293 Developmental expression of Tiam-1 in preimplantation mouse embryo. P.M. Martin and A.E. Sutherland. Univ. of Virginia.

B294 The Hand1 bHLH factor regulates trophoblast differentiation via multiple mechanisms. I.C. Scott, L. Anson-Cartwright, P. Riley and J.C. Cross. Mount Sinai Hosp. and Univ. of Toronto, Canada.