EGF receptor
EGFR in C. elegans
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Interaction between EGFR receptor subtypes
Interaction of EGFs with EGF receptor
Activation of EGF receptor by dimerization
A single ligand is sufficient to activate EGFR dimers
Localized and global activation of EGFR
Inhibition of EGFR by Kekkon
Additional mechanisms for EGFR activation
Autoinhibition of EGFR
Recycling, endocytosis and dowregulation of EGFR
EGFR mutation and interspecies substitution
EGFR, cell migation, axon development and axon guidance
Direct substrates of EGFR
Interaction of EGFR with actin and Src
Signaling downstream of EGFR
Intracellular feedback on EGFR activity
Regulation of the EGF-R promoter
Epidermal growth factor signaling induces behavioral quiescence in Caenorhabditis elegans
EGFR and neural stem cells
Neuregulin1/ErbB4 signaling induces cardiomyocyte proliferation and repair of heart injury
EGFR, cell fate, differentiation and cell transformation
EGF receptor
:
Biological Overview
| Regulation
| Protein Interactions
| Developmental Biology
| Effects of Mutation
| References
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