Postdoctoral Position on Gene Editing and Bioreactor Liver Chip Technologies, University of Pittsburgh School of Medicine

Posted 5/6/2021

The laboratory of Dr. Samira Kiani at the University of Pittsburgh is looking for a postdoc candidate to join a collaborative research program on gene editing and bioreactor liver chip technologies.

Kiani lab uses the designer DNA binding proteins such as CRISPR and Zinc Finger proteins to develop novel gene and (epi)-gene-editing tools to address human diseases. We work with Liver on a Chip platform, a 3D perfusable system that allows us to develop and maintain human liver tissue over an extended period. The goal is to develop biomarkers and predict response to gene editing in human tissues.

We have contributed to the development of efficient CRISPR-based transcriptional repressors (Nat Methods. 2018 Aug;15(8):611-616), strategies to control gRNAs from RNA Pol II promoter (ACS Synth Biol. 2018 Aug 17;7(8):1929-1936) CRISPR layered control circuits (https://doi.org/10.1101/360198).

Minimum/Basic Qualifications: Experience in any of the following: standard molecular biology techniques including PCR, gel electrophoresis, mammalian cell culture maintenance, viral vectors. Experience with qPCR, ELISAs, and confocal microscopy. MD or Ph.D. in genetics, microbiology, biology, bioengineering, molecular biology, and/or cell biology. A good track record of publications is required.

Contact: Dr. Samira Kiani (samira.kiani@pitt.edu) with CV, cover letter, and contact information of at least two referees.

Last Updated 05/06/2021