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SDB 60th Annual Meeting Program July 18-22, 2001 University of Washington, Seattle, WA
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| Numbers in Italics indicate Program Abstract Number. | |||
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Wednesday July 18th |
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| 1-5pm | Meeting Registration at the dorms | Haggett | |
| 5-7pm | Dinner | McMahon | |
| 7-9:00pm | Presidential Symposium Analysis of Complex Systems |
HUB Ballroom | |
| Chair: | Brigid Hogan |
| 7:00 | Brigid Hogan (Vanderbilt
Medical School) Introduction |
| 7:05 | Linda Buck (Harvard
Medical School) The molecular architecture of odor and pheromone perception |
| 1 | 7:45 | Joanne Chory (Salk
Institute) Steroid hormones in plant development |
| 8:25 | Jay Hirsh (University
of Virginia) Bugs on drugs: Fruit flies as a model system for studying cocaine responsiveness |
| 9-11pm | Opening Reception and set up for Poster Session I | Upper Husky Den |
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Thursday July 19th |
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| 8am-5pm | Meeting Registration |
Kane Lobby |
| 8-9am | Funding Opportunities in Developmental Biology |
Kane 110 |
| Moderator: | Ida Chow (Society
for Developmental Biology) Domestic resources and international collaboration opportunities Agencies: NSF, NIH, MOD, HFSP |
| 8-9am |
Biotech Tutorial |
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| 9am-12:15pm | Concurrent Symposia with 15 min coffee break around 10:30am |
| 1. Cell Interactions and Signaling Pathways 1 | Kane 120 |
| Chair: | Philippe Soriano |
| 2 | 9:00 | Philippe
Soriano (Fred Hutchinson Cancer Research Center) PDGF Signaling in mouse development |
| 3 | 9:30 | Suzanne
Mansour (University of Utah) Fibroblast growth factors in ear development |
| 4 | 9:45 | Mark Krasnow (Stanford
Medical School) Genetic dissection of epithelial branching and oxygen response pathways in Drosophila |
| 5 | 10:15 | Laurel
Raftery (Massachusetts General Hospital) BMP and Sog-dependent thresholds of Smad activation during Drosophila dorsal-ventral patterning |
| 10:30 | Break |
| 10:45 | Jeff
Wrana (Samuel Lunenfeld Res. Inst., Canada) Interpreting TGFß and BMP signals during early development |
| 6 | 11:15 | Dominic
Norris (Harvard University) A nodal allelic series in the mouse |
| 7 | 11:30 | Malcolm
Whitman (Harvard Medical School) Nodal signals to Smads through Cripto-dependent and Cripto-independent mechanisms |
| 8 | 11:45 | Marek
Mlodzik (Mount Sinai School of Medicine) Non-canonical Frizzled signaling and epithelial planar polarity establishment |
| 2. Gametes: Formation and Function | Kane 110 |
| Chair: | Celeste Berg |
| 9 | 9:00 | Eleanor
Maine (Syracuse University) C. elegans ego-1 functions in germline development and RNAi |
| 10 | 9:30 | Erika Matunis
(Carnegie Institution of Washington) Jak Stat signaling controls male germline and somatic stem cell fate in Drosophila |
| 9:45 | Daphne
Preuss (University of Chicago) Mating interactions in Arabidopsis � signaling and species-specificity |
| 11 | 10:00 | Uta Wolke (Max-Planck
Institute, Germany) Multiple different modes of zebrafish VASA regulation |
| 10:30 | Break |
| 12 | 10:45 | Celeste
Berg (University of Washington) Multiple signaling pathways contribute to patterning and morphogenesis of the Drosophila egg |
| 13 | 11:15 | Karen
Bennett (University of Missouri-Columbia) Identifying C. elegans GLH partners by yeast two hybrid assays |
| 11:30 | Chris
Wylie (University of Cincinnati) Germ cells in the early mouse embryo |
| 14 | 12:00 | York
Marahrens (UCLA) Role of transvection in X-inactivation |
| 3. Cell Motility and Guidance | Kane 210 |
| Chair: | Lilianna Solnica-Krezel |
| 15 | 9:00 | Jeff
Hardin (University of Wisconsin-Madison) Molecular mechanisms regulating migration and adhesion of epithelial sheets in the C. elegans embryo |
| 16 | 9:30 | Erik
Lundquist (University of Kansas-Lawrence) Differential roles of Rac GTPase in axon pathfinding and cell corpse phagocytosis in C. elegans |
| 17 | 9:45 | Lilianna
Solnica-Krezel (Vanderbilt
University) Genetic control of convergent extension movements during zebrafish gastrulation |
| 18 | 10:15 | Gilbert Weidinger
(Max Planck Institute, Germany) Attraction, active migration and clustering of zebrafish primordial germ cells |
| 10:30 | Break |
| 19 | 10:45 | Pernille
Rorth (European Molecular Biology Laboratory, Germany) Regulation of cell migration during Drosophila oogenesis |
| 20 | 11:15 | Dan
Mellott (University of Victoria, Canada) ephB1 receptor and ephrins guide the migration of avian hindbrain neural crest |
| 21 | 11:30 | Darren
Gilmour (Max Planck Institute, Germany) A neural crest derived glial lineage in the zebrafish: coupling in vivo imaging and genetic analysis |
| 11:45 | Peter Devreotes
(Johns Hopkins University) Chemotactic gradient sensing in eucaryotic cells |
| 12:30-1:30pm | Lunch | McMahon |
| 1:30-3:30pm | Education
Workshop Ethics |
HUB Ballroom |
| Chair: | Karen Crawford |
| 1:30 | Mary
Claire King (University of Washington) Genomic views of human history |
| 22 | 2:00 | Anne
McLaren (University of Cambridge, U.K.) Human embryo and stem cell research: A view from Europe |
| 2:30 | Karen
Crawford (St. Mary's College of Maryland) - Moderator Discussion |
| 1:30-4pm | Poster Session I | Upper Husky Den |
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Numbers in Italics
indicate the Program Abstract Number. Odd number boards: Authors
present at posters 1:30-3pm |
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Cell Biology and
Development 24 B2 The dynamic cell wall of Acetabularia. E. Dunn, R. Froisland, M.E. Moffet, S. Mehri, N. Carpita, X. Huang, R. Kline, A. Mackay, M. Madison, I. Taylor, Z. Yang, G. Odell and D. Mandoli. Univ. of Washington, Seattle, WA, Purdue Univ., W. Lafayette, IN, Univ. of British Columbia, Canada and Univ. of California, Riverside, CA. 25 B3 Morpholino antisense-mediated depletion of SpRunt-1 causes mitotic abnormalities and late cleavage-stage arrest in sea urchin embryos. J.A. Coffman, S.J. Morris and C.W. Thurm. Stowers Inst. for Med. Res., Kansas City, MO. 26 B4 Incorporation of wheat germ agglutinin into the calcitic spicule of developing sea urchin embryos. N.M. Mozingo. Miami Univ., Oxford, OH. 27 B5 The role of the cytoskeleton during cytoplasmic cap formation and early cleavage in the squid, Loligo pealei. K. Crawford. St. Mary's Col. of Maryland, St. Mary's City, MD. 28 B6 Withdrawn 29 B7 Gurken- and microtubule-independent polarization of the Drosophila oocyte; rab11-mediated organization of the posterior pole. G.L. Dollar, E. Struckhoff, J. Michaud and R.S. Cohen. Univ. of Kansas, Lawrence, KS. 30 B8 Conserved signals and machinery for asymmetric RNA localisation in Drosophila oocytes and embryos. S.L. Bullock and D. Ish-Horowicz. Imperial Cancer Res. Fund, London, UK. 31 B9 Cytoskeleton networks affect Cdk1-cyclin B activities in the syncytial Drosophila embryo. J.Y. Ji, C. Trusty, C. Beach and G. Schubiger. Univ. of Washington, Seattle, WA. 32 B10 Rho1 is required for localization of adherens junction components during Drosophila development. C.R. Magie, D. Pinto-Santini and S.M. Parkhurst. Fred Hutchinson Cancer Res. Ctr., Seattle, WA. 33 B11 Characterization of a novel dominant allele of the roughest-irregular chiasm C gene shows its requirement for pigment cell fate determination in the Drosophila retina. S. Octacilio-Silva, H. Araujo, L.C.H. Machado and R.G.P. Ramos. Ribeirão Preto Med. Sch., São Paulo, Brazil. 34 B12 Steroid regulation of programmed cell death during Drosophila development. C. Lee, C.R. Simon and E.H. Baehrecke. Univ. of Maryland, College Park, MD. 35 B13 Transcription factors E75 and MHR3 display a mosaic response to rising titers of ecdysone in Manduca epidermis. R.E. Langelan, K. Hiruma and L.M. Riddiford. Univ. of Washington, Seattle, WA. 36 B14 Spindle rotation in the early C. elegans embryo. A.J. Wright and C.P. Hunter. Harvard Univ., Cambridge, MA. 37 B15 Unraveling the role of calcium signaling in the early embryo. J.M. Squirrell, J. Ji, J.W. Walker and J.G. White. Univ. of Wisconsin, Madison, WI and Univ. of Washington, Seattle, WA. 38 B16 Cell cycle control during Xenopus tropicalis oocyte maturation. J-F. Bodart, D. Gutierrez and N. Duesbery. Van Andel Res. Inst., Grand Rapids, MI. 39 B17 Effects of localized acto-myosin contraction in Xenopus laevis oocytes. J. Thorn and B. Kay. Knox Col., Galesburg, IL and Univ. of Wisconsin, Madison, WI. 40 B18 Segregation of zebrafish muscle lineages: lineage relationships and cellular commitment. E. Hirsinger and M. Westerfield. Univ. of Oregon, Eugene, OR. 41 B19 When and where do zebrafish slow muscle precursors stop dividing? J.A. D'Angelo, M.J.F. Barresi and S.H. Devoto. Wesleyan Univ., Middletown CT. 42 B20 How your muscles know you've been working out: the IP3 pathway as a developmental signal in skeletal muscle. J.A. Powell, M.A. Carrasco, D.S. Adams, B. Drouet, J. Rios, M. Muller, M. Estrada, and E. Jaimovich. Smith Col., Northampton, MA, Univ. of Chile, Santiago, Chile and INSERM U-505, Paris, France. 43 B21 Bone morphogenetic protein function is required for the initial myofibrillogenesis in chick cardiogenesis. Y. Nakajima, T. Yamagishi and H. Nakamura. Saitama Med. Sch., Saitama, Japan. 44 B22 The zebrafish inv gene is required for left-right brain and heart development. J.J. Essner, X.-H. Wang, J. Zhang and H.J. Yost. Univ. of Utah, Salt Lake City, UT. 45 B23 Fates of neural crest cells in zebrafish Waardenburg-Shah model colourless/sox10 mutant. K.A. Dutton and R.N. Kelsh. Univ. of Bath, Bath, UK. 46 B24 Zebrafish mosaic eyes gene is required for tight junction formation in the retinal pigmented epithelium. A.M. Jensen and M. Westerfield. Univ. of Oregon, Eugene, OR. 47 B25 BMP11-a candidate negative regulator of olfactory neurogenesis. H.-H. Wu, P. Chern, J.E. Johnson and A.L. Calof. Univ. of California, Irvine, CA and Univ. of Texas Southwestern, Dallas, TX. 48 B26 Insulin-like growth factor-II modifies cell survival and proliferation during a discrete period of mouse embryogenesis. J.L. Burns and A.B. Hassan. Univ. of Oxford, Oxford, UK. 49 B27 Immunohistochemical localization of leukemia inhibitory factor, interleukins 1α, 1β and IL-6 in embryo-endometrium interface during implantation in the rhesus monkey. L. Dhawan, D. Ghosh and J. Sengupta. All India Inst. of Med. Sci., New Delhi, India. 50 B28 Exposure of human ES cells to TGF beta family members alters endoderm and mesoderm differentiation in vitro. M.T. Firpo, C. Ayala, C. Catuar, J.J. Meneses, G. Perez and R.A. Pedersen. Univ. of California, San Francisco, CA. Cell Interactions 51 B29 The role of callose in root gravitropism. L.C. Enns, R.E. Cleland, K.U. Torii and L. Comai. Univ. of Washington, Seattle, WA. 52 B30 Peripodial membrane cells regulate imaginal disc development in Drosophila. M.C. Gibson and G. Schubiger. Univ. of Washington, Seattle, WA. 53 B31 Functional characterization of the Lim1 gene during gastrulation. N.A. Hukriede, D.L. Weeks and I.B. Dawid. NICHD, NIH, Bethesda, MD and Univ. of Iowa, Iowa City, IA. 54 B32 Early pregnancy factor in embryonic development and during pregnancy in the dasyurid marsupial, Sminthopsis macroura (Spencer). Y.P. Cruz, L. Selwood, H. Morton and A.C. Cavanagh. Oberlin Col., Oberlin, OH, Univ. of Melbourne, Melbourne, Australia and Univ. of Queensland, Brisbane, Australia. 55 B33 Survey of surface characteristics of human cancer cells using derivatized agarose beads. G.R. Weerasinghe, M.R. Khurrum, E.S. Soriano, O. Badali, T. Sakhakorn, L. Kirszenbaum, L. Ngo, K. Abedi, C. Harieg, V.M. Navarro, M. Barajas, A. Martino, D. Toledo, J. Ching, M.W. Soccar, D. Khatibi, R. Riman, C.A. Bulan, G. Zem, K.M. Cork, S. Meshkinfam, R. Nejathaim and S.B. Oppenheimer. California State Univ., Northridge, CA. Cell Motility and Guidance 56 B34 Filopodial initiation and a novel filament organizing center, the focal ring. K.W. Tosney, K. Balazovich and M. Steketee. Univ. of Michigan, Ann Arbor, MI. 57 B35 Morphogenetic domains and their ontogeny in the zebrafish gastrula. M.S. Cooper and L.A. D'Amico. Univ. of Washington, Seattle, WA. 58 B36 Stuck in place is a new locus required for proper cell migration in Drosophila. J.A. McDonald and D.J. Montell. Johns Hopkins Univ. Sch. of Med., Baltimore, MD. 59 B37 Identification of genes controlling longitudinal guidance in the nematode C. elegans. A. Adeleye, F. Vedulla and E. Stringham. Trinity Western Univ., Langley, Canada. 60 B38 The regulation of bud elongation and branching program initiation during lacrimal gland development. H. Makarenkova and R. Lang. Skirball Inst., NYU Sch. of Med., New York, NY. 61 B39 Hindbrain neural crest cells require integrins for epithelial-mesenchyme transition, but not for pathfinding. R.L. Atkins, D. Wang and R.D. Burke. Univ. of Victoria, Victoria, Canada. 62 B40 Avian neural crest migration guidance, from microns to millimeters. A.J. Ewald and S.E. Fraser. Caltech, Pasadena, CA. 63 B41 Quantitative analysis of germ cell movements in tissue explants. K.A. Molyneaux, K. Schaible and C. Wylie. Children's Hosp., Cincinnati, OH. 64 B42 Regulation of Doublecortin, a protein implicated in cortical neuron migration. B.T. Schaar, K. Kinoshita, A. Hyman and S.K. McConnell. Stanford Univ., Stanford, CA and Max Planck Inst. of Mol. Cell Biol. and Genet., Dresden, Germany. Body Plan 65 B43 Embryonic handedness choice in C. elegans involves a Gα protein encoded by the spn-1 gene. W.B. Wood, B. Robertson and D. Bergmann. Univ. of Colorado, Boulder, CO. 66 B44 Spatial expression patterns of Hox genes during development of the sepiolid squid, Euprymna scolopes. P.N. Lee, P. Callaerts, B. Hartmann, D. Choy, M.Q. Martindale and H.G. de Couet. Univ. of Hawaii at Manoa, Honolulu, HI. 67 B45 A sensitized haploid screen for zebrafish gastrulation mutants. D.H. Lee, F.A. Olale, T. Bruno, D. Yelon and A.F. Schier. Skirball Inst., NYU Sch. of Med., New York, NY. 68 B46 Pitx2c-gfp trangenic zebrafish identify regions of asymmetric gene expression in the central nervous system. H.J. Yost, E.B. Harris and J.J. Essner. Univ. of Utah, Salt Lake City, UT. 69 B47 Arkadia is essential for specification of antero-posterior and left-right axes. P.M. Timmons, R.L. Andrew, J.J. Walsh, D. Swan, R. Arkell and V. Episkopou. MRC Clin. Sci. Ctr., London, UK. 70 B48 Withdrawn 71 B49 Inadequate differentiation of endoderm/mesoderm derived cells in mouse l7Rn3 mutant embryos. H. Nakamura, S.E. Thomas and M.J. Justice. Baylor Col. of Med., Houston, TX. 72 B50 Functional analyses of bone morphogenetic proteins during pattern formation and organogenesis in mouse embryos. Y. Mishina, C. Trisha and S. Kishigami. Natl. Inst. of Envrn. Hlth. Sci., NIH, Res. Triangle Park, NC. 73 B51 Evidence that delta and forkhead genes interact during somitogenesis in the mouse. B. Wilm and B.L.M. Hogan. Vanderbilt Univ. Sch. of Med., Nashville, TN. 74 B52 The role of midline FGF8 in left-right axis specification in the rabbit. M. Blum and A. Fischer. Forschungszentrum Karlsruhe, Karlsruhe, Germany. Morphogenesis 75 B53 Complete live Drosophila embryogenesis: time-lapse movie of histone-GFP embryos with multiphoton microscopy. J.Y. Ji, J. Squirrell, D. Hurley and G. Schubiger. Univ. of Washington, Seattle, WA and Univ. of Wisconsin, Madison, WI. 76 B54 Genetic analysis of isometric growth in the zebrafish. M.K. Iovine and S.L. Johnson. Washington Univ. Sch. of Med., St. Louis, MO. 77 B55 Growth control in the zebrafish, Danio Rerio. M.I. Goldsmith, R. Waterman and S.L. Johnson. Washington Univ. Sch. of Med., St. Louis, MO. 78 B56 Zebrafish Paxillin and FAK are necessary for normal development. C.A. Henry, B.D. Crawford and M.B. Hille. Univ. of Washington, Seattle, WA. 79 B57 One-eyed pinhead dependent cell behavior in the zebrafish blastula. R.M. Warga and D.A. Kane. Univ. of Rochester, Rochester, NY. 80 B58 A relationship of epiboly with other cellular movements in the zebrafish gastrula. D.A. Kane, K.N. DelKanic and R.M. Warga. Univ. of Rochester, Rochester, NY. 81 B59 Cell internalization during zebrafish gastrulation. A.J. Carmany-Rampey and A.F. Schier. Skirball Inst., NYU Sch. of Med., New York, NY. 82 B60 3D-time lapse analysis of Xenopus gastrulation movements using μMRI. C. Papan, S.S. Velan, S.E. Fraser and R.E. Jacobs. Beckman Inst., California Inst. of Technol., Pasadena, CA. 83 B61 The role of the Rho GTPases in controlling cell movements: a close look into the fine mechanics of Xenopus gastrulation. E. Tahinci and K. Symes. Boston Univ. Sch. of Med., Boston, MA. 84 B62 Involvement of PAR-6 in the regulation of gastrulation cell movement in Xenopus early development. S-C. Choi and J-K. Han. Pohang Univ. of Sci. and Technol., Pohang, Republic of Korea. 85 B63 Migration and mechanics during closure of the mesendodermal mantle in Xenopus laevis. L.A. Davidson, R. Keller and D.W. DeSimone. Univ. of Virginia Hlth. Syst., Sch. of Med., Charlottesville, VA. 86 B64 Cell autonomous effect of the Wnt pathway in Spemann organizer formation in Xenopus laevis. A. Vonica and B.M. Gumbiner. Sloan-Kettering Inst., New York, NY. 87 B65 Identifying neurulation genes in chick. J-F. Colas and G.C. Schoenwolf. Univ. of Utah Sch. of Med., Salt Lake City, UT. 88 B66 Exploring a genetic basis for neurulation in zebrafish. R.M. Brewster, A.L. Rubinstein and M.E. Halpern. Carnegie Inst. of Washington, Baltimore, MD. 89 B67 A role for midline signalling in neural convergence and extension. C.M. Scott-Whitlow, C.R. Heitz and R.E. Keller. Univ. of Virginia, Charlottesville, VA. 90 B68 The role of the AP-2α transcription factor in ventral body wall closure. S.L. Brewer, S. Donaldson and T. Williams. Yale Univ., New Haven, CT and Univ. of Colorado Hlth. Sci. Ctr., Denver, CO. 91 B69 Epithelial-mesenchymal transition and neural crest differentiation: several routes to one outcome. D.F. Newgreen, S. Lewis and J. Minichiello. Murdoch Childrens Res. Inst., Parkville, Australia. 92 B70 Neural crest cell motility in valproic acid. D. Wiens, L. Fuller and S. Cornelius. Univ. of Northern Iowa, Cedar Falls, IA. 93 B71 Genetic dissection of c-kit function during embryonic melanocyte development in the zebrafish. J.F. Rawls and S.L. Johnson. Washington Univ. Sch. of Med., St. Louis, MO. 94 B72 The flat top mutation affects the differentiation of post-otic neural crest. T.H. Linbo, C.B. Moens and D.W. Raible. Univ. of Washington, Seattle, WA and Fred Hutchinson Cancer Res. Ctr., Seattle, WA. 95 B73 Time-lapse analysis of somite formation in whole chick embryo explants. P.M. Kulesa and S.E. Fraser. California Inst. of Technol., Pasadena, CA. 96 B74 Contribution of somitic cells to the avian axial skeleton and hypaxial musculature. D.J.R.Evans. Cardiff Univ., Cardiff, Wales, UK. 97 B75 Dorsal, axial morphogenesis, deposition of the ECM protein fibrillin, and sonic hedgehog expression are all dependent on the notochord-somite boundary. P. Skoglund, A. Rolo and R.E. Keller. Univ. of Virginia, Charlottesville, VA. 98 B76 The upstream ectoderm enhancer in Pax6 has an important role in lens induction. P.V. Dimanlig and R.A. Lang. Skirball Inst. for Biomolec. Med., New York Univ. Sch. of Med., New York, NY. 99 B77 Chondrogenesis of the otic capsule during the chicken inner ear development. W. Chang, P. ten Dijke and D.K. Wu. NIDCD/NIH, Rockville, MD and The Netherlands Cancer Inst., Amsterdam, The Netherlands. 100 B78 Mechanisms of left-right asymmetric digestive organ morphogenesis. J.L. Keene, D.R. Knutson and N.M. Nascone-Yoder. Eckerd Col., St. Petersburg, FL. 101 B79 The Ret signaling system and pronephric duct migration in axolotl and Xenopus embryos. J. Drawbridge, M.E. Kite, C.M. Meighan and R. Lumpkins. Rider Univ., Lawrenceville, NJ. 102 B80 Evidence that SPROUTY2 functions as an inhibitor of mouse embryonic lung growth and morphogenesis. A. Mailleux, D. Tefft, D. Ndiaye, N. Itoh, J-P. Thiery, D. Warburton and S. Bellusci. CNRS/Institut Curie, Paris, France, Childrens Hosp. Los Angeles Res. Inst., Univ. of Southern California, Los dAngeles, CA and Kyoto Univ., Kyoto, Japan. B 103 B81 Absence of ventricular ballooning segments in embryos lacking the homeobox gene Nkx2-5. C. Biben, L. McDonald and R.P. Harvey. Victor Chang Cardiac Res. Inst., Darlinghurst, Australia. 104 B82 Withdrawn 105 B83 Characterization of the roles of a novel T-box transcription factor, hrT, during cardiovascular development in zebrafish. D.P. Szeto, K.J.P. Griffin and D. Kimelman. Univ. of Washington, Seattle, WA. 106 B84 Distinct mechanisms regulate slow muscle development during the embryonic and larval periods. M.J.F. Barresi, J.A. D'Angelo, L.P. Hernandez and S.H. Devoto. Wesleyan Univ., Middletown, CT. 107 B85 A new semi-dominant mutation linked to Shh causes preaxial polydactyly. J.O. Bush and R.J. Jiang. Univ. of Rochester Sch. of Med. and Dent., Rochester, NY. 108 B86 Engrailed1 is critical for repression of nail type differentiation in mouse. P. Kraus, C. Tong and C.A. Loomis. NYU Sch. of Med., New York, NY. 109 B87 Surprising expression pattern of cholesterogenic enzymes during embryonic mouse development. D. Laubner, R. Breitling and J. Adamski. GSF, Natl. Res. Ctr., Neuherberg, Germany. 110 B88 DWnt-4 cooperates with Dfrizzled-2 to regulate cell motility during ovarian morphogenesis. E.D. Cohen and E. Wilder. Univ. of Pennsylvania Sch. of Med., Philadelphia, PA. 111 B89 Genetic screen identifies Bicaudal-C, Kinesin heavy chain, and Shark as enhancers of bullwinkle. D.H. Tran and C.A. Berg. Univ. of Washington, Seattle, WA. 112 B90 Planarian regeneration: a classic problem enters the era of functional genomics.. P.A. Newmark, S. Robb, R. Juste, S. Saha and A. Sanchez Alvarado. Carnegie Inst. of Washington, Baltimore, MD. 113 B91 Pharynx tubulogenesis during C. elegans development. M.F. Portereiko and S.E. Mango. Univ. of Utah, Salt Lake City, UT. 114 B92 Development of the Acetabularia acetabulum vacuole: a model for vacuolar morphogenesis and inheritance. P.A. Garland, D. Ngo, P. Luethe and D. Mandoli. Univ. of Washington, Seattle, WA. 115 B93 The invA gene of Volvox encodes a novel kinesin that is required for inversion of the embryo. I. Nishii and D.L. Kirk. Washington Univ., St. Louis, MO. Organogenesis 116 B94 Regulation of organ shape in Arabidopsis by ERECTA receptor-like kinase. E.D. Shpak, C.A.B. Josefsson and K.U. Torii. Univ. of Washington, Seattle WA. 117 B95 Specification of organ identity by the C. elegans FoxA protein PHA-4. J. Gaudet, M. Horner, S. Kim and S.E. Mango. Univ. of Utah, Salt Lake City, UT and Stanford Univ. Med. Sch., Stanford, CA. 118 B96 Molecular integration of signaling activities and tissue-specific transcription factors during visceral mesoderm specification of Drosophila. H.H. Lee, S. Zaffran and M. Frasch. Mount Sinai Sch. of Med., New York, NY. 119 B97 BMP signaling is important for mesoderm specification and regulation of neurectoderm growth in mouse embryonic development. S. Miura, M.D. Tallquist, P. Soriano and Y. Mishina. NIEHS/NIH, Research Triangle Park, NC and Fred Hutchinson Cancer Res. Ctr., Seattle, WA. 120 B98 Chick-quail chimerism proves the mesenchymal origin of bursal secretory dendritic cell. N. Nagy, A. Magyar and I. Olah. Semmelweis Univ., Budapest, Hungary. 121 B99 Tissue-specific knockout of smoothened reveals a critical role for hedgehog signaling in chondrocyte proliferation. F. Long, X. Zhang and A.P. McMahon. Harvard Univ., Cambridge, MA. 122 B100 Study on the role of epidermal growth factor in chondrogenesis. K.M. Ng, S.E. Cheah, W.C. Wong and S.Y. Chan. Univ. of Hong Kong, Hong Kong, China and Univ. of Tokyo, Tokyo, Japan. 123 B101 Commitment and differentiation of avian head muscles. D. Noden, X. Borue and R. Marcucio. Cornell Univ., Ithaca, NY and Univ. of California, San Francisco, CA. 124 B102 Evolutionary conservation of Hoxc13. R. Thummel, M.P. Sarras and A.R. Godwin. Univ. of Kansas Med. Ctr., Kansas City, KS. 125 B103 Rescue of cleft palate in Msx1-deficient mice by transgenic Bmp4 reveals a role of BMP and SHH signaling in mammalian palatogenesis. Z. Zhang, Y. Song, X. Zhao, X. Zhang and Y. Chen. Tulane Univ., New Orleans, LA. 126 B104 Wnt pathway members in the development of hair and other skin appendages. U. Gat, B.J. Merrill and E. Fuchs. Hebrew Univ., Jerusalem, Israel and Univ. of Chicago, Chicago, IL. 127 B105 The role of Msx1 and Bmp4 in digit tip regeneration of mice. M. Han and K. Muneoka. Tulane Univ., New Orleans, LA. 128 B106 Genetic analysis of zebrafish fin regeneration. K.D. Poss, A. Nechiporuk, S.L. Johnson and M.T. Keating. Children's Hosp., Boston, MA and Washington Univ., St. Louis, MO. 129 B107 A role for the LIM-domain co-factors Clim2/Ldb-1/Nli in hair follicle regulation. E.I. Kudryavtseva, I. Chen, T.M. Sugihara and B. Andersen. UCSD, La Jolla, CA and UCI, Irvine, CA. 130 B108 Overexpression of a soluble dominant negative FGFR1 and SPRY2 affects craniofacial and feather development. M. Mandler and A. Neubuser. Inst. of Molec. Pathol., Vienna, Austria. 131 B109 In vitro studies of the discrete steps in the development of mouse Rathke's pouch. A.S. Gleiberman, E.I. Kudryavtseva and M.G. Rosenfeld. UCSD, La Jolla, CA. 132 B110 Pitx2 is required at multiple stages of pituitary organogenesis: formation of the pituitary primoridum and cell specification. H. Suh, P.J. Gage, J. Drouin and S.A. Camper. Univ. of Michigan, Ann Arbor, MI and Inst. of Clin. Res., Montreal, Canada. 133 B111 Dorsal-ventral patterning in Xenopus inner ear: ablation and Wnt-3a studies. C.A. Forristall and A. Collazo. Univ. of Redlands, Redlands, CA and House Ear Inst., Los Angeles, CA. 134 Withdrawn 465* B112 Ras1 is required cell autonomously in the Drosophila follicular epithelium for pipe repression and dorsal follicle cell migration. K.E. James and C.A. Berg. Univ. of Washington, Seattle, WA. * Poster moved from Poster Session II, B175 135 B113 Withdrawn 136 B114 The role of Eya genes during mammalian organogenesis. P. Xu, R. Maas, C. Buller, H. Peters and X. Xu. McLaughlin Res. Inst., Great Falls, MT. 137 B115 FGF receptor and BMP7 signaling cooperate in lens induction. S.C. Faber, H.P. Makarenkova, P. Dimanlig and R.A. Lang. Skirball Inst. and New York Univ. Med. Ctr., New York, NY. 138 B116 A role for sonic hedgehog in fetal thymus development. B.A. Moore and N.R. Manley. Med. Col. of Georgia, Augusta, GA. 139 B117 ITIH-4, a serine protease inhibitor plays a prominent functional role in IL-6 induced hepatocyte formation. C. Banumathy, Y. Tang, C. Fox, B. Mishra and L. Mishra . DVAMC, Washington, DC and Fels Cancer Inst., Temple Univ., Philadelphia, PA, NHGRI, NIH, Bethesda, MD and Walter Reed Army Med. Ctr., Washigton, DC. 140 B118 Expression of Prox1 during liver development. Z.D. Burke, B. Sosa-Pineda, J. Wigle and G. Oliver. Saint Jude Children's Res. Hosp., Memphis, TN. 141 B119 The roles of FGFs, BMP4, and SHH in transdifferentiation of mouse tracheal epithelium in mesenchyme-free culture. B.A. Hyatt, J.A. Whitsett and J.M. Shannon. Children's Hosp. Med. Ctr., Cincinnati, OH. 142 B120 Hlx homeobox transcription factor downstream targets identified in Hlx knockout mesenchymal cell lines. M.D. Bates, D.A. Persons, L.C. Schatzman, R.P. Harvey, and S.S. Potter. Children's Hosp. Med. Ctr., Cincinnati, OH, St. Jude Children's Res. Hosp., Memphis, TN, and St. Vincent's Hosp., Darlinghurst, Australia. 143 B121 The homeobox gene Hex is necessary for liver and lung development. C.W. Bogue, C.M. Wilson, H. Vasavada and H.C. Jacobs. Yale Univ. Sch. of Med., New Haven, CT. 144 B122 The correct regional specification and function of the stomach requires mesenchymal-epithelial signaling cascades controlled by Hoxa5. J. Aubin, U. Dery, P. Chailler and L. Jeannotte. Univ. Laval, Univ. of Quebec, L'Hotel-Dieu de Quebec, and Univ. of Sherbrooke, Quebec, Canada. 145 B123 Using a novel gut culture system to analyse the influence of known and novel genes on intestinal epithelial differentiation. H.E. Abud, C.N. Johnstone, N. Watson, N.C. Tebbutt, M. Ernst and J.K. Heath. Ludwig Inst. for Cancer Res., Royal Melbourne Hosp., Melbourne, Australia. 146 B124 A new Abd-B class homeobox gene (HgHbox12) from an echinoderm, and its expression during intestinal regeneration. A.T. Mendez-Merced and J.E. Garcia-Arraras. Univ. of Puerto Rico, Rio Piedras, Puerto Rico. 147 B125 Two actin isoforms are differentially expressed during regenerative organogenesis in the echinoderm Holothuria glaberrima. J.L. Roig-Lopez, C. Lasalde and J.E. Garcia-Arraras. Univ. of Puerto Rico-Rio Piedras, San Juan, PR. 148 B126 Notochord and endothelial signals during patterning of the Xenopus endoderm. O. Cleaver and D. Melton. Harvard Univ., Cambridge, MA. 149 B127 Gata4 and Gata6 function in the mouse embryonic pancreas. D.C. Goldman and L. Sussel. Univ. of Colorado Hlth. Sci. Ctr., Denver, CO. 150 B128 Cloning and functional characterization of Xenopus Pod-1, a bHLH transcription factor expressed in the developing pronephric kidney. S.R. Eid and A.W. Brandli. Swiss Fed. Inst. of Technol., Zurich, Switzerland. 151 B129 The biology of becoming: cell fate decisions during embryonic kidney development. K.A. McLaughlin, M.S. Rones and M. Mercola. Harvard Med. Sch., Boston, MA. 152 B130 Differential regulation of pax2 and lim1 in the chick embryonic kidney. R.G. James and T.M. Schultheiss. Beth Israel Deaconness Med. Ctr., Boston, MA. 153 B131 Visualization of kidney branching morphogenesis. T. Watanabe, S. Srinivas, C.S. Lin, R. Shakya and F. Costantini. Columbia Univ., New York, NY and Natl. Inst. of Med. Res., London, UK. 154 B132 Regulation of metanephric kidney development by Gdf-11. A. Esquela Kerscher, A. McPherron and S-J. Lee. Johns Hopkins Sch. of Med., Baltimore, MD. 155 B133 Role of the transcription factors Pax2 and Pax8 in nephric lineage determination. M. Bouchard, A. Souabni and M. Busslinger. Inst. for Molec. Pathol., Vienna, Austria. 156 B134 The role of Wnts in the development of the kidney collecting ducts. T.J. Carroll, M. Ishibashi, B. Parr and A.P. McMahon. Harvard Univ., Cambridge, MA. 157 B135 The role of sonic hedgehog during mouse kidney development. J. Yu, T.J. Carroll, P.M. Lewis and A.P. McMahon. Harvard Univ., Cambridge, MA. 158 B136 Kidney development depends on a novel reciprocal signaling loop mediated by vitamin A and ret. E. Batourina, S. Gim, N. Bello, M. Shy, M. Clagett-Dame, S. Srinivas, F. Costantini and C. Mendelsohn. Columbia Univ., New York, NY, Univ. of Wisconsin-Madison, Madison, WI and Natl. Inst. for Med. Res., Mill Hill, London, U.K. 159 B137 Functional characterization of the Hey bHLH gene family. M. Gessler, K. Knobeloch, N. Schumacher, K. Amann, N. Golenhofen and C. Leimeister. Univ. of Wuerzburg, Wuerzburg, Germany, Freie Univ., Berlin, Germany and Univ. of Erlangen, Germany. 160 B138 A role for XWnt-11 in Xenopus cardiogenesis. P. Pandur and M. Kuehl. Univ. of Goettingen, Goettingen, Germany. 161 B139 In vivo study of ANF regulation by Nkx2-5 and GATA-4 in transgenic Xenopus laevis embryos. E.M. Small and P.A. Krieg. Univ. of Arizona Hlth. Sci. Ctr., Tucson, AZ. 162 B140 Genetic regulation of myocardial differentiation in zebrafish. B.R. Keegan, R.K. Ho and D.L. Yelon. Skirball Inst. of Biomolec. Med., New York Univ. Med. Ctr., New York, NY and Princeton Univ., Princeton, NJ. 163 B141 Causes and consequences of an atrium-specific developmental defect in zebrafish. E. Berdougo, D.Y.R. Stainier and D. Yelon. Skirball Inst., New York Univ. Med. Ctr., New York, NY and Univ. of California at San Francisco, San Francisco, CA. 164 B142 A role for FGF signaling in the specification of avian heart tissue. T.M. Schultheiss and B.H. Alsan. Beth Israel Deaconess Med. Ctr., Harvard Med. Sch., Boston, MA. 165 B143 Cardiofunk, a zebafish mutation disrupting atrioventricular valve formation. T. Bartman and D.Y.R. Stainier. Univ. of California, San Francisco, CA. 166 B144 Bves: prototype of a new class of cell adhesion molecules expressed during coronary artery development. A.M. Wada, D.E. Reese and D.M. Bader. Vanderbilt Univ., Nashville, TN. 167 B145 The zebrafish gene pandora regulates myocardial differentiation. J.L. Feldman, D.Y.R. Stainier and D.L. Yelon. Skirball Inst. of Biomolec. Med., New York Univ. Med. Ctr., New York, NY and Univ. of California, San Francisco, San Francisco, CA. 168 B146 Notch signaling in left-right determination during mouse development. L.T. Krebs, I. Welsh, C.H. Tenney, Y. Lan, R. Jiang, T. O'Brien and T. Gridley. The Jackson Lab., Bar Harbor, ME. 169 B147 Development of the hematopoietic tissue in the Penaeid shrimp Sicyonia ingentis. P.L. Hertzler and O.J. Sepulveda Villet. Central Michigan Univ., Mt. Pleasant, MI. 170 B148 Hedgehog signaling and yolk sac vasculogenesis. N.A. Byrd, S. Becker, P.F. Maye, J.A. McMahon, X.M. Zhang, A.P. McMahon and L.B. Grabel. Wesleyan Univ., Middletown, CT, and Harvard Univ., Cambridge, MA. 171 B149 Endoderm is not necessary for vascular specification, but is necessary for endothelial tube formation. S.A. Vokes and P.A. Krieg. Univ. of Arizona Hlth. Sci. Ctr. Tucson, AZ. 172 B150 Intersomitic arteries and intersomitic veins form via distinct mechanisms. S. Isogai, N.D. Lawson, S. Torrealday and B.M. Weinstein. NICHD, NIH, Bethesda, MD. 173 B151 Notch signaling is required for arterial differentiation and repression of venous cell fate during embryonic vascular development. N.D. Lawson, N. Scheer, V.N. Pham, C-H. Kim, A.B. Chitnis, J.A. Campos-Ortega and B.M. Weinstein. NICHD, NIH, Bethesda, MD and Univ. of Koln, Cologne, Germany. 174 B152 Competing pathways in testis organogenesis. B. Capel, C. Tilmann, J. Schmahl, J. Brennan and H.H.C. Yao. Duke Univ. Med. Ctr., Durham, NC. 175 B153 Sex specific gene expression during mouse gonad development. D. Menke and D.C. Page. MIT, Cambridge, MA. 176 B154 The PDGF alpha receptor is required for interstitial specification and cord formation in the mammalian testis. C.E. Tilmann, J.R. Brennan and B. Capel. Duke Univ. Med. Ctr., Durham, NC. 177 B155 The role of FGF9 and proliferation in sex determination. J.P. Schmahl, J. Colvin, D. Ornitz and B. Capel. Duke Univ., Durham, NC. 178 B156 Direct evidence that Sry is expressed in pre-Sertoli cells and that Sertoli and granulosa cells develop from a common precursor. K.H. Albrecht and E.M. Eicher. Jackson Lab., Bar Harbor, ME. 179 B157 Sexually dimorphic vascular development in the XY mouse gonad. J.R. Brennan, and B. Capel. Duke Univ. Med. Ctr., Durham, NC. 180 B158 Decisive roles of meiotic germ cells in sex determination of mammalian gonads. H.H.C. Yao and B. Capel. Duke Univ. Med. Ctr., Durham, NC. 181 B159 Assessment of candidate ovarian determining genes. K.A. Loffler, J. Bowles and P. Koopman. Univ. of Queensland, Brisbane, Australia. 182 B160 Effects of acute nutritional stress during the pre-implantation stage of gestation on reproductive functions in the mouse. J.F. Rosario, J. Sengupta and D. Ghosh. All India Inst. of Med. Sci., New Delhi, India. 183 B161 An effects on teratogenicity by exposure with cyclophosphamide during early organogenic period. S.J. Kwack, H.S. Kim and K.L. Park. Natl. Inst. of Toxicol. Res., Seoul, Korea. Gametogenesis and Fertilization 184 B162 POP2, a gene required for guidance of Arabidopsis pollen tubes, is similar to class III omega aminotransferases. R. Palanivelu, L.K. Wilhelmi and D. Preuss. Univ. of Chicago, Chicago, IL. 185 B163 L-HGP, a heterodimeric mucin-like protein with acrosome protective properties. S.E. Arranz, R. Cabrera and M.O. Cabada. Univ. Nacional de Rosario, Rosario, Argentina. 186 B164 Identification of a sperm lysin in the frog Lepidobatrachus laevis. V. Hutchins-Latham and E.J. Carroll, Jr. California State Univ., Northridge, CA. 187 B165 Xenopus sperm display three swimming patterns: ideal corkscrew, uncoupled corkscrew, and idle. S. Naqvi, A. Kittelson and D.E. Chandler. Arizona State Univ., Tempe, AZ. 188 B166 Allurin, a 21 kD sperm chemoattractant from Xenopus egg jelly, is related to mammalian sperm-binding proteins of the CRISP family. X. Xiang, J. Olson, J. Johnson, A. Rawls, A.L. Bieber and D.E. Chandler. Arizona State Univ., Tempe, AZ. 189 B167 Isolation of allurin, a 21 kD sperm chemoattractant protein from Xenopus laevis egg jelly: purification and characterization. J.H. Olson, X. Xiang, T. Ziegert, A. Kittelson, K. Stone, D. Simh, D.E. Chandler and A.L. Bieber. Arizona State Univ., Tempe, AZ. 190 B168 Identification of a conserved candidate gene for the spermiogenesis defect in the mouse mutant quaking. D. Lorenzetti and M.J. Justice. Baylor Col. of Med., Houston, TX. 191 B169 Sperm nuclear basic proteins in Drosophila simulans undergoing Wolbachia-induced cytoplasmic incompatibility. H. Harris and H. Braig. Univ. of Wales, Bangor, United Kingdom. 192 B170 dpo is required in the niche cells to maintain germline stem cells in the Drosophila ovary. T. Xie, C. Doan, X. Song and A. Spradling. Stowers Inst. for Med. Res., Kansas City, MO and Carnegie Inst. of Washington, Baltimore, MD. 193 B171 Investigating egalitarian's function during Drosophila oogenesis. C. Navarro, J.Z. Morris and R. Lehmann. New York Univ. Med. Ctr., Skirball Inst., New York, NY. Neural Development 194 B172 Roles of Notch/Abl/Dab and Notch/Su(H) signaling pathways in Drosophila axon patterning. M. Le Gall, M. Gates, C. DeMattei and E. Giniger. Fred Hutchinson Cancer Res. Ctr., Seattle, WA. 195 B173 A targeted gain of function screen to identify genes involved in axon guidance in the Drosophila CNS. V.L. McGovern and M.A. Seeger. Ohio State Univ., Columbus, OH. 196 B174 Alternate isoforms of Lola regulate the coordinated expression of many networks of axon guidance molecules in Drosophila. S. Goeke, E.A. Greene and E. Giniger. Fred Hutchinson Cancer Res. Ctr., Seattle, WA. 197 B175 Getting from here to there: axon guidance in the periphery. J. Eberhart, M. Swartz, E.B. Pasquale, S.A. Koblar and C.E. Krull. Univ. of Missouri-Columbia, Columbia, MO, The Burnham Inst., La Jolla, CA and Univ. of Adelaide, Adelaide, Australia. 198 B176 Pioneer axon guidance errors in Pax6 mutants are rescued by whole mouse embryo electroporation. G.S. Mastick. Univ. of Nevada, Reno, NV. 199 B177 R-cadherin is a Pax6-regulated, growth-promoting cue for pioneer axons. G.L. Andrews and G.M. Mastick. Univ. of Nevada, Reno, NV. 200 B178 What is the role of the growth cone kinase Cdk5 in axon patterning? L. Connell-Crowley, D. Vo and E. Giniger. Fred Hutchinson Cancer Res. Ctr., Seattle, WA. 201 B179 Identifying C. elegans UNC-4 targets. S.E. Von Stetina and D.M. Miller III. Vanderbilt Univ., Nashville, TN. 202 B180 Lox6, a leech Dfd ortholog, may play a role in the patterning of the nervous systems. M.E. Mercado-Pimentel and G.O. Aisemberg. Lehman Col. of CUNY, Bronx, NY. 203 B181 Nerfin-1, a member of the conserved ein zn-finger subfamily, is required for proper cell fate specification in the developing Drosophila nervous system.. A. Kuzin, C. Stivers, T. Brody and W.F. Odenwald. NINDS, Bethesda, MD. 204 B182 A cDNA screen for Drosophila genes that are dynamically expressed during the generation of embryonic neural lineages. T. Brody, C. Stivers, A. Kuzin and W.F. Odenwald. NINDS, NIH, Bethesda, MD. 205 B183 Timing and competence of neural crest formation. M.L. Basch, M.A.J. Selleck and M. Bronner-Fraser. California Inst. of Technol., Pasadena, CA and Univ. of Southern California, Sch. of Med., Los Angeles, CA. 206 B184 Underlying mesoderm is not required for neural crest induction. J.W. Ragland and D.W. Raible. Univ. of Washington, Seattle, WA. 207 B185 Colgate b382 is required for the normal development of subsets of neural crest cells, primary neurons and the pectoral fin. R.M. Nambiar and P.D. Henion. Ohio State Univ., Columbus, OH. 208 B186 Survival and glial fate acquisition of neural crest cells are regulated by an interplay between the transcription factor Sox10 and extrinsic combinatorial signalling. L. Sommer, C. Paratore, D.E. Goerich, U. Suter and M. Wegner. Swiss Fed. Inst. of Technol., Zurich, Switzerland and Univ. of Erlangen-Nurnberg, Erlangen, Germany. 209 B187 Primary neuronal differentiation and orientated cell division in Xenopus. A.D. Chalmers, B. Strauss and N. Papalopulu. Univ. of Cambridge, Cambridge, UK. 210 B188 Regulation of neurogenesis by Hairy/Enhancer of split related proteins in Xenopus laevis. M. Solter, T. Hollemann, V. Gawantka, C. Niehrs, E.J. Bellefroid and T. Pieler. Univ. Gottingen, Gottingen, Germany, Deutsches Krebsforschungszentrum, Heidelberg, Germany and Univ. libre de Bruxelles, Gosselies, Belgium. 211 B189 A role for Dlx3 in neural plate border formation. J.M. Woda, J. Pastagia, K.B. Artinger and M. Mercola. Harvard Med. Sch., Boston, MA. 212 B190 Xrx1 controls neuronal differentiation in the anterior neural plate. M. Andreazzoli, G. Gestri and G. Barsacchi. Universita' di Pisa, Italy. 213 B191 Notch-mediated fate specification in the zebrafish neural tube. H. Park, A. Mehta, J. Richardson and B. Appel. Vanderbilt Univ., Nashville, TN. 214 B192 wimple, a mouse mutation that plays a role in Shh-dependent neural tube patterning. D. Huangfu and K.V. Anderson. Sloan-Kettering Inst. and Cornell Univ., New York, NY. 215 B193 Neurogenin1 functions as a switch between neuronal and non-neuronal fates in zebrafish lateral neural plate. R.A. Cornell and J.S. Eisen. Univ. of Oregon, Eugene, OR. 216 B194 G protein signaling in the developing zebrafish central nervous system. G.M. Kelly, B. Vanderbeld and M. Knowlton. Univ. of Western Ontario, London, Canada. 217 B195 A novel gene, axotrophin, is important in neural development. G.E. Lyons, M.A. Haendel, M. Epstein, M. Wagner and J. Johnson. Univ. of Wisconsin Med. Sch., Madison, WI. 218 B196 Effects of temperature on the gene expression of aromatase and estrogen receptors in the developing tilapia brain. C-L. Tsai. Natl. Sun Yat-sen Univ., Kaohsiung, Taiwan. 219 B197 Regulation of extracellular matrix-mediated contact inhibition of growth in the developing nervous system. L.S. Sherman, H. Morrison, F. Banine, J. Struve, G. Lepperdinger, T. Tuohy and C. Kuntz. Univ. of Cincinnati Col. of Med., Cincinnati, OH and Austrian Acad. of Sci., Inst. of Molec. Biol., Salzburg, Austria. 220 B198 Zfhep transcription factor may influence neural cell differentiation. D.S. Darling, G. Yen, R.T. Zoeller and R.P. Stearman. Univ. of Louisville, Louisville, KY and Univ. of Massachusetts, Amherst, MA. 221 B199 Cloning and expression of CRIM1 and its potential function in the development of the central nervous system. G.V. Kolle, A. Jansen, L. Wilkinson, M.H. Little and T. Yamada. Univ. of Queensland, St. Lucia, Australia. 222 B200 Bone morphogenetic protein control of Wnt ligands, secreted inhibitors and receptors during neural development. C.R. Chesnutt, A.M.C. Brown and L.A. Niswander. Cornell Univ. and Sloan Kettering Inst., New York, NY. 223 B201 BMP signaling in the mammalian dorsal neural tube. R.W. Stottmann, J. Wiedman, Y. Mishina and J.A. Klingensmith. Duke Univ. Med. Ctr., Durham, NC and NIEHS, Res. Triangle Park, NC. 224 PLEASE SEE WORKSHOP 4 Left-Right Asymmetry 225 B203 The zebrafish belladonna mutation specifically affects axon guidance in the ventral forebrain. J. Culverwell, M. Walkowicz and R. Karlstrom. Univ. of Massachusetts, Amherst, MA,. 226 B204 Retinoic acid synthesis for the developing telencephalon. U.C. Drager, D. Smith, E. Wagner, O. Koul and P. McCaffery. Harvard Med. Sch. and U. Mass. Med. Sch., Waltham MA. 227 B205 Isolation of a novel paired-like homeobox gene expressed in the midbrain of mouse embryos. A. Ohtoshi and R.R. Behringer. Univ. of Texas M.D. Anderson Cancer Ctr., Houston, TX. 228 B206 A novel function for EphB2 and EphB3 in maintaining cell shape in the developing ventral midbrain. A. Altick, G. Andrews, C. Cowan, N. Yokoyama, M. Henkemeyer, E. Nilsson and G. Mastick. Univ. of Nevada, Reno, NV. 229 B207 Relevance of TGF-β for the development of ventral midbrain dopaminergic neurons. U. Rauch, L. Farkas and K. Krieglstein. Univ. of Saarland, Homburg/Saar,, Germany. 230 B208 Shh and the isthmus regulate the development of early neurons in the midbrain. N. Fedtsova and E.E. Turner. UCSD, La Jolla, CA and VA Med. Ctr., San Diego, CA. 231 B209 Lmx1b functions in the zebrafish isthmic organizer. R.D. Riddle, P. O'Hara and A. Sebastian. Univ. of Pennsylvania Sch. of Med. Philadelphia, PA. 232 B210 Formation of the mesencephalic/metencephalic boundary. M. Zervas, S. Millet and A. Joyner. Skirball Inst. NYU Med. Ctr., New York, NY. 233 B211 Withdrawn 234 B212 Type I BMP receptors are expressed in cerebellar granular neurons and constitutive activation of the IA receptor induces cerebellar abnormalities. J.E. Ming, M. Elkan, K. Tang and J.A. Golden. Children's Hosp. of Philadelphia and Univ. of Pennsylvania Sch. of Med., Philadelphia, PA. 235 B213 Hedgehog signaling is required for zebrafish motoneuron development. K.E. Lewis and J.S. Eisen. Univ. of Oregon, Eugene OR. 236 B214 Function of zebrafish gli1 and gli2 in motor neuron development. A. Chandrasekhar. Univ. of Missouri, Columbia, MO. 237 B215 Hoxb1 coordinates specification of ventral motoneurons and dorsal interneurons at a specific anteroposterior level. G.O. Gaufo and M.R. Capecchi. Univ. of Utah, Salt Lake City, UT. 238 B216 Ectopic expression of Olig1 is deleterious to V3 interneuron development in the developing CNS. T. Sun, R. Lu, C. Stiles, Y. Echelard and D. Rowitch. Dana-Farber Cancer Inst. and Harvard Med. Sch., Boston, MA. 239 B217 GATA3 identifies a distinct ventral interneuron subtype in the developing spinal cord. A. Karunaratne, M. Hargrave and T. Yamada. Univ. of Queensland, Brisbane, Australia. 240 B218 Regulation and role of neural bHLH factors in spinal cord development. K. Gowan, A.W. Helms, P. Ebert, T. Hunsaker, T. Collisson, R. Odom and J.E. Johnson. Univ. of Texas Southwestern Med. Ctr., Dallas, TX. 241 B219 Hoxa5-overexpressing mice have spinal cord defects that impair sensory performance. K.E. Krieger, I.M. Sonea, M. Abbott and C.K. Tuggle. Iowa State Univ., Ames, IA. 242 B220 Sonic hedgehog signaling is required for proper development of zebrafish dorsal root ganglia. J.M. Ungos and D.W. Raible. Univ. of Washington, Seattle, WA. 243 B221 A genetic screen to identify zebrafish enteric nervous system mutants. I. Shepherd, T. Linbo and D. Raible. Univ. of Washington, Seattle, WA. 244 B222 Expression of chick calcium channel gamma subunit in differentiating neurons and myoblasts. A. Knecht, B. Kious and M. Bronner-Fraser. Caltech, Pasadena, CA. 245 B223 Neuronal cell differentiation in the developing mouse brain is influenced by peripheral axonal inputs from sensory and motor neurons. B. Kablar and M.A. Rudnicki. Dalhousie Univ., Halifax, Canada and Ottawa Hosp. Res. Inst., Ottawa, Canada. 246 B224 Multiple levels of auto-regulation on FGF signaling during mouse mid/hindbrain early patterning. A. Liu and A.L. Joyner. Skirball Inst., New York Univ. Sch. of Med., New York, NY. 247 B225 FGF signaling mediates an organizing activity in the zebrafish hindbrain. L. Maves and C.B. Kimmel. Univ. of Oregon, Eugene, OR. 248 B226 Role of nlz, a novel zinc finger protein, in the development of the zebrafish hindbrain. A.P. Runko and C.G. Sagerstrom. Univ. of Massachusetts Med. Ctr., Worcester, MA. 249 B227 Mosaic analysis of antennal lobe projection neurons suggests olfactory system connectivity is genetically predetermined. E.C. Marin, G.S.X.E. Jefferis, R.F. Stocker and L. Luo. Stanford Univ., Stanford, CA and Univ. of Fribourg, Perolles, Switzerland. 250 B228 Development of the avian olfactory placode. S. Bhattacharyya and M. Bronner-Fraser. California Inst. of Technol., Pasadena, CA. 251 B229 TGF-β modulates programmed cell death in the developing chick retina. N. Duenker, N. Schuster and K. Krieglstein. Univ. of Saarland, Homburg/Saar, Germany. 252 B230 The multipotency of retinal progenitor cells depends on Pax6 function. T. Marquardt, R. Ashery-Padan, N. Andrejewski and P. Gruss. Max-Planck Inst. of Biophys. Chem., Goettingen, Germany. 253 B231 Changes in the sensitivity to apoptosis during development of the retina are associated with Ref-1 expression. L.B. Chiarini, M.L. Leal-Ferreira, F.G. Freitas and R. Linden. UFRJ, Rio de Janeiro, Brazil. 254 B232 Characterization of retinal differentiation in zebrafish lacking the sonic hedgehog gene. D.M. Mallory, R.A. Frey and D.L. Stenkamp. Univ. of Idaho, Moscow, ID. 255 B233 Withdrawn 256 B234 IL-1β induces FGF production in the embryonic chick retina. E.I. Barragan, S.A. Avila, V. Chafrat and J. Cerdeira. Univ. Nacional del Comahue. Toschi and Arrayanes. Cipolletti Rio Negro, Argentina. 257 B235 Localization of components of the retinoic acid (RA) signaling system and effects of RA on photoreceptor patterning in embryonic zebrafish retina. S.N. Prabhudesai and D.L. Stenkamp. Univ. of Idaho, Moscow, ID. 258 B236 Taurine and the glycine receptor in vertebrate retinal development. T.L. Young and C.L. Cepko. Harvard Med. Sch., Boston, MA. 259 B237 Ath5 is required for retinal ganglion cell and optic nerve formation. N.L. Brown, S. Patel, J. Brzezinski and T. Glaser. Univ. of Michigan, Ann Arbor, MI and Northwestern Univ. Med. Sch, Chicago, IL 260 B238 Genetic analysis of neural stem cells in zebrafish retina. A. Wehman and H. Baier. Univ. of California, San Francisco, CA. |
| 3:30-3:45pm | Break |
| 4-5:30pm | Workshops |
| 1. Stem Cells | HUB Ballroom |
| Chair: | Janet Rossant |
| 261 | 4:00 | Janet Rossant
(Samuel Lunenfeld Research Institute, Canada) Stem cells from the mouse blastocyst |
| 262 | 4:20 | James Sherley
(Massachusetts Institute of Technology) Molecular determinants of asymmetric stem cell kinetics |
| 263 | 4:40 | Melissa
Carpenter (Geron Corporation) Lineage specific differentiation of human embryonic stem cells |
| 5:00 | Discussion |
| 2. Imaging and Cell Marking | Kane 120 |
| Chair: | Andras Nagy |
| 4:00 | Andras Nagy (Samuel Lunenfeld Research Institute, Canada) |
| 264 | 4:20 | Mary
Dickinson (Caltech) Analysis of somite development using a multi-photon, multispectral approach |
| 265 | 4:40 | Steven A. Farber
(Thomas Jefferson University) Visualizing lipid metabolism in live zebrafish |
| 5:00 | Discussion |
| 5:30-7pm | Dinner | McMahon |
| 7-9pm | Plenary
Session I Organ Building |
HUB Ballroom |
| Chair: | Cliff Tabin |
| 7:00 | Cliff
Tabin (Harvard Medical School) Patterning the chick embryo |
| 266 | 7:30 | Bruce
Morgan (Massachusetts General Hospital) Inductive signals that initiate feather bud development |
| 267 | 8:00 | Charles
Gasser (UC Davis) Genetic analysis of ovule morphogenesis |
| 268 | 8:30 | Didier
Stainier (UC San Francisco) Novel role for glycosaminoglycans in cell signaling events during heart valve initiation: cloning of the zebrafish jekyll |
| 9-11 pm | Poster Session I and Mixer | Upper Husky Den |
| Odd
number boards: Authors present at posters 1:30-3pm Even number boards: Authors present at posters 9-10:30pm |
|
Friday July 20th |
||
| 8am-5pm | Meeting Registration | Kane Lobby |
| 8-9am | Discussion on SDB's Moratorium on Cloning of Human Being | Kane 110 |
| Moderator: | Roger Pedersen (UC San Francisco) |
| 8-9am | Biotech/Imaging
Tutorials TBA |
| 8am-1pm | Set up for Poster Session II | Upper Husky Den |
| 9am-12:15pm | Concurrent symposia with 15 min coffee break around 10:30am |
| 4. Cell Interactions and Signaling Pathways 2 | Kane 120 |
| Chair: | Gail Martin |
| 269 | 9:00 | Gail
Martin (UC San Francisco) Genetic analysis of FGF gene function in limb development |
| 270 | 9:30 | Jeffery
Barrow (Harvard University) Wnt3 signaling in the limb ectoderm is required for the establishment of the AER |
| 271 | 9:45 | Randall
Moon (University of Washington) Multiple Wnt signaling pathways in vertebrates |
| 272 | 10:15 | Rebecca
Burdine (Skirball Institute) Nodal signaling regulates the laterality of asymmetries in the zebrafish |
| 10:30 | Break | |
| 273 | 10:45 | Jan
Christian (Oregon Health Sciences University) Calmodulin-dependent protein kinase IV mediated antagonism of BMP signaling regulates lineage commitment and survival of hematopoietic progenitors |
| 274 | 11:00 | Thomas
Kornberg (UC San Francisco) The role of cytonemes in patterning in Drosophila imaginal discs |
| 275 | 11:30 | Stephen
Cohen (European Molecular Biology Laboratory, Germany) Cell interactions and boundary formation in Drosophila wing development |
| 276 | 12:00 | Nancy
Huang (Harvard University) MEX-3 interacting proteins link cell polarity to asymmetric gene expression in C. elegans |
| 5. Patterning the Nervous System | Kane 210 |
| Chair: | Robb Krumlauf |
| 277 | 9:00 | Robb
Krumlauf (Stowers Institute for Medical Research) Patterning vertebrate head development |
| 278 | 9:30 | Andrea
Streit (King's College, U.K.) Early development of the otic placode |
| 279 | 9:45 | Cecilia
Moens (Fred Hutchinson Cancer Center) Hindbrain patterning in the zebrafish: Who helps the Hox genes? |
| 280 | 10:15 | John
Timmer (Sloan-Kettering Institute) BMPs regulate neural patterning via homeobox and bHLH |
| 10:30 | Break | |
| 281 | 10:45 | Yishi
Jin (UC Santa Cruz) Motor neuron axon guidance in C. elegans |
| 282 | 11:15 | Lisa
Goodrich (UC San Francisco) A gene trap screen for axon guidance receptors in mice |
| 11:30 | Chris
Kintner (Salk Institute) Regulation of neurogenesis |
|
| 283 | 12:00 | Nancy
Papalopulu (University of Cambridge, U.K.) Mechanisms for the spatial and temporal control of neurogenesis |
| 6. Regulation of Proliferation and Cell Growth | Kane 110 |
| Chair: | Bruce Edgar |
| 284 | 9:00 | Joan
Ruderman (Harvard Medical School) How does progesterone activate the quiescent frog oocyte? |
| 285 | 9:30 | Robert
Rea (University of York, U.K.) The co-ordination of cell division in the root meristem of Arabidopsis thaliana |
| 286 | 9:45 | Edward
Kipreos (University of Georgia) Regulation of C. elegans cell cycle by cullin/RING finger complexes |
| 287 | 10:15 | Vikram
Sudarsan (University of Cambridge, U.K.) Proneural genes pre-pattern cell proliferation during Drosophila renal tubule organogenesis |
| 10:30 | Break | |
| 10:45 | Bruce
Edgar (Fred Hutchinson Cancer Center) Coordinating growth and cell cycle progression in Drosophila |
|
| 288 | 11:15 | Molly
Duman-Scheel (University of Chicago) Hedgehog signaling promotes cell growth and proliferation by regulating expression of Rb/E2Fpathway components |
| 289 | 11:30 | David
Champlin (University of Southern Maine) Cell cycle by ecdysteroid and nitric oxide during insect metamorphosis |
| 290 | 11:45 | Hans
Clevers (University Medical Center Utrecht, The Netherlands) TCF factors, mediators of Wnt signaling |
| 12:30-1:30pm | Lunch | McMahon |
| 1:30-4pm | Poster Session II | Upper Husky Den |
|
Numbers in Italics
indicate the Program Abstract Number. Odd number boards: Authors
present at posters 1:30-3pm |
|
|
Development and Evolution 291 B1 Using RNAi to explore short-germband segmentation in Ocopeltus fasciatus. P.Z. Liu and T.C. Kaufman. Indiana Univ., Bloomington, IN, 292 B2 Potential for cross-interference with RNAi. J. Norman, E. Bishop and M.K. Montgomery. Macalester Col., St. Paul, MN. 293 B3 Tools for nematode evodevo studies. G. Padilla, S. Goetz and M.K. Montgomery. Macalester Col., St. Paul, MN. 294 B4 Deep homologies among members of the Hox11 gene family. C.C. Coutinho, R.N. Fonseca and R. Borojevic. UFRJ, Rio de Janeiro, Brazil. 295 B5 The expression of centipede Hox genes and the evolution of the arthropod body plan. C.L. Hughes and T.C. Kaufman. Indiana Univ., Bloomington, IN. 296 B6 Evolution of the gnathostome body plan. M.J. Cohn. Univ. of Reading, Whiteknights, UK. 297 B7 How to make a pufferfish: Hox clusters and early development in Fugu rubripes. A. Amores, T. Suzuki, C.T. Amemiya and J.H. Postlethwait. Univ. of Oregon, Eugene, OR, Mie NRIA, Nansei, Mie, Japan and Boston Univ. Sch. of Med., Boston, MA. 298 B8 Distinct functions for the Hox paralogue group 1 genes in neuronal patterning of the zebrafish hindbrain. J.M. McClintock and V.E. Prince. Univ. of Chicago, Chicago, IL. 299 B9 The role of Hoxc8 early enhancer in mouse development. H. Juan and F. Ruddle. Yale Univ., New Haven, CT. 300 B10 The role of NOS in ascidian development. A.P. Jackson and B.J. Swalla. Univ. of Washington, Seattle, WA. 301 B11 Novel early development of the indirect developing sea urchin Echinometra esculenta (Euchinoidea, Echinometridae). J.B. Morrill. New Col. of USF, Sarasota, FL. 302 B12 A gap gene ortholog in polychaetes. R. Savage, A. Werbrock, D. Meiklejohn, A. Sainz and J. Iwasa. Williams Col., Williamstown, MA. 303 B13 Mechanisms of segment formation in polychaete annelids. E.C. Seaver, D.A. Paulson, S.Q. Irvine, S.D. Hill and M.Q. Martindale. Univ. of Hawaii, Honolulu, HI, Yale Univ., New Haven, CT and Michigan State Univ. 304 B14 A hedgehog homolog regulates gut formation in leech (Helobdella). D. Kang, F.Z. Huang, D. Li, M. Shankand, W. Gaffield and D.A. Weisblat. Univ. of California, Berkeley, CA, Stanford Univ., Stanford, CA, Univ. of Texas, Austin, TX and ARS, USDA, Albany, CA. 305 B15 Supercompact genome in the protochordate Oikopleura dioica. H.C. Seo, R.E. Edvardsen, M.F. Jensen, E. Spriet, E.M. Thompson and D. Chourrout. Sars Intl. Ctr. for Molec. Marine Biol., Bergen, Norway. 306 B16 Proliferation is linked to larval caste fate in the polyembryonic wasp Copidosoma floridanum. L.S. Corley and M.R. Strand. Univ. of Wisconsin-Madison, Madison WI. 307 B17 Targeted disruption of Dmrt2, a putative transcription factor, results in abnormal rib patterning and perinatal death. K-W. Seo, B.S. Kim, H. Kokubo and R.L. Johnson. Univ. of Texas MD Anderson Cancer Center, Houston, TX. 308 B18 Dpp expression during biphasic development of the legs in Manduca sexta. K. Tanaka and J.W. Truman. Univ. of Washington, Seattle, WA. 309 B19 When is an eyespot not an eyespot? J.M. Marcus. Duke Univ., Durham, NC. 310 B20 Analysis of cxcr4 gene in zebrafish embryogenesis. S.W. Chong, A. Emelyanov, Z. Gong and V. Korzh. Natl. Univ. of Singapore, Singapore. 311 B21 A novel mutation screen in zebrafish using temperature mediated heteroduplex analysis can detect single base changes in ENU mutated chormosomes. J.J. Willoughby, B.W. Draper and J.H. Postlethwait. Univ. of Oregon, Eugene, OR. 312 B22 p63, a homologue of tumor suppressor p53, marks the epithelial stem cell identity in zebrafish. H. Lee, F. McKeon and D. Kimelman. Univ. of Washington, Seattle, WA and Harvard Med. Sch., Boston, MA. 313 B23 Variation in the mechanisms driving gastrulation in urodeles and anurans. D.R. Shook and R. Keller. Univ. of Virginia, Charlottesville, VA. 314 B24 Evidence for the co-evolution of neural crest and cranial placodes. S.C. Smith and A.C. Graveson. 315 B25 On the role of Sox9 in cartilage formation. B.F. Eames, P.T. Sharpe and J.A. Helms. Univ. of California, San Francisco, CA and Guy's Hosp., London, UK. 316 B26 Gene expression in the oral and pharyngeal dentition of two species of teleost fishes. D.W. Stock and K.M. Weiss. Univ. of Colorado, Boulder, CO and Pennsylvania State Univ., University Park, PA. 317 B27 Subfunctionalization of duplicate mitf genes in zebrafish. J.A. Lister, J. Close and D.W. Raible. Univ. of Washington, Seattle, WA. 318 B28 Sonic hedgehog controls the eyeless phenotype in cavefish. Y. Yamamoto, D.W. Stock and W.R. Jeffery. Univ. of Maryland, College Park, MD and Univ. of Colorado, Boulder, CO. 319 B29 The importance of lens differentiation in directing eye development of the teleost Astyanax mexicanus. A.G. Strickler and W.R. Jeffery. Univ. of Maryland, College Park, MD. 320 B30 Experimental analysis of the "branching and segmentation" model of tetrapod limb development. R.D. Dahn and J.F. Fallon. Univ. of Wisconsin, Madison, WI. 321 B31 Comparative limb morphogenesis in mice and bats. C.J. Cretekos, J.J. Rasweiler IV and R.R. Behringer. Univ. of Texas M.D. Anderson Cancer Ctr., Houston, TX. 322 B32 Limb development in the short-tailed fruit bat Carollia perspicillata. S.D. Weatherbee, C.J. Cretekos, R. Behringer, J.J. Rasweiler IV and L.A. Niswander. Mem. Sloan Kettering Cancer Ctr., New York, NY and M.D. Anderson Cancer Ctr., Houston, TX. 323 B33 Evolution of POU/homeodomains in basal metazoa: implications for the evolution of sensory systems and the pituitary. D.K. Jacobs and R.D. Gates. UCLA, Los Angeles, CA. 324 B34 Seamonster development: comparative embryology and evolution of the Bilateria. E. Edsinger-Gonzales, M. van der Zee, W.J.A.G. Dictus and J.A.M. van den Biggelaar. Smithsonian Marine Sta., Fort Pierce, FL and Univ. of Utrecht, Utrecht, The Netherlands. 325 B35 Further characterization of dorsal- and snail-class genes in the leech Helobdella robusta. P. Xiao, D. Kang and D.A. Weisblat. Univ. of California, Berkeley, CA and Stanford Univ., Stanford, CA. 326 B36 The evolution of vertebrate snail genes.. J.A. Langeland and R.A. Rahimi. Kalamazoo Col., Kalamazoo, MI. 327 B37 Juvenile hormone induces a heterochronic shift in cuticle formation and alters growth during embryonic development of Orthoptera. D.F. Erezyilmaz, L.M. Riddiford and J.W. Truman. Univ. of Washington, Seattle, WA. 328 B38 Metamorphosis. C. Bishop and J. Hodin. Simon Fraser Univ., Burnaby, Canada and Friday Harbor Labs., Friday Harbor, WA. Education 329 B39 Evo-Devo 2001: a teaching and research odyssey. A. Candelaria, I. Chevere, M. Colon, E. Geral, J.L. Gonzalez, J.M. Mojica, A. Puig, X. Ramos, N.L. Rivera, K. Salas, I. Soto, A. Tobler and E. Rosa-Molinar. Univ. of Puerto Rico-Rio Piedras, San Juan, PR. 330 B40 Integration of inquiry-based learning in developmental biology. D.K. Darnell. Lake Forest Col., Lake Forest, IL. Developmental Biology and Medicine 331 B41 Effect of tumor necrosis factor - α on preimplantation stage embryo development. P.G.L. Lalit Kumar, J. Sengupta and D. Ghosh. All India Inst. of Med. Sci., New Delhi, India. 332 B42 The genes encoding the mammalian hatching enzymes. D. Rancourt, S. Liu, S. Rancourt and C. O'Sullivan. Univ. of Calgary, Calgary, Canada. 333 B43 PLP-Cg, a novel member of the prolactin-like protein-C subfamily, produces two alternatively spliced forms. I.-T. Hwang and J.-Y. Chun. Ewha Womans Univ., Seoul, Korea. 334 B44 Defects in TGF beta signaling by Smad 4 and ELF spectrins are associated with gastric carcinogenesis. Y. Tang, C. Fox, S. Danovitch, T. Fleury, B. Mishra, A. Sidawy, C. Deng and L. Mishra. DVAMC, Washington, DC and Fels Inst., Temple Univ., Philadelphia, PA, George Washington Univ, and Sibley Hosps., Washington, DC, NHGRI and NIDDK, NIH, Bethesda, MD, VA and Walter Reed Army Med. Ctrs., Washington, DC. 335 B45 Functional analysis of a dominant-negative human PAX6 mutation in Drosophila. T. Glaser, B. Gordesky-Gold, N. Bonini, T.V. Orenic, A. Sugar and N. Brown. Univ. of Michigan, Ann Arbor, MI, Univ. of Pennsylvania, Philadelphia, PA, Univ. of Illinois, Chicago, IL and Northwestern Univ. Med. Sch., Chicago, IL. 336 B46 Why do small eye (Pax6+/-) mice have small eyes?. J.M. Collinson, J.C. Quinn, M.A. Buchanan, M.H. Kaufman, S.E. Wedden, R.E. Hill and J.D. West. Univ. of Edinburgh, Edinburgh, UK and MRC Human Genet. Unit, Edinburgh, UK. 337 B47 Regulation of left-right asymmetry by thresholds of pitx2c activity.. C. Liu, W. Liu, M.-F. Lu, N.A. Brown and J.F. Martin. Texas A&M Syst. Hlth. Sci. Ctr., Houston, TX and St. Georgeis Hosp. Med. Sch., Univ. of London, London, UK. 338 B48 Analysis of Tbx1 function in Xenopus laevis. P. Ataliotis, B. Latinkic, T.J. Mohun and P.J. Scambler. Inst. of Child Hlth., London, UK and Natl. Inst. for Med. Res., London, UK. 339 B49 Ethanol teratogenesis in the zebrafish, Danio rerio. P.Z. Myers, M. Larson and M. Hartwell. Univ. of Minnesota, Morris, Morris, MN. 340 B50 Using collagen microcarriers to deliver cells for bone tissue engineering. J.S. Doctor, S. Salvaterra, D. Vitrant, K. Azari, M.A. Ihnat, J.O. Hollinger and P. Campbell. Carnegie Mellon Univ., Pittsburgh, PA, Duquesne Univ., Pittsburgh, PA and Univ. of Pittsburgh Med. Ctr., Pittsburgh, PA. 341 B51 Acetabularia acetabulum: a novel model for arsenic toxicity. L.S. Townsend, N. Dejbod, W. Cullen and D. Mandoli. Univ. of Washington, Seattle, WA and Univ. of British Columbia, Vancouver, Canada. Cell Proliferation 342 B52 Oxygen deprivation causes reversible-developmental arrest in the S and G2 phases of the cell cycle in zebrafish. P.A. Padilla and M.B. Roth. Fred Hutchinson Cancer Res. Ctr., Seattle, WA. 343 B53 Multiple Wee1-like kinases regulate the cell cycle during Xenopus development. W.F. Leise and P.R. Mueller. Univ. of Chicago, Chicago, IL. 344 B54 Regulation and degradation of cyclin E in the early embryonic cell cycle. B. Boyle, M. Slevin, Y. Audic and R.S. Hartley. Univ. of Iowa, Iowa City, IA. 345 B55 XChk1 as a molecular switch between cell cycle arrest and apoptosis in Xenopus embryos. J.C. Sible, A.B. Carter, M. Petrus and B. Johnson. Virginia Tech., Blacksburg, VA. 346 B56 Flk-1 inhibition modulates the Flt-1 mutant phenotype during blood vessel formation. D.M. Roberts, J.H. Johnson, M.P. Rosenberg and V.L. Bautch. Univ. of North Carolina at Chapel Hill, Chapel Hill, NC and Glaxo SmithKline Inc., Res. Triangle Park, NC. 347 B57 Flt-1 (VEGFR-1) negatively regulates blood vessel formation by modulating endothelial cell division. J.B. Kearney, C.A. Ambler, K.A. Monaco, N. Johnson, R.G. Rapoport and V.L. Bautch. Univ. of North Carolina Chapel Hill, Chapel Hill, NC. 348 B58 Identifying modifiers of cyclin D/CDK4-directed overgrowth. L.J. Saucedo, S.A. Datar and B.A. Edgar. Fred Hutchinson Cancer Res. Ctr., Seattle, WA. 349 B59 Regulation of cell growth and adhesion by Drosophila Ras1. D.A. Prober and B.A. Edgar. Fred Hutchinson Cancer Res. Ctr., Seattle, WA. 350 B60 Conditional expression of Axin by the tetracycline-dependent system in transgenic mice: the role of Axin in regulating cell growth, differentiation and death during the postnatal development of mice. W. Hsu and F. Costantini. Col. of Physicians and Surgeons, Columbia Univ., New York, NY. 351 B61 Expression of thymosin beta 4 in different proliferation of murine bone marrow endothelial cells. J. Huang, W. Huang and Q. Wang. Central South Univ., Changsha, China. 352 B62 A conserved leucine in RbAp46, a WT1 target, is required for growth suppression. J.R. McCarty and M.I. Rauchman. Washington Univ. Sch. of Med., St. Louis, MO. Cell Lineage 353 B63 Is there a role for asymmetric division in Arabidopsis development? D.C. Bergmann and C.R. Somerville. Carnegie Inst. of Washington, Stanford, CA. 354 B64 Developmental timing in C. elegans. H. Gardner, M. Jeon and A. Rougvie. Univ. of Minnesota, St. Paul, MN. 355 B65 Cardiac neural crest in zebrafish. M. Sato and H.J. Yost. Univ. of Utah, Salt Lake City, UT. 356 B66 Characterization of the zebrafish hematopoietic system by flow cytometry. D. Traver, N. Kotsopoulou, R. Mulligan and L. Zon. HHMI and Children's Hosp., Boston, MA. 357 B67 Primitive and definitive blood share a common origin in early Xenopus: a comparison of lineage labeling techniques. M.C. Lane and M.D. Sheets. Univ. of Wisconsin, Sch. of Med., Madison, WI. 358 B68 Cranial neuroectoderm produces vascular smooth muscle cells and pericytes in brain. H. Kurz, J. Korn and B. Christ. Univ. of Freiburg, Freiburg, Germany. 359 B69 Conditionally immortalized cell line of metanephric mesenchyme. Z.B. Levashova, S.Y. Plisov and A.O. Perantoni. Natl. Cancer Inst., Frederick, MD. 360 B70 Conditional genetic ablation using puΔtk and Cre/loxP technology. Y.T. Chen and A. Bradley. Baylor Col. of Med., Houston, TX and The Sanger Ctr., Cambridge, UK. Signalling Pathways 361 B71 The COP9 signalosome regulates multiple pleiotropic pathways in Drosophila melanogaster. E. Oron, O. Harari-Steinberg, S. Rencus, N. Egoz, D. Segal and D.A. Chamovitz. Tel Aviv Univ., Tel Aviv, Israel. 362 B72 Localization of flamingo in the Drosophila eye disc and its prospective role in eye development. G. Das and M. Mlodzik. Mount Sinai Sch. of Med., New York, NY. 363 B73 Germinal vesicle breakdown in ascidian oocytes is controlled by kinases and phosphatases. C.C. Lambert. Univ. of Washington, Friday Harbor, WA. 364 B74 The role of NO/cGMP and HSP90 in regulating metamorphosis of the sea urchin Lytechinus pictus. C.D. Bishop and B.P. Brandhorst. Simon Fraser Univ., Burnaby, Canada. 365 B75 PKC and embryonic organization in Ilyanassa obsoleta. J. Wandelt and L. Nagy. Univ. of Arizona, Tucson, AZ. 366 B76 GPI-linked and transmembrane ephrins are localized in distinct membrane microdomains and regulate different biological processes. A. Davy and S.M. Robbins. Univ. of Calgary, Calgary, Canada. 367 B77 Relieving TCF-mediated repression during zebrafish embryogenesis-a role for nemo-like kinase? C.J. Thorpe and R.T. Moon. Univ. of Washington, Seattle, WA. 368 B78 HeyL: a new mammalian mediator of Notch signaling. C. Steidl, K.P. Knobeloch, C. Leimeister, M. Maier and M. Gessler. Univ. of Wuerzburg, Germany and Res. Inst. for Molec. Pharmacol., Berlin, Germany. 369 B79 Spatial and temporal patterns of RTK signaling in the developing mouse embryo. L. Corson, M. Ema, V. Lai and J. Rossant. Samuel Lunenfeld Res. Inst., Mount Sinai Hosp., Toronto, Canada. 370 B80 Targeted genomic disruption of Mek2 reveals its dispensability for mmouse growth and development. J. Charron, L. Belanger, M. Tremblay, B. Brott and R. Erikson. Univ. of Laval, L'Hotel-Dieu de Quebec, Quebec, Canada and Harvard Univ., Cambridge, MA. C 371 B81 The nuclear translocation of phosphorylated MAP kinase is a developmentally regulated process in the developing Drosophila eye. J.P. Kumar and K. Moses. Emory Univ. Sch. of Med., Atlanta, GA. 372 B82 A misexpression screen to identify novel regulators of growth and proliferation in Drosophila. R.E. Foulger, D.C.I. Goberdhan and C. Wilson. Univ. of Kent, Canterbury, UK. 373 B83 The functions of the proteoglycan syndecan in Drosophila development. T.R. Heslip, K.H. Soanes, O. Marcu and J.L. Marsh. Univ. of Calgary, Calgary, Canada and Univ. of California-Irvine, Irvine, CA. 374 B84 Are Wnts ligands for planar polarity signaling? C.Y. Logan, C-H. Wu, A. Aurora, K. Cadigan and R. Nusse. Stanford Univ., Stanford, CA. 375 B85 GSK-3 interactions with GBP and axin in early Xenopus development. D.M. Ferkey and D. Kimelman. Univ. of Washington, Seattle, WA. 376 B86 Difference in dependency on XTcf-3 function accounts for the dramatic change of response to Wnt signalling at mid-blastula transition in Xenopus. S. Hoppler, F.S. Hamilton and G.N. Wheeler. Univ. of Dundee, Scotland, UK. 377 B87 Frizzled-dependent apoptosis in Xenopus embryos. K. Itoh, M. Lisovsky and S.Y. Sokol. Harvard Med. Sch. and Beth Israel Deaconess Med. Ctr., Boston, MA. 378 B88 PP2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus. J.M. Seeling, X. Li, H.J. Yost and D.M. Virshup. Univ. of Utah, Salt Lake City, UT. 379 B89 Dpr, a Wnt signaling antagonist, binds to the Dsh PDZ domain and colocalizes with Dsh. B.N.R. Cheyette, J.R. Miller, N. Khlebtsova, K-I. Takemaru, L.C. Sheldahl, J.S. Waxman, T. Earnest and R.T. Moon. Univ. of Washington Sch. of Med., Seattle, WA and Lawrence Berkeley Natl. Lab., Berkeley, CA. 380 B90 Withdrawn 381 B91 Derepression of nodal signaling by FoxD3 is essential for Xenopus mesoderm formation. M.J. Engleka, J. Lefebvre, S. Yaklichkin, A. Steiner, E.J. Craig, P.A. Labosky and D.S. Kessler. Univ. of Pennsylvania Sch. of Med., Philadelphia, PA. 382 B92 Amnionless, an essential gene for mouse gastrulation, encodes a visceral endoderm-specific protein with an extracellular cysteine-rich domain. S. Manning, S. Kalantry, R. Rivi, F. Lupu and E. Lacy. Sloan-Kettering Inst., New York, NY. 383 B93 The zebrafish umleitung locus affects hh signaling and forebrain patterning. O. Tyurina and R. Karlstrom. Univ. of Massachusetts, Amherst, MA. 384 B94 Sonic hedgehog signaling is required for formation of the dorsal aorta. A.M. Vogel, N.D. Lawson and B.M. Weinstein. NICHD, NIH, Bethesda, MD. 385 B95 Ptc1 and Ptc2 transcripts provide distinct readouts of hedgehog signaling activity during chick embryogenesis. R.V. Pearse, K.J. Vogan and C.J. Tabin. Harvard Med. Sch., Boston, MA. 386 B96 A screen to identify Indian hedgehog target genes involved in bone formation. M. Wenzel, S. Schneider, W. Gaffield and A. Vortkamp. Max-Planck-Inst. for Molec. Genet., Berlin, Germany and Western Reg. Res. Ctr., ARS, USDA, Albany CA. 387 B97 Interaction of Ihh, BMP and FGF signaling during chondrocyte differentiation. E. Minina, C. Kreschel, M. Wenzel and A. Vortkamp. Max-Planck-Inst. for Molec. Genet., Berlin, Germany. 388 B98 A screen to identify new genes involved in the development of skeletal elements. K. Lintermann, S. Schneider and A. Vortkamp. Max-Planck-Institut for Molec. Genet., Berlin, Germany. 389 B99 Tissue specific knockout shows BMP signaling is required for articular cartilage maintenance in vertebrate joints. R.B. Rountree, M. Schoor, M. Marks, Y. Mishina and D. Kingsley. Stanford Univ., Stanford, CA and NIEHS/NIH, Res. Triangle Park, NC. 390 B100 Endogenous patterns of BMP signaling during chicken development. P. de Santa Barbara, S. Faure, M. Whitman and D.J. Roberts. Massachusetts Gen. Hosp., Harvard Med. Sch., Boston, MA. 391 B101 A novel cleavage site within proBMP-4 regulates the bioactivity and signaling range of the BMP-4 ligand. Y. Cui, L. Berg, R. Hackenmiller, T. Nakayama, F. Jean, G. Thomas and J. Christian. Oregon Hlth. Sci. Univ., Portland, OR. 392 B102 Calmodulin-dependent protein kinase IV mediated antagonism of BMP signaling regulates lineage commitment and survival of hematopoietic progenitors. G.A. Wayman, M.J. Walters, J.C. Notis, R.H. Goodman, T.R. Soderling, and J.L. Christian. Vollum Inst. and Oregon Hlth. Sci. Univ., Portland OR. 393 B103 Local and long-range requirements for the BMP homolog glass bottom boat in the Drosophila wing disk reveal novel mechanisms for signaling by multiple BMPs. R.P. Ray and K.A. Wharton. Brown Univ., Providence, RI. 394 B104 Control of cell growth and differentiation by TGFβ-related signaling in C. elegans. C. Savage-Dunn, R. Tokarz and L. Yu. CUNY, Flushing, NY. 395 B105 SNT-1 is a component of the FGF pathway that functions during Xenopus development. J. Hama, M. Goldfarb and D.C. Weinstein. Mount Sinai Sch. of Med., New York, NY. 396 B106 Regulation of fgf-19: signaling hierarchies controlling otic development. R.K. Ladher, P.H. Francis-West and G.C. Schoenwolf. Univ. of Utah Sch. of Med., Salt Lake City, UT. 397 B107 Insulin-like growth factors promote somite myogenesis in the avian embryo. J.C. Kiefer, A. Pirskanen and S.D. Hauschka. Univ. of Washington, Seattle, WA. 398 B108 The mouse gastrulation mutant lazy mesoderm: a novel component of the FGF pathway? M.J. García-García and K.V. Anderson. Mem. Sloan-Kettering Inst., New York, NY. 399 B109 A quantitative relationship exists between the number of functional PDGFRβ signaling pathways and the formation of pericytes. M.D. Tallquist and P. Soriano. Fred Hutchinson Cancer Res. Ctr., Seattle, WA. 400 B110 Withdrawn 401 B111 Structure - function studies of caveolae in Smith Lemli Opitz disease. J.V. Sutton and R.K. Keller. Col. of Med., Univ. of South Florida, Tampa, FL. Gene Expression 402 B112 Gene expression database for the laboratory mouse. D.A. Begley, J.T. Eppig, T. Hayamizu, D.P. Hill, J. Kadin, I.J. McCright, J. Richardson, C. Smith and M. Ringwald. The Jackson Lab., Bar Harbor, ME. 403 B113 A computational approach to the dissection of genetic regulatory networks involved in metazoan development. M.S. Halfon, Y. Grad, G. Church and A.M. Michelson. Brigham & Women's Hosp. and Harvard Med. Sch., Boston, MA. 404 B114 A functional genomic approach to neural crest gene discovery and analysis using a combination of expression profiling and in vitro expression. D. Larson, S. Loftus, D. Watkins-Chow, L. Baxter, A. Antonellis, K. Joyce Dunn and W. Pavan. NIH, Bethesda, MD. 405 B115 Microarrays in neural stem cell systems. F.C. Mansergh, S.E. Minnema, M.A. Wride, J.M. Somani, J.E. Hance, S. Weiss and D.E. Rancourt. Univ. of Calgary, Calgary, Canada. 406 B116 Expression profile analysis to dissect genetic mechanisms of neural crest development. S.K. Loftus, L.L. Baxter, D.M. Larson and W.J. Pavan. Natl. Institutes of Hlth., Bethesda, MD. 407 B117 Combinatorial regulation of LIM homeodomain transcription factors by LIM domain binding proteins. H.P. Ostendorff, M. Peters, R.I. Peirano and I. Bach. Univ. of Hamburg, Hamburg, Germany. 408 B118 Rescue of the shootmeristemless (stm) mutant phenotype by expression of STM mRNA in a subset of its normal domain: implications for nonautonomous action of the STM transcription factor in Arabidopsis thaliana. A.G. Fernandez, J.A. Long, R.E. Joy and M.K. Barton. Univ. of Wisconsin-Madison, Madison, WI. 409 B119 Regulation of OSL, a LFY homologue, during rice panicle and spikelet development. K. Prasad and U. Vijayraghavan. Indian Inst. of Sci., Bangalore, India. 410 B120 Determination of intraplant ploidy variation in Spathoglottis plicata, a tropical orchid, by flow cytometry. M-C. Yang and C.S. Loh. Natl. Univ. of Singapore, Singapore. 411 B121 A homolog of mammalian hypoxia-inducible factor-1α is required for adaptation to low oxygen in C. elegans. H. Jiang, R. Guo and J.A. Powell-Coffman. Iowa State Univ., Ames, IA. 412 B122 Broad complex: a pupal-specific transcription factor that mediates the "status quo" effects of juvenile hormone. X. Zhou and L.M. Riddiford. Univ. of Washington, Seattle, WA. 413 B123 mRNA 5′-leader trans-splicing in the chordates. T.H. Meedel, A.E. Vandenberghe, K.E.M. Hastings. Rhode Island Col., Providence, RI, McGill Univ., Montreal, Canada. 414 B124 Positional cloning of the gene disrupted in the zebrafish notochord mutant, bashful. S.M. Pollard, M.J. Parsons and D.L. Stemple. Natl. Inst. for Med. Res., London, UK. 415 B125 Investigating the regulatory elements controlling Sox10 expression in zebrafish. J.R. Dutton, T. Carney, A.W. Ward and R.N. Kelsh. Univ. of Bath, Bath, UK. 416 B126 Characterization of the onset timing and expression pattern of Mab21 genes in zebrafish. K.L. Chow and Y.M. Wong. Hong Kong Univ. of Sci. and Technol., Hong Kong. 417 B127 Zebrafish novel immune-type receptors are putative orthologs of the genes encoded by the mammalian lymphocyte receptor complex. J.A. Yoder, S. Wei, J.Y. Djeu and G.W. Litman. Children's Res. Inst., Univ. of South Florida and All Children's Hosp., St. Petersburg, FL and H. Lee Moffitt Cancer Ctr. and Res. Inst., Tampa, FL. 418 B128 Use of transgenic Xenopus embryos to analyze the Xath5 promoter. D.A. Hutcheson and M.L. Vetter. Univ. of Utah Sch. of Med., Salt Lake City, UT. 419 B129 Transgenic technology and targeted gene expression in Xenopus laevis using the GAL4/UAS system. A. Rolo, P. Skoglund and R. Keller. Univ. of Virginia, Charlottesville, VA. 420 B130 Translational regulation of cyclin A1 during early embryogenesis. Y. Audic, M. Garbrecht, B. Boyle and R.S. Hartley. Univ. of Iowa, Iowa City, IA. 421 B131 Functional studies of the Xenopus polycomb-group proteins Xeed and Xez. C. Showell, J.B. Rafferty and V.T. Cunliffe. Univ. of Sheffield, Sheffield, UK. 422 B132 Regulated translation of BMP signaling pathway mRNAs during frog embryogenesis. B.R. Fritz and M.D. Sheets. Univ. of Wisconsin, Madison, WI. 423 B133 Regulation of ectodermal patterning in Xenopus by differential sensitivity of Dlx homeodomain genes to BMP signal attenuation. T. Luo, M. Matsuo-Takasaki and T.D. Sargent. NICHD, Natl. Inst. of Hlth., Bethesda, MD. 424 B134 Regulation of sox3 expression in Xenopus laevis. E. Silva Casey and R. Harland. Univ. of California, Berkeley, CA. 425 B135 Characterization and expression of the mRNAs encoding the tadpole and adult globins during spontaneous and thyroid hormone-induced amphibian metamorphosis. R. Gowing, B.G. Atkinson. Univ. of Western Ontario, London, Canada. 426 B136 Muscle-specific, cytosolic creatine kinase mRNA levels are elevated in muscle of thyroid hormone-induced metamorphosing amphibian tadpoles. L.F. Petersen and B.G. Atkinson. Univ. of Western Ontario, London, Canada. 427 B137 Characterization of an amphibian alpha smooth muscle actin gene and its expression in the heart and developing limb of metamorphosing tadpoles. L. Zheng and B.G. Atkinson. Univ. of Western Ontario, London, Canada. 428 B138 Transgenic studies into cardiac troponin I gene regulation during the postembryonic development (metamorphosis) of the amphibian tadpole. A.S. Warkman and B.G. Atkinson. Univ. of Western Ontario, London, Canada. 429 B139 Analysis of AER enhancer elements in the chicken Msx2 gene. H.C. Cheng, Z.Z. Pan, C.K.L. Wang and W.B. Upholt. Univ. of Connecticut Hlth. Ctr., Farmington, CT, Fox Chase Cancer Ctr., Philadelphia, PA and Academia Sinica, Taiwan. 430 B140 Isolation of a novel member of the spalt family of zinc finger genes in chickens. M. Barembaum and M. Bronner-Fraser. California Inst. of Technol., Pasadena, CA. 431 B141 Regionally-restricted expression pattern of id helix-loop-helix genes during early avian embryogenesis. Y. Kee and M. Bronner-Fraser. California Inst. of Technol., Pasadena, CA. 432 B142 Establishment of distinct signaling centers in the avian frontonasal process. R.S. Marcucio, M. Tong and J.A. Helms. Univ. of California, San Francisco, CA. 433 B143 Hox gene expression within the embryonic skin is dynamic. A.I. Reid and S. Gaunt. Babraham Inst., Cambridge, UK. 434 B144 Wnt signaling in avian kidney development. T.J. Mauch, R. Ladher, P. Garcia-Villalba, D.E. Smith and G.C. Schoenwolf. Univ. of Utah Sch. of Med., Salt Lake City, UT. 435 B145 Colinear expression of the mouse HoxB cluster: potential role of chromatin remodeling. J.E. Basford and S. Bradshaw. Univ. of Cincinnati, Cincinnati, OH. 436 B146 Novel ring finger proteins PRAJA-1 and AVP-36 play distinct roles in ubiquitination and protein trafficking in epithelial cell formation. C. Fox, Y. Tang, A. Subramanian, C. Banumathy, S. Radhakrishnan, B. Mishra, A. Sidawy and L. Mishra. DVAMC, Washington, DC and Fels Cancer Inst., Temple Univ., Philadelphia, PA and VA and Walter Reed Army Med. Ctrs., Washington, DC. 437 B147 Cloning and expression analysis of OSR2, a new mouse gene related to Drosophila odd-skipped. Y. Lan, E.S. Cho, P.D. Kingsley and R.J. Jiang. Univ. of Rochester Sch. of Med. and Dent., Rochester, NY. 438 B148 Identification of potential cis-acting regulatory elements in the mouse Fibroblast growth factor 10 locus. J.C. Grindley, L. O'Rear, Z. Liu, D. Perkins, S. Bellusci and M.G. Rush. Vanderbilt Univ., Nashville, TN. 439 B149 Transcriptional effects of altering protein kinase C distribution in 4-cell stage mouse embryos. H. Dehghani and A. Hahnel. Univ. of Guelph, Guelph, Canada. 440 B150 Analysis of genes differentially expressed between morula and blastocyst. T.S. Tanaka and M.S.H. Ko. Natl. Inst. on Aging/NIH, Baltimore, MD. 441 B151 Molecular characterization of the Twis allele of the mouse Brachyury gene. S.N. Hancock and V.E. Papaioannou. Columbia Univ., New York, NY. 442 B152 Gene expression during somitogenesis. L.A. Buttitta, T.S. Tanaka, M.S. Ko and C.M. Fan. Carnegie Inst. of Washington, Baltimore, MD and Natl. Inst. on Aging, NIH, Bethesda, MD. 443 B153 A novel mouse zinc finger isolated from an embryonic stem cell neural differentiation paradigm. M.A. Wride, F.C. Mansergh, R. Everitt, J.E. Hance and D.E. Rancourt. Univ. of Calgary, Calgary, Canada. 444 B154 Isolation of putative AP-2α target genes from craniofacial mesenchyme. D.K. Nelson and T. Williams. Yale Univ., New Haven, CT and Univ. of Colorado Hlth. Sci. Ctr., Denver, CO. 445 B155 Antagonistic regulation of Dlx2 expression by PITX2 and Msx2: implications for tooth development. P.D. Green, D.E. Kirk, T.A. Hjalt, L. Sutherland, B.L. Thomas, M.L. Snead and B.A. Amendt. Univ. of Tulsa, Tulsa, OK, Univ. of Iowa, Iowa City, IA, Univ. of London, UK and Univ. of Southern California, Los Angeles, CA. 446 B156 Identification of differentially expressed genes in Tabbymutant mice using subtractive hybridization. R.T. Jaatinen and I. Thesleff. Univ. of Helsinki, Finland. 447 B157 Analysis of in vivo genetic ablation of the hippocampus, cingulate cortex and dentate gyrus in mice. O. Medina, H. Ma and M. Jamrich. Baylor Col. of Med., Houston, TX. 448 B158 The expression pattern of the cdo gene in the developing cerebral cortex. A. Okada and S. McConnell. Stanford Univ., Stanford, CA. 449 B159 The role of MEF2C in cardiac chamber specification. L.R. Jalbert, W. Bi, P. Cserjesi and J.J. Schwarz. Albany Med. Col., Albany, NY,, Univ. of Texas Med. Sch., Houston, TX. and Louisiana State Univ. Hlth. Sci. Ctr., New Orleans, LA. 450 B160 Developmental regulation of alternative splicing correlates with a switch from nuclear to cytoplasmic isoforms of the splicing activator, ETR-3. A.N. Ladd and T.A. Cooper. Baylor Col. of Med., Houston, TX. 451 B161 Pax3 hypaxial muscle expression is regulated by unique and separable enhancer elements. C.B. Brown and J.A. Epstein. Univ. of Pennsylvania, Philadelphia, PA. 452 B162 Conservation of adjacent Pax3 and Sox10 binding sites in mouse and human c-ret enhancer. D. Lang and J.A. Epstein. Univ. of Pennsylvania, Philadelphia, PA. 453 B163 Identifying regulatory regions conferring progenitor versus post-mitotic neuron expression of a retinal transcription factor. S. Rowan and C.L. Cepko. Harvard Med. Sch., Boston, MA. 454 B164 Mouse Six3 interacts with the Groucho-like Grg protein and functions as a transcriptional repressor. C.C. Zhu, O.V. Lagutin and G. Oliver. St. Jude Children's Res. Hosp., Memphis, TN. 455 B165 Quantification of right-handed b-DNA in hereditary cataracts.. C.E. Gagna, E. Lorig, J. Coutinho and W.C. Lambert. New York Inst. of Technol.-Life Sci., Old Westbury, NY and UMDNJ-Med. Sch., Newark, NJ. 456 B166 Characterization of the zebrafish ortholog of the human tumor suppressor FHIT. A.P. O'Connor, Y. Pekarsky, C. Croce, C. Brenner and S.A. Farber. Thomas Jefferson Univ., Philadelphia, PA. Patterning 457 B167 Possible involvement of light and auxin in plant-plant interaction. M. Fellner, A. Cocke, L. Horton, E.D. Ford, J.D. Cohen, and E. Van Volkenburgh. Univ. of Washington, Seattle, WA and Univ. of Minnesota, Saint Paul, MN. 458 B168 Evidence for independent systems for the communication of positional information in epithelial and interstitial cells in Hydra. S.L. Kauffman, S. Sherman and A. Grens. Indiana Univ., South Bend, IN. 459 B169 Regulation of cell fusion in C. elegans. S. Alper and C. Kenyon. Univ. of California, San Francisco, CA. 460 B170 p38 activity is required for embryonic skeletal patterning in the sea urchin. C.A. Bradham and D.R. McClay. Duke Univ., Durham, NC. 461 B171 T-box genes in the sea urchin, Lytechinus variegatus. J.M. Gross and D.R. McClay. Duke Univ., Durham, NC. 462 B172 Goosecoid and BMP2/4-Smad5 pathways have separable roles along the sea urchin embryo oral-aboral axis. L.M. Angerer, D.W. Oleksyn, A.M. Levine, X. Li, W.H. Klein and R.C. Angerer. Univ. of Rochester, Rochester, NY and Univ. of Texas MD Anderson Cancer Ctr., Houston, TX. 463 B173 Statistical features of expression of the segmentation genes in early Drosophila development at single-nucleus resolution. A.V. Spirov, D.M. Holloway, D. Kosman and J. Reinitz. Russian Acad. of Sci., St. Petersburg,, Russia, Univ. of British Columbia, Vancouver, Canada, Univ. of California, San Diego, CA and SUNY at Stony Brook, NY. 464 B174 Drosophila bunched maintains a cell fate boundary by regulating Notch signaling. L.A. Raftery and L.L. Dobens. Massachusetts Gen. Hosp., Harvard Med. Sch., Charlestown, MA. 465 * Ras1 is required cell autonomously in the Drosophila follicular epithelium for pipe repression and dorsal follicle cell migration. K.E. James and C.A. Berg. Univ. of Washington, Seattle, WA. * Poster moved to Poster Session I, B112 466 B176 Isolation of factors that directly interact with Sine oculis. K.L. Kenyon, C.R. Clouser and F. Pignoni. Harvard Med. Sch./MEEI, Boston, MA. 467 B177 The Drosophila Dx16 gene encodes a member of the Serine/Arginine rich family of splicing factors that affects pattern formation in imaginal discs. W. Xie, R. Battye and G.L. Boulianne. Hosp. for Sick Children, Toronto, Canada, Univ. of Toronto, Canada and Southeast Univ. Med. Sch., Nanjing, P.R. China. 468 B178 Generating and interpreting graded positional information in the Drosophila wing. G. Campbell. Univ. of Pittsburgh, Pittsburgh, PA. 469 B179 Short gastrulation interacts with integrins during wing vein development. H.M. Araujo, E.M. Negreiros and E. Bier. Fed. Univ.of Rio de Janeiro, Brazil and Univ. of California at San Diego, CA. 470 B180 EGF and TGF-β signaling collaborate in the patterning of the follicular epithelium during Drosophila oogenesis. F. Peri, A. Klaes and S. Roth. Univ. of Cologne, Koeln, Germany. 471 B181 Might sperm chromatin condensation patterns be determined kinetically, e.g. by reaction-diffusion?. L.G. Harrison, H.E. Kasinsky and M. Chiva. Univ. of British Columbia, Vancouver, Canada and Univ. of Barcelona, Spain. 472 B182 A mutagenesis screen to identify maternal factors required in early zebrafish development. D.S. Wagner, R. Dosch, K.A. Mintzer and M.C. Mullins. Univ. of Pennsylvania Med. Sch., Philadelphia, PA 473 B183 Phenotypic analysis of a mutation that disrupts segmental gene expression in zebrafish. K.K. Dill and S.L. Amacher. Univ. of California, Berkeley, CA. 474 B184 Cloning and charcterization of novel T-box genes in zebrafish. M. Nikaido and K. Araki. Natl. Res. Inst. of Aquaculture, Mie,, Japan. 475 B185 Mutations affecting neural crest development in the zebrafish. A. Barrallo Gimeno and E.W. Knapik. GSF Res. Ctr. for Envrn. and Health. Neuherberg. Germany. 476 B186 Bonnie and clyde functions in axial mesendoderm to regulate the Wnt inhibitor, dickkopf-1 in anterior patterning. L.A. Trinh and D.Y.R. Stainier. Univ. of California, San Francisco, San Francisco, CA 477 B187 Fgf8 and gFgf function to regulate the production of posterior mesoderm in zebrafish. B.W. Draper, D.W. Stock and C.B. Kimmel. Univ. of Oregon, Eugene, OR and Univ. of Colorado, Boulder, CO. 478 B188 The spatial and temporal role of lost-a-fin/activin receptor-like kinase 8 in vertebrate dorsoventral patterning. K.A. Mintzer and M.C. Mullins. Univ. of Pennsylvania Sch. of Med., Philadelphia, PA 479 B189 Pbx and Meis genes are essential for the specification of rhombomere identity in zebrafish. A.J. Waskiewicz, H.A. Rikhof, H. Popperl and C.B. Moens. Fred Hutchinson Cancer Res. Ctr., Seattle, WA and Deutsches Krebsforschungszentrum, Heidelberg, Germany. 480 B190 The role of placticity in boundary formation in the zebrafish hindbrain. J.E. Cooke and C.B. Moens. HHMI, Fred Hutchinson Cancer Res. Ctr., Seattle, WA. 481 B191 Withdrawn 482 B192 Spiel ohne grenzen / pou2 is required for early steps in the establishment of the zebrafish mid-/hindbrain boundary. H.-G. Belting, G. Hauptmann, D. Meyer, S. Abdelilah-Seyfried, A.J. Chitnis, C. Eschbach, C. Thisse, B. Thisse, I. Soll, K.B. Artinger and W. Driever. Univ. Freiburg, Germany, Univ. of California, San Francisco, CA, NIH/NICHD, Bethesda, MD, IGBMC, Illkirch, France and Harvard Med. Sch., Boston, MA. 483 B193 Characterization of caudal hindbrain defective, a novel gene which affects caudal hindbrain pattern in zebrafish. E.L. Wiellette and H.L. Sive. Whitehead Inst. for Biomed. Res., Cambridge, MA. 484 B194 Analysis of the role of dlx3 and dlx7 in zebrafish sensory placode development. K.S. Solomon and A. Fritz. Emory Univ., Atlanta, GA. 485 B195 The role of SHH in patterning the zebrafish pituitary gland. J.L. Sbrogna and R. Karlstrom. Univ. of Massachusetts, Amherst, MA,. 486 B196 The kruppel-like factor biklf mediates erythroid cell differentiation in zebrafish. A. Kawahara and I.B. Dawid. Natl. Inst. of Child Hlth. and Human Devel., Natl. Inst. of Hlth., Bethesda, MD. 487 B197 Large scale mutagenesis screen to define hemangioblast development in the zebrafish. B. Schmid, K.A. Dooley, A. Davidson, N. White, The Tubingen 2000 screen consortium and L.I. Zon. Children's Hosp., Howard Hughes Med. Inst., Boston, MA, Artemis Pharmaceuticals, Tubingen, Germany and Max-Planck Inst. for Entwicklungbiologie, Tubingen, Germany. 488 B198 The FGFR pathway is required for the trunk-inducing functions of Spemann's organizer. T.M. Smith and M.D. Sheets. Univ. of Wisconsin, Madison, WI. 489 B199 The competence to establish Spemann's organizer is actively restricted in space and time. V. Levy, K. Marom, S. Zins, N. Koutsia, R. Yelin and A. Fainsod. Hebrew Univ., Hadassah Med. Sch., Jerusalem, Israel. 490 B200 Dorsal inductive competence and the Wnt pathway. R.S. Darken, A.M. Zappia and P.A. Wilson. Cornell Univ. Med. Col., New York, NY. 491 B201 Regulation of BMP signaling by Chordin, Xolloid and Twisted gastrulation. M. Oelgeschlager, J. Larrain, N. Ketpura, B. Reversade and E.M. De Robertis. UCLA, Los Angeles, CA. 492 B202 Bicaudal-C is a localized maternal mRNA involved in endoderm development. O. Wessely, U. Tran, L. Zakin and E.M. De Robertis. HHMI/UCLA, Los Angeles, CA. 493 B203 Maternal Dapper is required for the specification of dorsal/anterior structures in vertebrate development. J.S. Waxman, J.D. Brown, J.B. Webster, B.N.R. Cheyette and R.T. Moon. Univ. of Washingtn, Seattle, WA and Univ. of Washington Sch. of Med., Seattle, WA. 494 B204 Syndecan 2 mediates early Xenopus left-right development as a functionally asymmetric coordinator. K. Kramer and H. Yost. Univ. of Utah, Salt Lake City, UT. 495 B205 The novel gene Ashwin functions in neural specification and axial patterning in Xenopus. S.S. Patil, T.B. Alexander, J.A. Uzman and A.K. Sater. Univ. of Houston, Houston, TX and Univ. of Houston-Downtown, Houston, TX. 496 B206 Pitx genes act as co-factors of otx2 in the specification of the cement gland. A. Schweickert, H. Steinbeisser and M. Blum. Forschungszentrum Karlsruhe, Karlsruhe and Max-Planck-Institut, Tübingen, Germany. 497 B207 Characterization of the Xenopus laevis Rx1A promoter in transgenic frogs. H.M. El-Hodiri, L. Zhang, H.F. Ma and M. Jamrich. Baylor Col. of Med., Houston, TX. 498 B208 Analysis of genes expressed during Xenopus laevis hind limb regeneration using subtractive hybridization. M. King, T. Nguyen, A. Mescher, M. Harty, C. Chalfant, P. Sankhavaram, D. Stocum, R. Smith and A. Neff. Terre Haute Ctr. for Med. Educ., Terre Haute, IN, Indiana Univ., Bloomington, IN, IUPUI, Indianapolis, IN and Lilly Res. Labs., Indianapolis, IN. 499 B209 cGMP enhances the Shh response in neural plate cells. C.P. Robertson, S.M. Gibbs and H. Roelink. Univ. of Washington, Seattle, WA. 500 B210 The zona limitans intrathalamica as a signaling center in forebrain development. M. Braun and H. Roelink. Univ. of Washington, Seattle, WA. 501 B211 In vivo electroporation of cDNA into heart tissue: cell fate control by Notch after linear heart tube stage in the chick. J.B. Rutenberg and M. Mercola. Harvard Med. Sch., Boston, MA. 502 B212 A role for carboxypeptidase Z in somite differentiation. C. Moeller, E.C. Swindell and G. Eichele. Max Planck Inst. for Exptl. Endocrinol., Hannover, Germany and Baylor Col. of Med., Houston, TX. 503 B213 FGF signaling regulates expression of Tbx2, Erm, Pea3 and Pax3 during chick craniofacial development. N. Firnberg and A. Neubuser. Inst. of Molec. Pathol., Vienna, Austria. 504 B214 Effect of the cleft primary palate mutation on chick craniofacial development. M.E. MacDonald and J.M. Richman. Univ. of British Columbia, Vancouver, Canada. 505 B215 Patterning of craniofacial skeleton by endogenous retinoids. J.N. Hui, V.M. Diewert and J.M. Richman. Univ. of British Columbia, Vancouver, Canada. 506 B216 Mechanism of epidermal growth factor action in avian skin development. R.P. Atit and L.A. Niswander. Sloan-Kettering Inst., New York, NY. 507 B217 BMP4 signaling in early mouse development. Q. Hu, N. Ueno and R.R. Behringer. Univ. of Texas, M.D. Anderson Cancer Ctr., Houston, TX. 508 B218 Overexpression of nodal in mouse embryonic stem cells results in upregulation of endoderm markers. K.C. Pfendler, C.S. Catuar, J.J. Meneses and R.A. Pedersen. Univ. of California, San Francisco, CA. 509 B219 Foxd3 in patterning the early mouse embryo. L.A. Hanna, D. Zhou, R. Foreman, M. Dottori, M. Goulding, D.S. Kessler and P.A. Labosky. Univ. of Pennsylvania, Philadelphia, PA and The Salk Inst., La Jolla, CA. 510 B220 The mouse organizer and its secreted factors Chordin and Noggin are unnecessary for anterior-posterior axis formation but are required for head development. J. Klingensmith, R. Stottmann, A. Nordgren and R. Anderson. Duke Univ. Med. Ctr., Durham, NC. 511 B221 Two separable elements regulate the expression of mouse Tbx6 in the primitive streak and presomitic mesoderm. E.E. McFadden and D.L. Chapman. Univ. of Pittsburgh, Pittsburgh, PA. 512 B222 Characterization of a novel mouse gene, cordon-bleu, expressed in embryonic axial and organizing structures. E.A. Carroll, S. Gasca and J. Klingensmith. Duke Univ. Med. Ctr., Durham, NC and Univ. of Freiburg, Freiburg, Germany. 513 B223 Shh is required for cardiac neural crest survival in the mouse. E.N. Meyers, I. Smoak, J. Morris, C. Tan, K. Yamamura and M. Sullivan. Duke Univ. Med. Ctr., Durham, N.C. and Kumamoto Univ. Sch. of Med., Kumamoto, Japan. 514 B224 Function of the Rx homeobox gene is essential for the formation of retinal progenitor cells in mice. L. Zhang, P.H. Mathers and M. Jamrich. Baylor Col. of Med., Houston, TX and West Virginia Univ. Sch. of Med., Morgantown, WV. 515 B225 Morphological characterization of lung and kidney development: reprogramming of ureter bud branching with lung mesenchyme towards early lung type branching morphogenesis. Y. Lin, S. Zhang, J. Tuukkanen, H. Peltoketo, T. Pihlajaniemi and S. Vainio. Univ. of Oulu, Finland and Collagen Res. Unit, Finland. 516 B226 Characterization of regulatory elements responsible for Hoxa5 regional expression. L. Jeannotte, J. Lapointe, S. Tabaries, T. Besch and C.K. Tuggle. Univ. Laval, Quebec, Canada and Iowa State Univ., Ames, IA. 517 B227 Footless, a new mutant with asymmetric limb malformations. S.M. Bell, C.M. Schreiner, K.P. Anderson and W.J. Scott. Children's Hosp. Med. Ctr., Cincinnati, OH. 518 B228 HoxD genes regulate muscle and tendon patterning in the limb. P.R. Ashby. Univ. of Dundee, Dundee, Scotland. 519 B229 Activation of FGFr3 regulates development of pillar cells in the mammalian cochlea. K. Mueller and M.W. Kelley. NIDCD/NIH, Rockville, MD. 520 B230 Inhibition of protein kinase C induces supernumerary inner hair cells in the developing mammalian cochlea. A. Dabdoub, M.J. Donohue and M.W. Kelley. Natl. Inst. on Deafness and other Communication Disorders/NIH, Rockville, MD. 521 B231 Msx and Dlx in feather development. I. Rouzankina, J. Zikherman and L.A. Niswander. Weill Grad. Sch. of Med. Sci. of Cornell Univ., New York, NY and Sloan-Kettering Inst., New York, NY. |
| 1:30-3pm | NIH
Workshop Zakir Bengali (NIH � Center for Scientific Review) The NIH Grants Process |
HUB Ballroom |
| 3:30-3:45pm | Break |
| 4-5:30pm | Workshops |
| 3. Developmental Biology and Disease Vectors | Kane 120 |
| Chair: | Laurence Zwiebel |
| 522 | 4:00 | Laurence
Zwiebel (Vanderbilt University) Molecular genetics of olfaction in the malaria vector mosquito Anopheles gambiae |
| 523 | 4:20 | Mohammed
Shahabuddin
(National
Institute of Allergy and Infectious Diseases, NIH) Drosophila as a model to study the biology of malaria transmission |
| 4:40 | Peter
Atkinson (UC Riverside) Gene transfer and expression in mosquitoes |
| 524 | 5:00 | Christopher
Bayne (Oregon State University) Aggression and defense in a trematode-mollusc parasitism |
| 5:20 | Discussion |
| 4. Left -Right Asymmetry | HUB Ballroom |
| Chair: | Christopher Wright |
| 4:00 | Christopher
Wright (Vanderbilt University Medical Center) Major issues in left-right axis determination |
| 525 | 4:20 |
Hiroshi
Hamada (Osaka University, Japan) Dissection of a genetic pathway generating left-right asymmetry in the mouse |
| 526 | 4:40 | Martina
Brueckner (Yale University) Mutation of the N-terminus of the left-right dynein (lrd) results in mice with non-random reversal of left-right asymmetry |
| 224 | 5:00 | Marnie
Halpern. (Carnegie Institution of Washington) Sequential regulation of left/right identity in the zebrafish diencephalon |
| 5:20 | Discussion |
| 5:30-7.00pm | Dinner | McMahon |
| 7-9 pm | Plenary
Session II Cell Fate Determination |
HUB Ballroom |
| Chair: | David Kimelman |
| 527 | 7:00 | David
Kimelman (University of Washington) Regulation of mesoderm induction and involution in zebrafish |
| 7:30 | Chris
Doe (University of Oregon) Cell polarity and asymmetric division of Drosophila neuroblasts |
|
| 528 | 8:00 |
Philip Benfey (New York University) Radial patterning in Arabidopsis: Signaling inside out |
| 529 | 8:30 | Hans
Bode (UC Irvine) Axial patterning in Hydra |
| 9-11pm | Poster Session II and Mixer | Upper Husky Den |
| Odd
number boards: Authors present at posters 1:30-3pm Even number boards: Authors present at posters 9-10:30pm |
| Saturday July 21st | ||
| 8am-5pm | Meeting Registration | Kane Lobby |
| 8-9am | Biotech/Imaging
Tutorials TBA |
| 9-11:15am | Plenary
Session III Color patterns |
HUB Ballroom |
| Chair: | Sean Carroll |
| 530 | 9:00 | Sean
Carroll (University Wisconsin-Madison)
The development and evolution of pigmentation patterns in Drosophila |
| 531 | 9:30 | Stephen
Johnson (Washington University) How the zebrafish gets its stripes |
| 532 | 10:00 | Greg
Barsh (Stanford University) Genetic and molecular basis of mammalian pigmentation patterns |
| 10:30 | Break | |
| 533 | 10:45 | Vivian
Irish (Yale University) Molecular mechanisms controlling floral pattern |
| 11:15am-12:15pm | E. G. Conklin Medal Lecture | HUB Ballroom |
| 11:15 | Sean
Carroll Introduction |
| 534 | 11:25 | Sir
John Gurdon (University of Cambridge, U.K.) From clones to morphogens: the determination of cell fate |
| 12:30-1:30pm | Lunch | McMahon |
| 1:30-5pm | Concurrent Symposia with 15 min coffee break around 3:15pm |
| 7. Programming and Reprogramming Differentiation | Kane 110 |
| Chair: | Austin Smith |
| 535 | 1:30 | Alejandro
Sanchez-Alvarado (Carnegie Institution of Washington) Maintenance and regeneration of form and function in the planarian Schmidtea mediterranea |
| 536 | 2:00 | Noel
Murcia (Case Western Reserve University) Polaris, the protein product of the Oak Ridge polycystic kidney disease gene is required for ventral node cell differentiation and node-to-notochord cell-fate transition |
| 537 | 2:15 | Austin
Smith (University of Edinburgh, Scotland) Self-renewal and differentiation of pluripotent embryonic stem cells |
| 538 | 2:45 | Brenda
Kahan (University of Wisconsin-Madison) Progenitors and differentiated progeny of pancreatic islet lineages derived by in vitro differentiation of embryonic stem (ES) cells |
| 539 | 3:00 | Heping
Liu (Baylor College of Medicine) The Mrx.1 gene is required for development of the early mouse embryo |
| 3:15 | Break | |
| 540 | 3:45 | Sean
J. Morrison (University of Michigan) Neural crest stem cells and peripheral nervous system development |
| 541 | 4:15 | Enrique
Amaya (University of Cambridge, U.K.) Xenopus Sprouty2 inhibits FGF mediated gastrulation movements but does not affect mesoderm induction and patterning |
| 542 | 4:30 | Peter
Mombaerts (Rockefeller University) Cloning mice by nuclear transfer |
| 8. Diversity of Form | Kane 120 |
| Chair: | Billie Swalla |
| 543 | 1:30 | Richard
Behringer (MD Anderson) Bat molecular embryology: Comparative studies of mammalian limb development |
| 544 | 2:00 | Scott
Gilbert (Swarthmore College) Development of the turtle shell: Osteogenesis of an evolutionary novel structure |
| 545 | 2:15 | Katie
Peichel (Stanford University) The genetic basis of morphological evolution in the threespine stickleback (Gasterosteus aculeatus) |
| 546 | 2:45 | Judith
Croxdale (University of Wisconsin-Madison) Trichome genes affect stomatal pattern |
| 547 | 3:00 | Patricia
Wittkopp (University of Wisconsin-Madison) The role of yellow in the evolution of pigmentation patterns in the genus Drosophila |
| 3:15 | Break | |
| 548 | 3:45 | Margaret
McFall-Ngai (University Hawaii-Manoa) The influences of bacteria on postembryonic animal development |
| 549 | 4:15 | Brad
Davidson (University of Washington) A developmental role for the immune system in Urochordate metamorphosis: molecular and morphological investigations of ascidian metamorphogenesis reveal elements of an innate immune response |
| 550 | 4:30 | Billie
Swalla (University of Washington) New perspectives of the origin of the Chordates |
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9. Developmental Biology and Medicine |
Kane 210 |
| Chair: | Leonard Zon |
| 551 | 1:30 | Marc
Tessier-Lavigne (UC San Francisco) The logic and mechanisms of axon guidance |
| 552 | 2:00 | Han
Wang (University of Oregon) Circadian expression of clock, bmal1 and per1 during zebrafish embryogenesis |
| 553 | 2:15 | Leonard
Zon (Children's Hospital, Boston) Screens in zebrafish for genes related to the cell cycle and cancer |
| 554 | 2:45 | Sally
Dunwoodie (Victor Chang Cardiac Research Institute) Delta3 mutational analysis in mouse defines the developmental origins of skeletal dysplasia in spondylocostal dysostosis |
| 555 | 3:00 | Beth
Roman (National Institute of Child Health and Human Development, NIH) The zebrafish mutant violet beauregarde exhibits abnormal cranial blood vessel development due toa lesion in alk1, the gene responsible for human hereditary hemorrhagic telangiectasia type II |
| 3:15 | Break | |
| George
Yancopoulos (Regeneron) Helping orphan receptors find their growth factors: Tales of neurons, muscle, cartilage, blood vessels and obesity |
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| 556 | 4:15 | Margaret
Baron (Mount Sinai School of Medicine) Activation of hematopoiesis and vasculogenesis by hedgehog signaling in the mouse embryo |
| 4:30 | 4:30
Eric Olson (UT Southwestern) Transcriptional control of cardiac form and function |
| 6pm- | Reception, Banquet and Awards Presentation | HUB Ballroom |
| Lifetime Achievement Award - Anne McLaren (University of Cambridge, U.K.) |
| Poster Competition Awards |
| Entertainment |
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Sunday July 22nd Departure |
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ACKNOWLEDGMENTS Grants Sponsors Exhibitors |
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SOCIETY FOR DEVELOPMENTAL BIOLOGY